Preliminary Study of a Single Instillation of Low-Concentration High-Volume Silver Nitrate Solution for Chyluria: Is >10 mL Instillation an Absolute Contraindication in the Real World?
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients
2.2. Ethics
2.3. Treatment
2.4. Evaluation
3. Results
3.1. Characteristics of the Study Population
3.2. Efficacy
3.3. Complications
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Case | Sex | Age | Anesthesia | Side | Concentration (%) | Quantity (ml) |
---|---|---|---|---|---|---|
1-1 | Male | 79 | spinal | bilateral | 0.1 | 30, 30 |
1-2 | no anesthesia | bilateral | 0.2 | 25, 25 | ||
2 | Female | 66 | spinal | left | 0.5 | 15 |
3 | Male | 76 | spinal | left | 0.5 | 20 |
4-1 | Female | 72 | no anesthesia | left | 0.1 | 15 |
4-2 | no anesthesia | left | 0.5 | 25 | ||
5 | Male | 59 | general | right | 0.5 | 30 |
6 | M | 69 | spinal | left | 0.5 | 15 |
7 | F | 59 | no anesthesia | right | 0.25 | 15 |
8 | F | 66 | spinal | left | 0.5 | 15 |
9 | F | 85 | spinal | left | 0.5 | 30 |
Case | Therapeutic Effect | Complications | Hospital Stay (day) | Follow-up Periods (mos) | ||||
---|---|---|---|---|---|---|---|---|
Chyluria | Urine Protein | Serum TP (g/dL)/Alb (g/dL) | ||||||
Pre-Tx | Post-Tx | Pre-Tx | Post-Tx | |||||
1-1 | recurrence(5 days) | 3+ | ± | 4.8 /2.3 | 5.8 /2.8 | none | 14 | 165 |
1-2 | disappearance | ± | − | |||||
2 | disappearance | 3+ | − | 6.0 /3.7 | 6.6 /3.8 | none | 5 | 137 |
3 | disappearance | 4+ | − | 4.9 /3.1 | 6.8 /4.4 | fever (grade 1) nausea (grade 1) hypotension (grade 1) | 9 | 60 |
4-1 | recurrence(4 months) | 4+ | − | 5.4 /3.2 | 5.7 /3.4 | none | 3 | 87 |
4-2 | disappearance | 4+ | − | fever (grade 1) pain (grade 1) | 4 | |||
5 | disappearance | 1+ | − | − | − | none | 9 | 58 |
6 | disappearance | 1+ | − | − | − | pain (grade 2) | 10 | 55 |
7 | disappearance | 3+ | − | 6.4 /4.0 | 6.9 /4.1 | pain (grade 2) | 6 | 45 |
8 | disappearance | 3+ | − | 6.4 /3.9 | 6.7 /4.0 | none | 4 | 44 |
9 | disappearance | 3+ | − | 5.3 /3.2 | 6.0 /3.6 | none | 4 | 12 |
Authors (References) | No. Pts | Number of SNIs | Concentration (%) | Quantity (mL) | Severe Complications | Success Rate (%) |
---|---|---|---|---|---|---|
Goel et al. [2] | 44 | 9 | 1.0 | 6–10 | none | 75 |
Dhabalia et al. [3] | 59 | 3 or 9 | 1.0 | 5–7 | none | 95 |
Tan et al. [7] | 55 | 1–3 | 0.5 | 10 | unknown | 60 |
Sabnis et al. [8] | 62 | 4–12 | 1.0 | 10 | none | 66 |
Dalela et al. [25] | 54 | 1–4 | 1.0 | 5–10 | unknown | 54 |
Dalela et al. [19] | 47 | 3 or 9 | 1.0 | 8–10 | none | 68 |
Okamoto and Ohi [18] | 129 | 2–10 | 0.1–0.5 | 10 | unknown | 59 |
Authors (References) | Number of SNIs | Silver nitrate solution | Severe Complications | |
---|---|---|---|---|
Concentration (%) | Quantity (mL) | |||
Srivastava et al. [9] | 2 | 1 | unknown | arterial hemorrhage |
Su et al. [10] | 1 | 1 | 10 | acute necrotizing ureteritis |
Kulkarni et al. [11] | 1 | unknown | unknown | death (acute hepatic and renal failure) |
Dash et al. [20] | 1 | 3 | unknown | acute renal failure |
Mandhani et al. [21] | 1 | 3 | unknown | death (acute tubular necrosis) |
Abraham et al. [22] | 1 | 2 | 3 | acute renal failure |
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Mitsunari, K.; Imasato, Y.; Tsurusaki, T. Preliminary Study of a Single Instillation of Low-Concentration High-Volume Silver Nitrate Solution for Chyluria: Is >10 mL Instillation an Absolute Contraindication in the Real World? Trop. Med. Infect. Dis. 2019, 4, 128. https://doi.org/10.3390/tropicalmed4040128
Mitsunari K, Imasato Y, Tsurusaki T. Preliminary Study of a Single Instillation of Low-Concentration High-Volume Silver Nitrate Solution for Chyluria: Is >10 mL Instillation an Absolute Contraindication in the Real World? Tropical Medicine and Infectious Disease. 2019; 4(4):128. https://doi.org/10.3390/tropicalmed4040128
Chicago/Turabian StyleMitsunari, Kensuke, Yushi Imasato, and Toshifumi Tsurusaki. 2019. "Preliminary Study of a Single Instillation of Low-Concentration High-Volume Silver Nitrate Solution for Chyluria: Is >10 mL Instillation an Absolute Contraindication in the Real World?" Tropical Medicine and Infectious Disease 4, no. 4: 128. https://doi.org/10.3390/tropicalmed4040128
APA StyleMitsunari, K., Imasato, Y., & Tsurusaki, T. (2019). Preliminary Study of a Single Instillation of Low-Concentration High-Volume Silver Nitrate Solution for Chyluria: Is >10 mL Instillation an Absolute Contraindication in the Real World? Tropical Medicine and Infectious Disease, 4(4), 128. https://doi.org/10.3390/tropicalmed4040128