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Biomedicines 2017, 5(1), 4;

The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering

Department of Urology, Davis School of Medicine, University of California, Sacramento, CA 95817, USA
Stem Cell Program, Institute for Regenerative Cures, University of California, Davis Medical Center, Sacramento, CA 95817, USA
Author to whom correspondence should be addressed.
Academic Editors: David T. Harris and Wenbin Deng
Received: 31 October 2016 / Revised: 23 December 2016 / Accepted: 26 December 2016 / Published: 6 January 2017
Full-Text   |   PDF [372 KB, uploaded 6 January 2017]   |  


Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder stones, and other long-term sequelae, raising the need for a source of safe and reliable bladder tissue. Advancements in stem cell biology have catapulted stem cells to the center of many current tissue regeneration and bioengineering strategies. This review presents the recent advancements in the use of stem cells in bladder tissue bioengineering. View Full-Text
Keywords: urothelium; tissue engineering; bladder; stem cells urothelium; tissue engineering; bladder; stem cells

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Chan, Y.Y.; Sandlin, S.K.; Kurzrock, E.A.; Osborn, S.L. The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering. Biomedicines 2017, 5, 4.

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