Search Results (4)

The fast-moving world relies on intelligent connected networks to support the numerous applications of the expanded Internet-of-Things (IoT). The evolving communication requirements of this connected world require a new sixth generation (6G) radio to enable intelligent interaction with the massive number of connected objects. The energy management of billions of connected devices supporting massive Internet-of-Things (IoT) applications is the main challenge. These IoT devices and connected nodes are energy limited, and hence, energy-aware solutions are needed to enable seamless information flow between these communicating nodes. This paper presents an intelligent network solution for improved energy efficiency in a 6G-enabled expanded IoT network. A cell-free massive multiple input multiple output (mMIMO) technology is utilized for maximum energy efficiency with optimum network resource allocation. A practical power consumption model is proposed for the designed network topology which contains all the power components related to data transmission and circuit power. The proposed scheme aims to achieve maximum energy efficiency by the optimal allocation of pilot reuse factor and access point (AP) density for a given number of antennas at each AP and number of users. It is observed that the maximum energy efficiency of 5.2362 Mbit/Joule is achieved at the AP density of 29 and pilot reuse factor of 4 with PMMSE receive combining. In the end, the role of energy efficiency and area throughput tradeoff on the system performance is also evaluated, which suggests that both the energy efficiency and area throughput can be jointly increased until maximum energy efficiency is reached at a point. Full article

Electroporation is a next generation bioelectronics device. The emerging application of electroporation requires high voltage pulses having a pulse-width in the nanosecond range. The essential use of a capacitor results in an increase in the size of the electroporator circuit. This paper discusses the modification of a conventional Marx generator circuit to achieve the high voltage electroporation pulses with a minimal chip size of the circuit. The reduced capacitors are attributed to a reduction in the number of stages used to achieve the required voltage boost. The paper proposes the improved isolation between two capacitors with the usage of optocouplers. Parametric analysis is presented to define the tuneable range of the electroporator circuit. The output voltage of 49.4 V is achieved using the proposed 5-stage MOSFET circuit with an input voltage of 12 V. Full article

In the present study, perlite was thermally activated and then modified desirably to generate super acidity by loading different weight percentages of sulfated zirconia (SZ) via the two-step sol-gel method. As-prepared sulfated zirconia perlite (SZP) catalysts showed suitable catalytic potential in the vapor phase alkylation of o, m, and p-cresols with tert-butyl alcohol. The presence of crystalline phases in SZP catalysts was confirmed by XRD and FT-IR studies. TEM images revealed the nano size of the catalysts in the range of 9–25 nm. The presence of SZ on the surface of perlite was further confirmed by N₂ adsorption–desorption, SEM, SEM-EDX, TGA, and UV-Vis DRS techniques. The pyridine FT-IR results confirmed the existence of Brønsted, Lewis acidic sites and their combination as super acidic catalytic active centers on the surface of catalyst utilized in the vapor phase alkylation of o, m, and p-cresols with tert-butyl alcohol. The regeneration and reusability of the preferred catalyst until the 5th reaction cycle without any considerable loss in catalytic activity demonstrated the stability of the catalyst. Comparative studies show that SZP can be regenerated and is superior compared to other catalysts previously used for other alkylation reactions with the potential for use on a large scale. Full article

The directly compressible floating-bioadhesive tablets of tramadol were formulated using varying amounts Carbopol 971P (CP) and hydroxypropylmethyl cellulose (HPMC), along with other requisite excipients. In vitro drug release profile, floatational characteristics and ex vivo bioadhesive strength using texture analyzer were determined, and systematically optimized using a 3² central composite design (CCD). The studies indicated successful formulation of gastroretentive compressed matrices with excellent controlled release, mucoadhesion and hydrodynamic balance. Comparison of the dissolution profiles of the optimized formulation, with optimal composition of CP:HPMC :: 80.0:125.0, with that of the marketed controlled release formulation other indicated analogy of drug release performance with each other. Validation of optimization study using eight confirmatory experimental runs indicated very high degree of prognostic ability of CCD with mean ± SEM of −0.06% ± 0.37. Further, the study successfully unravels the effect of the polymers on the selected response variables. Full article