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Communication

High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil

1
School of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil
2
School of Medicine, Post Graduate Program in Pathology, Federal University of Ceará, Fortaleza 60411-750, Brazil
3
Christus University Center, Fortaleza 60190-180, Brazil
4
Health Secretariat of Ceará State, Fortaleza 60060-440, Brazil
*
Author to whom correspondence should be addressed.
Academic Editor: John Frean
Trop. Med. Infect. Dis. 2021, 6(3), 129; https://doi.org/10.3390/tropicalmed6030129
Received: 15 June 2021 / Revised: 8 July 2021 / Accepted: 10 July 2021 / Published: 13 July 2021
(This article belongs to the Special Issue COVID-19: Current Challenges and Future Perspectives)
In Brazil, the SARS-CoV-2 vaccination program has so far prioritized people over 75 years of age. By the end of March 2021, in Ceará State, a total of 313,328 elderly people had received at least one dose of vaccine (45% Oxford-AstraZeneca/Fiocruz and 55% CoronaVac-Sinovac/Butantan), and 159,970 had received two doses (83% CoronaVac-Sinovac/Butantan and 17% Oxford-AstraZeneca/Fiocruz). After a single dose, there was already a significant reduction in COVID 19-related deaths (protection ratio: 19.31 (95% CI: 18.20–20.48), attributable protection ratio: 94.8%); higher protection ratios were observed after the application of two doses of the vaccine (132.67; 95% CI: 109.88–160.18), with an attributable protection ratio of 99.2%. SARS-CoV-2 vaccines are highly effective in reducing the number of COVID-19-related deaths in over 75-year-olds in Brazil, one of the hardest hit countries by the current pandemic. View Full-Text
Keywords: COVID-19; SARS-CoV-2; COVID-19 vaccines; mortality; epidemiology; public health COVID-19; SARS-CoV-2; COVID-19 vaccines; mortality; epidemiology; public health
MDPI and ACS Style

Alencar, C.H.; Cavalcanti, L.P.d.G.; Almeida, M.M.d.; Barbosa, P.P.L.; Cavalcante, K.K.d.S.; Melo, D.N.d.; de Brito Alves, B.C.F.; Heukelbach, J. High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil. Trop. Med. Infect. Dis. 2021, 6, 129. https://doi.org/10.3390/tropicalmed6030129

AMA Style

Alencar CH, Cavalcanti LPdG, Almeida MMd, Barbosa PPL, Cavalcante KKdS, Melo DNd, de Brito Alves BCF, Heukelbach J. High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil. Tropical Medicine and Infectious Disease. 2021; 6(3):129. https://doi.org/10.3390/tropicalmed6030129

Chicago/Turabian Style

Alencar, Carlos Henrique, Luciano Pamplona de Góes Cavalcanti, Magda Moura de Almeida, Patrícia Pereira Lima Barbosa, Kellyn Kessiene de Sousa Cavalcante, Déborah Nunes de Melo, Bruno Cavalcante Fales de Brito Alves, and Jorg Heukelbach. 2021. "High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil" Tropical Medicine and Infectious Disease 6, no. 3: 129. https://doi.org/10.3390/tropicalmed6030129

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