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Proceedings 2017, 1(6), 665;

Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase

Laboratory of Pharmaceutical Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food Sciences and Institute of Biomedicine (IBUB), University of Barcelona (UB), Av. Joan XXIII 27-31, E-08028 Barcelona, Spain
Department of Nutrition, Food Science and Gastronomy, Faculty of Pharmacy and Food Sciences, and IBUB, University of Barcelona, Av. Prat de la Riba 171, E-08921 Santa Coloma de Gramenet, Spain
Laboratório de Planejamento e Desenvolvimento de Fármacos-LPDF, Instituto de Ciências Exatas e Naturais-ICEN, Universidade Federal do Pará—UFPA, Av. Augusto Correa, Nº 1-Bairro: Guamá, Cep: 66.075-900 Belém-Pará, Brazil
Research Institute Hospital 12 de Octubre, Avda. de Cordoba s/n, 28041 Madrid, Spain
Department of Biochemistry and Molecular Biology, Universidad Complutense de Madrid, Facultad de Veterinaria, Ciudad Universitaria, 28040-Madrid, Spain
Presented at the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain, 8 September 2017.
Author to whom correspondence should be addressed.
Published: 18 October 2017
(This article belongs to the Proceedings of the 1st Molecules Medicinal Chemistry Symposium)
PDF [154 KB, uploaded 18 October 2017]
Note: In lieu of an abstract, this is an excerpt from the first page.


There currently exists a dire need for safe and inexpensive new antimalarial drugs, which are effective against multiple life cycle stages of Plasmodium falciparum, and act through mechanisms that differ from those of the available drugs to prevent drug resistance. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Pont, C.; Alencar, N.; Sola, I.; Linares, M.; Palma, L.D.; Barbaraci, C.; Sampedro, C.; Juárez-Jiménez, J.; Abad, P.; Pérez-Benavente, S.; Lameira, J.; Bautista, J.M.; Luque, F.J.; Muñoz-Torrero, D. Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. Proceedings 2017, 1, 665.

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