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Authors = H. Kopelent-Frank

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6 pages, 1883 KiB  
Article
DENSITOMETRTSCHE UNTERSUCHUNGEN ZUR PHOTOSTABILITÄT VON MELOXICAM
by H. Bartsch, A. Eiper, B. Göls and H. Kopelent-Frank
Sci. Pharm. 2001, 69(4), 315-320; https://doi.org/10.3797/scipharm.aut-01-202 - 28 Dec 2001
Cited by 1 | Viewed by 1073
Abstract
Photodegradation of meloxicam is studied placing special emphasis on the investigation of the correlation between the sample concentration and the stability. For quantitation a HPTLC assay was developed. The stability indicating capability ofthe assay is proved using a sampie solution exposed to artificial [...] Read more.
Photodegradation of meloxicam is studied placing special emphasis on the investigation of the correlation between the sample concentration and the stability. For quantitation a HPTLC assay was developed. The stability indicating capability ofthe assay is proved using a sampie solution exposed to artificial irradiation from a xenon source, the peak of meloxicam was weil separated from all
degradation products. For quantitation external calibration is employed. Sample solutions of meloxicam of three different concentrations (2 mg ml-1; 250 μg ml-1 ; 40 μg ml-1) are subjected to simulated sunlight and tested for stability. Full article
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