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10.21775/cimb.002.041
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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
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Review

Genetic Modification of Intestinal Lactobacilli and Bifidobacteria

by
Martin J. Kullen
and
Todd R. Klaenhammer
*
Department of Food Science, North Carolina State University, Raleigh, NC 27695-7624, USA
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2000, 2(2), 41-50; https://doi.org/10.21775/cimb.002.041
Submission received: 4 November 1999 / Revised: 4 February 2000 / Accepted: 11 March 2000 / Published: 1 April 2000
Versions Notes

Abstract

Lactobacilli and bifidobacteria are important members of the gastrointestinal microflora of man and animals. There is a substantial and growing body of evidence that these microbes provide benefits to the host in which they reside. Understanding the roles of these two groups of bacteria in the intestine continues to be a significant challenge. To this end, genetic characterisation and manipulation of intestinal lactobacilli and bifidobacteria is essential to define their contributions to the intestinal microflora, and to potentially exploit any beneficial or unique properties. This review will describe the tools and strategies currently available for the genetic manipulation of lactobacilli and bifidobacteria. Additionally, the ramifications and opportunities that may arise as a result of the genetic manipulation of probiotic lactobacilli and bifidobacteria will be addressed.

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MDPI and ACS Style

Kullen, M.J.; Klaenhammer, T.R. Genetic Modification of Intestinal Lactobacilli and Bifidobacteria. Curr. Issues Mol. Biol. 2000, 2, 41-50. https://doi.org/10.21775/cimb.002.041

AMA Style

Kullen MJ, Klaenhammer TR. Genetic Modification of Intestinal Lactobacilli and Bifidobacteria. Current Issues in Molecular Biology. 2000; 2(2):41-50. https://doi.org/10.21775/cimb.002.041

Chicago/Turabian Style

Kullen, Martin J., and Todd R. Klaenhammer. 2000. "Genetic Modification of Intestinal Lactobacilli and Bifidobacteria" Current Issues in Molecular Biology 2, no. 2: 41-50. https://doi.org/10.21775/cimb.002.041

APA Style

Kullen, M. J., & Klaenhammer, T. R. (2000). Genetic Modification of Intestinal Lactobacilli and Bifidobacteria. Current Issues in Molecular Biology, 2(2), 41-50. https://doi.org/10.21775/cimb.002.041

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