Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Authors = Ensaf Y. Almomani

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
22 pages, 612 KiB  
Review
Intercalated Cells: More than pH Regulation
by Ensaf Y. Almomani, Sumanpreet Kaur, R. Todd Alexander and Emmanuelle Cordat
Diseases 2014, 2(2), 71-92; https://doi.org/10.3390/diseases2020071 - 8 Apr 2014
Cited by 3 | Viewed by 20274
Abstract
The renal collecting duct is the nephron segment where the final urine content of acid equivalents and inorganic ions are determined. The role of two different cell types present in this nephron segment has been determined many years ago: principal cells that express [...] Read more.
The renal collecting duct is the nephron segment where the final urine content of acid equivalents and inorganic ions are determined. The role of two different cell types present in this nephron segment has been determined many years ago: principal cells that express the epithelial sodium channel ENaC and aquaporin 2, regulate electrolyte reabsorption, while intercalated cells, which express acid-base transporters and vacuolar H+-ATPase, maintain an apropriate acid-base balance. Recent evidence challenges this historical view. Rather than having independent and non-overlapping functions, the two cell types in the collecting duct appear to functionally cooperate to regulate acid-base and volume homeostasis via complex paracrine and endocrine interplay. This review summarizes these recent findings. Full article
(This article belongs to the Special Issue Feature Papers)
Show Figures

Figure 1

Back to TopTop