Next Article in Journal / Special Issue
Melioidosis in Bangladesh: A Clinical and Epidemiological Analysis of Culture-Confirmed Cases
Previous Article in Journal / Special Issue
Melioidosis in Thailand: Present and Future
Article Menu

Export Article

Open AccessReview
Trop. Med. Infect. Dis. 2018, 3(2), 39; https://doi.org/10.3390/tropicalmed3020039

Melioidosis in Vietnam: Recently Improved Recognition but still an Uncertain Disease Burden after Almost a Century of Reporting

1
Institute of Microbiology and Biotechnology, Vietnam National University, Hanoi 100000, Vietnam
2
Department of Academic Affairs, Phan Chau Trinh University, Quang Nam 560000, Vietnam
3
Department of Medical Microbiology, Hanoi Medical University, Hanoi 100000, Vietnam
4
National Hospital for Tropical Diseases, Hanoi 100000, Vietnam
5
Department of Infectious Diseases, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam
6
Department of Medical Microbiology, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam
7
Department of Infectious Diseases, University of Medicine and Pharmacy, Ho Chi Minh 700000, Vietnam
8
Hospital for Tropical Diseases, Ho Chi Minh 700000, Vietnam
9
Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, 8010 Graz, Austria
10
Department of Infectious Diseases, Bach Mai Hospital, Hanoi 100000, Vietnam
11
Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, 17475 Greifswald, Germany
*
Author to whom correspondence should be addressed.
Received: 12 March 2018 / Revised: 29 March 2018 / Accepted: 30 March 2018 / Published: 9 April 2018
(This article belongs to the Special Issue Global Burden and Challenges of Melioidosis)
Full-Text   |   PDF [2038 KB, uploaded 3 May 2018]   |  

Abstract

The first cases of human melioidosis were described in Vietnam in the 1920s, almost a century ago. It was in Vietnam in the thirties that the saprophytic nature of B. pseudomallei was first recognized. Although a significant number of French and U.S. soldiers acquired the disease during the Vietnam wars, indigenous cases in the Vietnamese population were only sporadically reported over many decades. After reunification in 1975, only two retrospective studies reported relatively small numbers of indigenous cases from single tertiary care hospitals located in the biggest cities in the South and the North, respectively. Studies from provincial hospitals throughout the country were missing until the Research Network on Melioidosis and Burkholderia pseudomallei (RENOMAB) project started in 2014. From then on seminars, workshops, and national scientific conferences on melioidosis have been conducted to raise awareness among physicians and clinical laboratory staff. This led to the recognition of a significant number of cases in at least 36 hospitals in 26 provinces and cities throughout Vietnam. Although a widespread distribution of melioidosis has now been documented, there are still challenges to understand the true epidemiology of the disease. Establishment of national guidelines for diagnosis, management, and reporting of the disease together with more investigations on animal melioidosis, genomic diversity of B. pseudomallei and its environmental distribution are required. View Full-Text
Keywords: melioidosis; Burkholderia pseudomallei; Vietnam; public awareness; animal; environment melioidosis; Burkholderia pseudomallei; Vietnam; public awareness; animal; environment
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Trinh, T.T.; Nguyen, L.D.N.; Nguyen, T.V.; Tran, C.X.; Le, A.V.; Nguyen, H.V.; Assig, K.; Lichtenegger, S.; Wagner, G.E.; Do, C.D.; Steinmetz, I. Melioidosis in Vietnam: Recently Improved Recognition but still an Uncertain Disease Burden after Almost a Century of Reporting. Trop. Med. Infect. Dis. 2018, 3, 39.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Trop. Med. Infect. Dis. EISSN 2414-6366 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top