Chronic Antibody-Mediated Liver Rejection: More than Meets the Eye
Abstract
:1. Introduction
2. Case Report
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board
Informed Consent
Data Availability Statement
Conflicts of Interest
References
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HLA Typing of Patient | A*01:01 A*30:02 B*49:01 B*50:02 C*06:02 C*07:01 DRB1*07:01 DRB1*08:01 DQA*02:01 DQA1*04:02 DQB1*02:01 DQB1*04:02 |
HLA Typing of First Donor | A*30:02 A*26:01 B*18:01 B*38:01 C*05:01 C*12:03 DRB1*03:01 DRB1*14:01 DQB1*02:01 DQB1*05:03 (DQA1*01:01 DQA1*05:01) ∫ |
HLA Typing of Second Donor | A*02:01 A*30:01 B*08:01 B*51:01 C*07:01 C*02:02 C*07:01 DRB1*03:01 DQB1*02:01 (DQA1*05:01) ∫ |
Biochemical Parameters of Liver Function | Mean (Min–Max) |
---|---|
Aspartate transaminase (AST) | 146.9 U/L (76–261) |
Alanine transaminase (ALT) | 87.6 U/L (59–114) |
Bilirubin | 15.7 mg/dL (6.6–24.9) |
Alkaline phosphatase (ALP) | 259 U/L (138–352) |
Gamma-glutamyltransferase (GGT) | 62.1 (33–90) |
SFI Units | MFI Units | Donor Antigens | CDC XM | FC XM |
---|---|---|---|---|
>100.000 | 4 | Forbidden | Probably positive | Positive |
100.000–40.000 | 4.000–1.500 | Risk | Probably negative | Probably positive |
40.000–20.000 | 1.500–800 | Undetermined | Negative | Probably negative |
<20.000 | <800 | No Risk | Negative | Negative |
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Rita, C.G.; Iturrieta-Zuazo, I.; Ballester-González, R.; Alonso-Alarcón, N.; Moreno-Moreno, E.; Castañer-Alabau, J.L.; Nieto-Gañán, I. Chronic Antibody-Mediated Liver Rejection: More than Meets the Eye. Transplantology 2021, 2, 1-7. https://doi.org/10.3390/transplantology2010001
Rita CG, Iturrieta-Zuazo I, Ballester-González R, Alonso-Alarcón N, Moreno-Moreno E, Castañer-Alabau JL, Nieto-Gañán I. Chronic Antibody-Mediated Liver Rejection: More than Meets the Eye. Transplantology. 2021; 2(1):1-7. https://doi.org/10.3390/transplantology2010001
Chicago/Turabian StyleRita, Claudia Geraldine, Ignacio Iturrieta-Zuazo, Rubén Ballester-González, Nieves Alonso-Alarcón, Esther Moreno-Moreno, José Luis Castañer-Alabau, and Israel Nieto-Gañán. 2021. "Chronic Antibody-Mediated Liver Rejection: More than Meets the Eye" Transplantology 2, no. 1: 1-7. https://doi.org/10.3390/transplantology2010001