CKD Patients’ Emotional Well-Being: An Examination of Their Psychological Stressors and Support Factors
Abstract
:1. Introduction
2. Methods
2.1. Participants and Procedures
2.2. Brief Symptom Inventory (BSI) [23]
2.3. COVID Impact Scale (CIS) [24]
2.4. The Physician–Patient Working Alliance Inventory (PPWAI) [20]
2.5. Social Support (MOS) [12]
2.6. Resilient Coping Measure (RCM) [27]
2.7. General Adherence Measure (GAM) [28]
2.8. Medical Patient Satisfaction Questionnaire (MPSQ) [20]
2.9. The World Health Organization Quality of Life-BREF (WHOQOL-BREF) [29]
3. Results
3.1. Hypothesis 1: Intercorrelations Among All Variables
3.2. Hypothesis 2: Regression Analyses Results
3.3. Hypothesis 3: Moderation Analyses Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Centers for Disease Control and Prevention (CDC). Chronic Kidney Disease Basics; Centers for Disease Control and Prevention: Atlanta, GA, USA, 19 August 2021. Available online: https://www.cdc.gov/kidney-disease/about/index.html (accessed on 30 June 2024).
- National Institute of Health. Kidney Disease Statistics for the United States; National Institute of Diabetes and Digestive and Kidney Diseases: Bethesda, MD, USA, 16 August 2023. Available online: https://www.niddk.nih.gov/health-information/health-statistics/kidney-disease#:~:text=Fast%20Facts%20on%20Kidney%20Disease,an%20estimated%2037%20million%20Americans.&text=For%20Americans%20with%20diabetes%20or,for%20CKD%20is%20even%20greater (accessed on 30 June 2024).
- American Kidney Fund (AKF). Chronic Kidney Disease (CKD) Symptoms, Treatment, Causes & Prevention; American Kidney Fund: Rockville, MD, USA, 2021; Available online: https://www.kidneyfund.org/kidney-disease/chronic-kidney-disease-ckd/ (accessed on 30 June 2024).
- United States Renal Data System (USRDS). USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States; USRDS: Minneapolis, MN, USA, 2020. Available online: https://pmc.ncbi.nlm.nih.gov/articles/PMC8148988/ (accessed on 30 June 2024).
- Williamson, E.J.; Walker, A.J.; Bhaskaran, K.; Bacon, S.; Bates, C.; Morton, C.E.; Curtis, H.J.; Mehrkar, A.; Evans, D.; Inglesby, P.; et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature 2020, 584, 430–436. [Google Scholar] [CrossRef] [PubMed]
- Bautovich, A.; Katz, I.; Smith, M.; Loo, C.K.; Harvey, S.B. Depression and chronic kidney disease: A review for clinicians. Aust. N. Z. J. Psychiatry 2014, 48, 530–541. [Google Scholar] [CrossRef] [PubMed]
- Grigoriou, S.S.; Karatzaferi, C.; Sakkas, G.K. Pharmacological and non-pharmacological treatment options for depression and depressive symptoms in hemodialysis patients. Health Psychol. Res. 2015, 13, 1–6. Available online: https://pmc.ncbi.nlm.nih.gov/articles/PMC4768541/ (accessed on 30 June 2024). [CrossRef]
- Chilcot, J.; Guirguis, A.; Friedli, K.; Almond, M.; Day, C.; Silva-Gane, M.; Davenport, A.; Fineberg, N.A.; Spencer, B.; Wellsted, D.; et al. Depression Symptoms in Haemodialysis Patients Predict All-Cause Mortality but Not Kidney Transplantation: A Cause-Specific Outcome Analysis. Ann. Behav. Med. 2018, 52, 1–8. [Google Scholar] [CrossRef]
- Walters, B.A.J.; Hays, R.D.; Spritzer, K.L.; Fridmanm, M.; Carter, W.B. Health-related quality of life, depressive symptoms, anemia, and malnutrition at hemodialysis initiation. Am. J. Kidney Dis. 2002, 40, 1185–1194. [Google Scholar] [CrossRef] [PubMed]
- Khalil, A.A.; Frazier, S.K.; Lennie, T.A.; Sawaya, B.P. Depressive symptoms and dietary adherence in patients with end-stage renal disease. J. Ren. Care 2011, 37, 30–39. [Google Scholar] [CrossRef]
