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Authors = Maleeha Zahid

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3 pages, 165 KiB  
Case Report
COVID-19 Vaccine Failure in a Patient with Multiple Sclerosis on Ocrelizumab
by Sridhar Chilimuri, Nikhitha Mantri, Sudharsan Gongati, Maleeha Zahid and Haozhe Sun
Vaccines 2021, 9(3), 219; https://doi.org/10.3390/vaccines9030219 - 4 Mar 2021
Cited by 24 | Viewed by 5947
Abstract
Vaccines will play a key role in ending the COVID-19 pandemic. Vaccination against infections remains an important part of the management of patients with multiple sclerosis. However, there are limited data about the safety and efficacy of the currently available COVID-19 mRNA vaccines [...] Read more.
Vaccines will play a key role in ending the COVID-19 pandemic. Vaccination against infections remains an important part of the management of patients with multiple sclerosis. However, there are limited data about the safety and efficacy of the currently available COVID-19 mRNA vaccines in patients with multiple sclerosis receiving concurrent immunosuppressive therapies. Patients on B cell depleting therapy such as ocrelizumab have an attenuated vaccine response. We report the first case of COVID-19 vaccine failure in a patient with relapsing-remitting multiple sclerosis on B cell depleting therapy, ocrelizumab. We offer suggestions to improve vaccine efficacy in these patients. Full article
(This article belongs to the Section COVID-19 Vaccines and Vaccination)
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