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Bioengineering 2017, 4(2), 55;

Recent Advances and Challenges towards Sustainable Polyhydroxyalkanoate (PHA) Production

UCIBIO-REQUIMTE, Department of Chemistry, Faculdade de Ciências e Tecnologia/Universidade Nova de Lisboa, 2829-516 Caparica, Portugal
Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK
Faculty of Engineering and the Environment, University of Southampton, Highfield, Southampton SO17 1BJ, UK
European Bioenergy Research Institute (EBRI), Aston University, Aston Triangle, Birmingham B4 7ET, UK
Department of Chemical and Biochemical Engineering, Center for Bioprocess Engineering, Søltofts Plads, Technical University of Denmark, Building 229, 2800 Kgs. Lyngby, Denmark
Author to whom correspondence should be addressed.
Academic Editor: Martin Koller
Received: 30 April 2017 / Revised: 29 May 2017 / Accepted: 9 June 2017 / Published: 11 June 2017
(This article belongs to the Special Issue Advances in Polyhydroxyalkanoate (PHA) Production)
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Sustainable biofuels, biomaterials, and fine chemicals production is a critical matter that research teams around the globe are focusing on nowadays. Polyhydroxyalkanoates represent one of the biomaterials of the future due to their physicochemical properties, biodegradability, and biocompatibility. Designing efficient and economic bioprocesses, combined with the respective social and environmental benefits, has brought together scientists from different backgrounds highlighting the multidisciplinary character of such a venture. In the current review, challenges and opportunities regarding polyhydroxyalkanoate production are presented and discussed, covering key steps of their overall production process by applying pure and mixed culture biotechnology, from raw bioprocess development to downstream processing. View Full-Text
Keywords: polyhydroxyalkanoates; biopolymers; renewable feedstock; mixed microbial consortia; enrichment strategy; pure cultures; synthetic biology; downstream processing polyhydroxyalkanoates; biopolymers; renewable feedstock; mixed microbial consortia; enrichment strategy; pure cultures; synthetic biology; downstream processing

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Kourmentza, C.; Plácido, J.; Venetsaneas, N.; Burniol-Figols, A.; Varrone, C.; Gavala, H.N.; Reis, M.A.M. Recent Advances and Challenges towards Sustainable Polyhydroxyalkanoate (PHA) Production. Bioengineering 2017, 4, 55.

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