- Head, K.J.; Forster, A.K.; Harsin, A.; Bartlett-Ellis, R.J. Identifying sources of patient dissatisfaction when seeking care for a chronic and complex disease. Patient Exp. J. 2023, 10, 94–102. [Google Scholar] [CrossRef]
- Sherbourne, C.D.; Stewart, A.L. The MOS social support survey. Soc. Sci. Med. 1991, 32, 705–714. [Google Scholar] [CrossRef]
- Kimmel, P.L.; Fwu, C.W.; Abbott, K.C.; Moxey-Mims, M.M.; Mendley, S.; Norton, J.M.; Eggers, P.W. Psychiatric Illness and Mortality in Hospitalized ESKD Dialysis Patients. Clin. J. Am. Soc. Nephrol. 2019, 14, 1363–1371. [Google Scholar] [CrossRef]
- Pompili, M.; Venturini, P.; Montebovi, F.; Forte, A.; Palermo, M.; Lamis, D.A.; Serafini, G.; Amore, M.; Girardi, P. Suicide risk in dialysis: Review of current literature. Int. J. Psychiatry Med. 2013, 46, 85–108. [Google Scholar] [CrossRef]
- Li, H.; Jiang, Y.; Lin, C.C. Factors associated with self-management by people undergoing hemodialysis: A descriptive study. Int. J. Nurs. Stud. 2014, 51, 208–216. [Google Scholar] [CrossRef]
- Hopwood, M.; Treloar, C. Resilient coping: Applying adaptive responses to prior adversity during treatment for Hepatitis C infection. J. Health Psychol. 2008, 13, 17–27. [Google Scholar] [CrossRef] [PubMed]
- Fung, S.F. Validity of the Brief Resilience Scale and Brief Resilient Coping Scale in a Chinese Sample. Int. J. Environ. Res. Public Health 2020, 17, 1265. [Google Scholar] [CrossRef] [PubMed]
- Oh, H.S.; Park, J.S.; Seo, W.S. Psychosocial influencers and mediators of treatment adherence in haemodialysis patients. J. Adv. Nurs. 2013, 69, 2041–2053. [Google Scholar] [CrossRef]
- Bordin, E.S. The generalizability of the psychoanalytic concept of the working, alliance. Psychother. Theory Res. Pract. 1979, 16, 252–260. [Google Scholar] [CrossRef]
- Fuertes, J.N.; Mislowack, A.; Bennett, J.; Paul, L.; Gilbert, T.C.; Fontan, G.; Boylan, L.S. The physician–patient working alliance. Patient Educ. Couns. 2007, 66, 29–36. [Google Scholar] [CrossRef] [PubMed]
- Fuertes, J.N.; Toporovsky, A.; Reyes, M.; Osborne, J.B. The physician-patient working alliance: Theory, research, and future possibilities. Patient Educ. Couns. 2017, 100, 610–615. [Google Scholar] [CrossRef]
- Cohen, J. A power primer. In Methodological Issues & Strategies in Clinical Research; Kazdin, A.E., Ed.; American Psychological Association: Washington, DC, USA, 2003; pp. 427–436. [Google Scholar]
- Derogatis, L.R. BSI Brief Symptom Inventory. In Administration, Scoring, and Procedures Manual, 4th ed.; National Computer Systems: Minneapolis, MN, USA, 1993. [Google Scholar]
- Fuertes, J.N.; Nandoo, L.; Moore, M.; Anand, P.; Kumar, S. Psychological Stress Among Rheumatology and Endocronology Patients. In Proceedings of the Annual Conference of the American Psychological Association, Washington, DC, USA, 3–5 August 2023. [Google Scholar]
- Horvath, A.O.; Greenberg, L.S. Development and validation of the Working Alliance Inventory. J. Couns. Psychol. 1989, 36, 223–233. [Google Scholar] [CrossRef]
- Reyes, M.; Fuertes, J.N.; Moore, M.T.; Punnakudiyil, G.J.; Calvo, L.; Rubinstein, S. Psychological and relational factors in ESRD hemodialysis treatment in an underserved community. Patient Educ. Couns. 2021, 104, 149–154. [Google Scholar] [CrossRef]
- Sinclair, V.G.; Wallston, K.A. The Development and Psychometric Evaluation of the Brief Resilient Coping Scale. Assessment 2004, 11, 94–101. [Google Scholar] [CrossRef]
