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10.52010/ijom.1982.8.1.3
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International Journal of Orofacial Myology and Myofunctional Therapy is published by MDPI from Volume 51 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with the previous journal publisher.
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Case Report

A Pattern of Medication-Induced Persistent Bulbar and Cervical Dystonia

by
James F. Bosma
,
Virginia C. Geoffrey
,
Bradley T. Thatch
,
James M. Weiffenbach
,
James F. Kavanaugh
and
William Orr
Section on Oral and Pharyngeal Development, Clinical Investigations Branch, National Institute of Dental Research and Center for Research on Mothers and Children, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20205, USA
Int. J. Orofac. Myol. Myofunct. Ther. 1982, 8(1), 5-19; https://doi.org/10.52010/ijom.1982.8.1.3
Submission received: 1 March 1982 / Revised: 1 March 1982 / Accepted: 1 March 1982 / Published: 1 March 1982

Abstract

A longitudinal, analytical, and treatment oriented case study is presented describing the effects of a medication-induced impairment of neurological function. The subject is an elderly, Caucasian, female whose presenting symptoms included spasmodic eyelid movement; lack of muscle tone and control for specific muscles of the head and neck region; generalized hyperactivity; plus distortion of speech and deglutition. Clinical investigation determined that the subject’s timed release antihistamine medication was the primary etiological factor in the presenting symptoms. Discontinuation of the medication resulted in a decrease, but not complete remission, of the symptoms. Clinical evaluation of the residual speech impairment included intensive therapy which was only minimally successful in reducing propositional speech distortion. The patient's neuropathy was inferred to be suprabulbar in site as a result of the speech analysis which is described as a reliable diagnostic aid in evaluation of severity of this type of neurological pathology. During the eight years of observation of this subject, documentation of the impairment was made by means of various media. Some of the results of this documentation accompany the study.

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MDPI and ACS Style

Bosma, J.F.; Geoffrey, V.C.; Thatch, B.T.; Weiffenbach, J.M.; Kavanaugh, J.F.; Orr, W. A Pattern of Medication-Induced Persistent Bulbar and Cervical Dystonia. Int. J. Orofac. Myol. Myofunct. Ther. 1982, 8, 5-19. https://doi.org/10.52010/ijom.1982.8.1.3

AMA Style

Bosma JF, Geoffrey VC, Thatch BT, Weiffenbach JM, Kavanaugh JF, Orr W. A Pattern of Medication-Induced Persistent Bulbar and Cervical Dystonia. International Journal of Orofacial Myology and Myofunctional Therapy. 1982; 8(1):5-19. https://doi.org/10.52010/ijom.1982.8.1.3

Chicago/Turabian Style

Bosma, James F., Virginia C. Geoffrey, Bradley T. Thatch, James M. Weiffenbach, James F. Kavanaugh, and William Orr. 1982. "A Pattern of Medication-Induced Persistent Bulbar and Cervical Dystonia" International Journal of Orofacial Myology and Myofunctional Therapy 8, no. 1: 5-19. https://doi.org/10.52010/ijom.1982.8.1.3

APA Style

Bosma, J. F., Geoffrey, V. C., Thatch, B. T., Weiffenbach, J. M., Kavanaugh, J. F., & Orr, W. (1982). A Pattern of Medication-Induced Persistent Bulbar and Cervical Dystonia. International Journal of Orofacial Myology and Myofunctional Therapy, 8(1), 5-19. https://doi.org/10.52010/ijom.1982.8.1.3

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