Glucose Serum Concentrations and Cardiovascular Disease in Patients on the End Stage of Renal Disease without Diabetes Mellitus
Abstract
:1. Introduction
2. Material and Methods
2.1. Subjects
2.2. Blood Collection
2.3. Laboratory Measurements
2.4. Hemodynamic Measurements
3. Approval and Consent
4. Data Analysis
5. Results
Characteristic | Patients with Glucose Serum Concentrations Less than 114.5 mg/dL (n = 58, Mean ± SD or Mean Rank) | Patients with Glucose Serum Concentrations More than 114.5 mg/dL (n = 18, Mean ± SD or Mean Rank) |
---|---|---|
Age (years) | 60.8 ± 14.5 | 67.6 ± 15.5 |
Dialysis duration (years) | 37.8 | 36.4 |
BMI (Kg/m2) | 24.2 ± 2.9 | 25.3 ± 3.1 |
Urine ( mL/day ) | 226.2 ± 150.6 | 166.6 ± 115.4 |
KTVurea | 38.22 | 34.88 |
nPCR (g/Kg/day) | 2.3 ± 0.4 | 2.5 ± 0.6 |
Glucose (mg/dL) | 85.5 ± 13.7 | 132.7 ± 26.2 * |
SBP (mmHg) | 130.0 ± 20.7 | 138.3 ± 19.7 |
DBP (mmHg) | 80.8 ± 10.2 | 84.3 ± 7.7 |
MBP (mmHg) | 97.2 ± 12.9 | 102.3 ± 11.3 |
c-fPWV(m/s) | 11.1 ± 1.8 | 12.08 ± 1.7 |
Augmentation index (AIx) | 24.1 ± 2.3 | 24.4 ± 1.7 |
Pulse Pressure (PP, mmHg) | 55.4 ± 17.7 | 66.7 ± 20.8 * |
ABPI | 1.12 ± 0.4 | 1.12 ± 0.5 |
Hemoglobulin | 11.8 ± 1.3 | 12.01 ± 1.3 |
Monocytes (K/μL) | 0.49 ± 0.2 | 0.50 ± 0.2 |
insulin (μU/mL) | 32.7 | 54.7 * |
ΗΟΜΑ-ΙR (mmol/L) | 31.4 | 59.4 * |
hsCRP (mg/L) | 7.3 ± 6.03 | 10.6 ± 4.6 * |
beta2-microglobulin (mg/L) | 34.1 | 49.5 * |
i-PTH (pg/mL) | 38.2 | 34.6 |
Albumin (gr/dL) | 37.9 | 36.09 |
LDL/HDL | 2.3 ± 0.9 | 2.2 ± 0.7 |
ox-LDL (ng/mL) | 35.2 | 45.8 |
Correlations
Factors | B | S.E. | Sig. | Exp (B) |
---|---|---|---|---|
Glucose | −0.001 | 0.013 | 0.937 | 0.999 |
age | 0.064 | 0.03 | 0.042 | 1.066 |
hypertension | 1.042 | 0.75 | 0.169 | 2.836 |
BMI | −0.263 | 0.13 | 0.044 | 0.769 |
LDL/HDL | −1.288 | 0.55 | 0.020 | 0.276 |
Hb | 0.605 | 0.32 | 0.060 | 1.832 |
hsCRP | 0.092 | 0.06 | 0.164 | 1.097 |
oxLDL | 0.011 | 0.005 | 0.025 | 1.011 |
i-PTH | 0.004 | 0.002 | 0.025 | 1.004 |
Kt/Vurea | −5.816 | 2.9 | 0.044 | 0.003 |
Family history | 0.099 | 0.824 | 0.905 | 1.104 |
6. Discussion
7. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Raikou, V.D.; Kyriaki, D. Glucose Serum Concentrations and Cardiovascular Disease in Patients on the End Stage of Renal Disease without Diabetes Mellitus. J. Cardiovasc. Dev. Dis. 2015, 2, 66-75. https://doi.org/10.3390/jcdd2020066
Raikou VD, Kyriaki D. Glucose Serum Concentrations and Cardiovascular Disease in Patients on the End Stage of Renal Disease without Diabetes Mellitus. Journal of Cardiovascular Development and Disease. 2015; 2(2):66-75. https://doi.org/10.3390/jcdd2020066
Chicago/Turabian StyleRaikou, Vaia D., and Despina Kyriaki. 2015. "Glucose Serum Concentrations and Cardiovascular Disease in Patients on the End Stage of Renal Disease without Diabetes Mellitus" Journal of Cardiovascular Development and Disease 2, no. 2: 66-75. https://doi.org/10.3390/jcdd2020066