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Co-Management of Active Tuberculosis and Diabetes Mellitus Under Supervised DOTS Strategy—A Saudi Perspective

Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45220, USA
Primary Health Care, Directorate of Health, Jizan 82511, Saudi Arabia
Public Health, Directorate of Health, Jizan 82511, Saudi Arabia
Author to whom correspondence should be addressed.
Reports 2018, 1(3), 25;
Received: 5 November 2018 / Revised: 6 December 2018 / Accepted: 10 December 2018 / Published: 12 December 2018
PDF [200 KB, uploaded 12 December 2018]


Tuberculosis (TB) is a global public health concern, specifically in countries which have high prevalence of HIV/AIDS, malnutrition, unhygienic conditions, etc. Some evidence has been presented that diabetes mellitus (DM) is a risk factor for TB. On the other hand, among those who have DM, TB infection enhances glucose intolerance and worsens glycemic control. The combination of TB and DM, due to immuno-compromised status of DM, can delay the healing process of TB. The focus of this paper is the World Health Organization directly observed treatment, short course (DOTS) program implemented in Gazan province, Saudi Arabia, to treat TB. The data included some patients with both TB and DM. The data has been analyzed to assess how effective the DOTS program was in managing TB. It was found that DM was not a significant factor in the outcome of TB treatment. We used the same data and observed that the non-significance of DM is due to heterogeneity of patient population, Saudis and Non-Saudis. The prevalence of DM was very high among Saudis. This is understandable in view of different lifestyles. Non-Saudis are predominantly Yemenis. For Saudis, DM was indeed found to play a role in the treatment outcome of TB, after an application of a classification tree methodology on the data. This is the main focus of the paper. View Full-Text
Keywords: diabetes; tuberculosis; DOTS diabetes; tuberculosis; DOTS
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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MDPI and ACS Style

Ali, S.; Rao, M.; Sahly, A.A.; Alfageeh, A.; Bakari, A. Co-Management of Active Tuberculosis and Diabetes Mellitus Under Supervised DOTS Strategy—A Saudi Perspective. Reports 2018, 1, 25.

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