Sex Steroid Receptors in Polycystic Ovary Syndrome and Endometriosis: Insights from Laboratory Studies to Clinical Trials
Abstract
1. Introduction
2. Characteristics of Sex Steroid Receptors
2.1. Structure
2.2. Distribution
2.3. Physiological Functions
2.3.1. Oestrogen Receptors
2.3.2. Progesterone Receptors
2.3.3. Androgen Receptor
3. Sex Steroid Receptors in PCOS and Endometriosis
3.1. Abnormal Folliculogenesis in PCOS
3.2. Metabolic Disorders in PCOS
3.3. Endometriosis
4. Potential Therapeutic Routes
4.1. Receptor Agonist
4.2. Receptor Antagonist
5. Limitations
6. Recommendations
7. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Abdul Hamid, F.; Abu, M.A.; Abdul Karim, A.K.; Ahmad, M.F.; Abd. Aziz, N.H.; Mohd Kamal, D.A.; Mokhtar, M.H. Sex Steroid Receptors in Polycystic Ovary Syndrome and Endometriosis: Insights from Laboratory Studies to Clinical Trials. Biomedicines 2022, 10, 1705. https://doi.org/10.3390/biomedicines10071705
Abdul Hamid F, Abu MA, Abdul Karim AK, Ahmad MF, Abd. Aziz NH, Mohd Kamal DA, Mokhtar MH. Sex Steroid Receptors in Polycystic Ovary Syndrome and Endometriosis: Insights from Laboratory Studies to Clinical Trials. Biomedicines. 2022; 10(7):1705. https://doi.org/10.3390/biomedicines10071705
Chicago/Turabian StyleAbdul Hamid, Fazilah, Muhammad Azrai Abu, Abdul Kadir Abdul Karim, Mohd Faizal Ahmad, Nor Haslinda Abd. Aziz, Datu Agasi Mohd Kamal, and Mohd Helmy Mokhtar. 2022. "Sex Steroid Receptors in Polycystic Ovary Syndrome and Endometriosis: Insights from Laboratory Studies to Clinical Trials" Biomedicines 10, no. 7: 1705. https://doi.org/10.3390/biomedicines10071705
APA StyleAbdul Hamid, F., Abu, M. A., Abdul Karim, A. K., Ahmad, M. F., Abd. Aziz, N. H., Mohd Kamal, D. A., & Mokhtar, M. H. (2022). Sex Steroid Receptors in Polycystic Ovary Syndrome and Endometriosis: Insights from Laboratory Studies to Clinical Trials. Biomedicines, 10(7), 1705. https://doi.org/10.3390/biomedicines10071705