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Romanian Journal of Preventive Medicine is published by MDPI from Volume 3 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Editura Universitară.
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Opinion

Vitamin K Prophylaxis for the Hemorrhagic Disease of the Newborns—A Short Narrative Review

by
Andreea Calomfirescu-Avramescu
and
Vlad Dima
Filantropia Clinical Hospital, Bucharest, Romania
Rom. J. Prev. Med. 2023, 2(1), 41-44; https://doi.org/10.3390/rjpm2010041
Published: 1 March 2023
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Abstract

Vitamin K deficiency bleeding (VKDB) affects 1 of 200 to 400 neonates who do not receive vitamin K prophylaxis. VKDB is classified by cause (idiopathic or secondary) and type (early, classic, late). The late type of VKDB is the least common and most severe with a mortality rate of 20%. AAP recommends that all neonates should receive a single dose of vitamin K1 soon after birth, which includes 0.5 to 1.0 mg of intramuscularly administered vitamin K1 or 1 to 2 mg of oral vitamin K1. Intramuscular administration is preferred and has more benefits than oral administration. The oral prophylaxis administration is controversial and in our Country is not available.
Keywords: vitamin K; bleeding prophylaxis; vitamin K deficiency; hemorrhagic disease of the newborn vitamin K; bleeding prophylaxis; vitamin K deficiency; hemorrhagic disease of the newborn

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MDPI and ACS Style

Calomfirescu-Avramescu, A.; Dima, V. Vitamin K Prophylaxis for the Hemorrhagic Disease of the Newborns—A Short Narrative Review. Rom. J. Prev. Med. 2023, 2, 41-44. https://doi.org/10.3390/rjpm2010041

AMA Style

Calomfirescu-Avramescu A, Dima V. Vitamin K Prophylaxis for the Hemorrhagic Disease of the Newborns—A Short Narrative Review. Romanian Journal of Preventive Medicine. 2023; 2(1):41-44. https://doi.org/10.3390/rjpm2010041

Chicago/Turabian Style

Calomfirescu-Avramescu, Andreea, and Vlad Dima. 2023. "Vitamin K Prophylaxis for the Hemorrhagic Disease of the Newborns—A Short Narrative Review" Romanian Journal of Preventive Medicine 2, no. 1: 41-44. https://doi.org/10.3390/rjpm2010041

APA Style

Calomfirescu-Avramescu, A., & Dima, V. (2023). Vitamin K Prophylaxis for the Hemorrhagic Disease of the Newborns—A Short Narrative Review. Romanian Journal of Preventive Medicine, 2(1), 41-44. https://doi.org/10.3390/rjpm2010041

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