Microemulsions are thermodynamically stable and transparent systems composed of an aqueous phase, oil, a surfactant, and usually also contain a co-surfactant []. They have the capacity to incorporate large quantities of hydrophilic and lipophilic active principles, protecting them from degradative reactions and ensuring delivery of the cosmetic actives []. Due to these characteristics, microemulsions are adequate for the delivery of topical cosmetic actives. In order to create microemulsions with dermatocosmetic applications, grape seed oil was used as the oily phase, Tween 80 and plurol diisostearique CG as the surfactant blend, and ethanol as a co-surfactant for some of the samples. All components are safe for skin and are used as cosmetic ingredients. The obtained systems (Figure 1) were physically characterized based on electrical conductivity, dynamic light scattering, and rheometric measurements.

Figure 1.
Appearance of the W IV microemulsions.
Funding
This work was supported by a grant of the Romanian Ministry of Research and Innovation, CCCDI—UEFISCDI, project number PN-III-P1-1.2-PCCDI-2017-0428, contract 40PCCDI/2018, within PNCDI III and by Romanian Ministry of Research and Innovation—MCI through INCDCP ICECHIM Bucharest 2019–2022 Core Program PN. 19.23—Chem-Ergent, Project No. 19.23.02.03.
References
- Mehta, D.; Rathod, H.; Shah, D.; Shah, C. A Review on Microemulsion Based Gel: A Recent Approach for Topical Drug Delivery System. Res. J. Pharm. Technol. RJPT 2015, 8, 118–126. [Google Scholar] [CrossRef]
- Sandra, H.; Alexandra, G.; Reinhard, H.H.N. Microemulsions—Modern Colloidal Carrier for Dermal and Transdermal Drug Delivery. J. Pharm. Sci. 2008, 97, 603–631. [Google Scholar]
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).