The “Drug Discovery, Development and Delivery” Section publishes original and innovative scientific papers, as well as comprehensive review papers. In this context, we are pleased to feature some recently published papers in Biomedicines (ISSN: 2227-9059) on drug discovery, drug design, basic and clinical pharmacology, formulation and delivery, and toxicology, which will provide valuable insights into this exciting field.

1. “Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy”
by Dongsik Park, Su Jin Lee and Jee-Woong Park
Biomedicines 2024, 12(1), 187; https://doi.org/10.3390/biomedicines12010187
Available online: https://www.mdpi.com/2227-9059/12/1/187

2. “The Use of Nigella sativa in Cardiometabolic Diseases”
by Giuseppe Derosa, Angela D’Angelo, Pamela Maffioli, Laura Cucinella and Rossella Elena Nappi
Biomedicines 2024, 12(2), 405; https://doi.org/10.3390/biomedicines12020405
Available online: https://www.mdpi.com/2227-9059/12/2/405

3. “Safety Profile of the Trastuzumab-Based ADCs: Analysis of Real-World Data Registered in EudraVigilance”
by Claudiu Morgovan, Carmen Maximiliana Dobrea, Anca Butuca, Anca Maria Arseniu, Adina Frum, Luca Liviu Rus, Adriana Aurelia Chis, Anca Maria Juncan, Felicia Gabriela Gligor, Cecilia Georgescu et al.
Biomedicines 2024, 12(5), 953; https://doi.org/10.3390/biomedicines12050953
Available online: https://www.mdpi.com/2227-9059/12/5/953

4. “Use of Oleuropein and Hydroxytyrosol for Cancer Prevention and Treatment: Considerations about How Bioavailability and Metabolism Impact Their Adoption in Clinical Routine”
by Francesco Gervasi and Fanny Pojero
Biomedicines 2024, 12(3), 502; https://doi.org/10.3390/biomedicines12030502
Available online: https://www.mdpi.com/2227-9059/12/3/502

5. “Vitamin D and Cardiovascular Diseases: From Physiology to Pathophysiology and Outcomes”
by Matteo Nardin, Monica Verdoia, Simone Nardin, Davide Cao, Mauro Chiarito, Elvin Kedhi, Gennaro Galasso, Gianluigi Condorelli and Giuseppe De Luca
Biomedicines 2024, 12(4), 768; https://doi.org/10.3390/biomedicines12040768
Available online: https://www.mdpi.com/2227-9059/12/4/768

6. “Recombinant Adeno-Associated Virus Vectors for Gene Therapy of the Central Nervous System: Delivery Routes and Clinical Aspects”
by Żaneta Słyk, Natalia Stachowiak and Maciej Małecki
Biomedicines 2024, 12(7), 1523; https://doi.org/10.3390/biomedicines12071523
Available online: https://www.mdpi.com/2227-9059/12/7/1523

7. “Repurposing of the Cardiovascular Drug Statin for the Treatment of Cancers: Efficacy of Statin–Dipyridamole Combination Treatment in Melanoma Cell Lines”
by Nanami Irie, Kana Mizoguchi, Tomoko Warita, Mirai Nakano, Kasuga Sasaki, Jiro Tashiro, Tomohiro Osaki, Takuro Ishikawa, Zoltán N. Oltvai and Katsuhiko Warita
Biomedicines 2024, 12(3), 698; https://doi.org/10.3390/biomedicines12030698
Available online: https://www.mdpi.com/2227-9059/12/3/698

8. “Role of Functionalized Peptides in Nanomedicine for Effective Cancer Therapy”
by Kibeom Kim and Myoung-Hwan Park
Biomedicines 2024, 12(1), 202; https://doi.org/10.3390/biomedicines12010202
Available online: https://www.mdpi.com/2227-9059/12/1/202

9. “Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications”
by Tingting He, Daria Giacomini, Alessandra Tolomelli, Monica Baiula and Luca Gentilucci
Biomedicines 2024, 12(2), 316; https://doi.org/10.3390/biomedicines12020316
Available online: https://www.mdpi.com/2227-9059/12/2/316

10. “Fluocinolone Acetonide Implant for Uveitis: Dissecting Responder and Non-Responder Outcomes at a Tertiary Center”
by Jasmin Abu Arif, Vitus André Knecht, Anne Rübsam, Vanessa Lussac, Zohreh Jami, Dominika Pohlmann, Bert Müller and Uwe Pleyer
Biomedicines 2024, 12(5), 1106; https://doi.org/10.3390/biomedicines12051106
Available online: https://www.mdpi.com/2227-9059/12/5/1106

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest to you:

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Biomedicines Editorial Office