- Hays, R.D. The Medical Outcomes Study (MOS) measures of patient adherence. J. Behav. Med. 1994, 17, 361–367. [Google Scholar]
- WHOQOL Group. World Health Organization Quality of Life Assessment (WHOQOL): Development and general psychometric properties. Soc. Sci. Med. 1998, 46, 1569–1585. [Google Scholar] [CrossRef] [PubMed]
- Preacher, K.J.; Hayes, A.F. Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav. Res. Methods 2008, 40, 879–891. [Google Scholar] [CrossRef] [PubMed]
- Bossola, M.; Stasio, E.; Antocicco, M.; Pepe, G.; Tazza, L.; Zuccalà, G.; Laudisio, A. functional impairment is associated with increased risk of mortality in patients on chronic hemodialysis. BMC Nephrol. 2016, 17, 72. [Google Scholar] [CrossRef]
- Kimmel, P.L.; Peterson, R.A. Depression in end-stage renal disease patients treated with hemodialysis: Tools, correlates, outcomes, and needs. Semin. Dial. 2005, 18, 91–97. [Google Scholar] [CrossRef]
- Lopes, A.A.; Lantz, B.; Morgenstern, H.; Wang, M.; Bieber, B.A.; Gillespie, B.W.; Li, Y.; Painter, P.; Jacobson, S.H.; Rayner, H.C. Associations of self-reported physical activity types and levels with quality of life, depression symptoms, and mortality in hemodialysis patients: The DOPPS. Clin. J. Am. Soc. Nephrol. 2014, 9, 1702–1712. [Google Scholar] [CrossRef]
Measure | N | Mean | S.D. | Alpha | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1.PPWA | 92 | 63.61 | 10.18 | 0.91 | ||||||||
2.BSI | 97 | 14.82 | 20.40 | 0.95 | −0.07 | |||||||
3.C19A | 101 | 34.36 | 9.51 | 0.91 | 0.15 | −0.11 | ||||||
4.QOL | 80 | 93.30 | 14.32 | 0.90 | 0.51 ** | −0.34 * | −0.09 | |||||
5.SOS | 103 | 66.96 | 24.00 | 0.95 | 0.21 | −0.22 | 0.07 | 0.39 ** | ||||
6.RES | 110 | 13.75 | 4.01 | 0.86 | 0.23 | −0.02 | −0.02 | 0.23 | 0.18 | |||
7.GAM | 94 | 18.94 | 4.73 | 0.75 | 0.42 ** | −0.22 | 0.14 | 0.36 ** | 0.12 | 0.35 ** | ||
8.PSQ | 110 | 21.40 | 4.08 | 0.95 | 0.55 ** | −0.21 | 0.24 * | 0.41 ** | 0.20 | 0.26 * | 0.49 ** |
Predictor | β | t | α | VIF |
---|---|---|---|---|
PPWA | 0.420 | 3.46 | 0.001 | 1.16 |
a. Dependent Variable: Adherence. Adj R2 0.217, p < 0.002. | ||||
PPWA | 0.515 | 5.34 | 0.001 | 1.08 |
BSI | −0.18 | −2.01 | 0.048 | 1.01 |
b. Dependent Variable: Satisfaction: Adherence. Adj R2 0.348, p < 0.001. | ||||
PPWA | 0.389 | 3.49 | 0.001 | 1.15 |
SOS | 0.280 | 2.49 | 0.016 | 1.18 |
BIS | −0.348 | −3.26 | 0.002 | 1.06 |
c. Dependent Variable: Quality of Life: Adherence. Adj R2 0.348, p < 0.001. |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Fuertes, J.N.; Friedman, O.B.; Moore, M.T.; Rubinstein, S. CKD Patients’ Emotional Well-Being: An Examination of Their Psychological Stressors and Support Factors. Kidney Dial. 2025, 5, 26. https://doi.org/10.3390/kidneydial5020026
Fuertes JN, Friedman OB, Moore MT, Rubinstein S. CKD Patients’ Emotional Well-Being: An Examination of Their Psychological Stressors and Support Factors. Kidney and Dialysis. 2025; 5(2):26. https://doi.org/10.3390/kidneydial5020026
Chicago/Turabian StyleFuertes, Jairo N., Olivia B. Friedman, Michael T. Moore, and Sofia Rubinstein. 2025. "CKD Patients’ Emotional Well-Being: An Examination of Their Psychological Stressors and Support Factors" Kidney and Dialysis 5, no. 2: 26. https://doi.org/10.3390/kidneydial5020026
APA StyleFuertes, J. N., Friedman, O. B., Moore, M. T., & Rubinstein, S. (2025). CKD Patients’ Emotional Well-Being: An Examination of Their Psychological Stressors and Support Factors. Kidney and Dialysis, 5(2), 26. https://doi.org/10.3390/kidneydial5020026