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Skin Protective Nutraceuticals: The Current Evidence in Brief

Obstetrics and Gynecology Locum Tenens, Salinas, CA 93902, USA
Healthcare 2018, 6(2), 40;
Received: 17 March 2018 / Revised: 16 April 2018 / Accepted: 1 May 2018 / Published: 4 May 2018
PDF [390 KB, uploaded 19 May 2018]


Nutraceuticals are important for healthy skin maintenance. Probiotics, phenolics, and vitamins are just a few of the nutraceuticals meant to potentially prevent and assist medical management of dermatologic conditions. Among these, probiotics, vitamin E, and green tea catechins may offer the broadest array of skin protective mechanisms with probiotics having the greatest clinical range. Probiotics’ amelioration of atopic dermatitis and opportunistic infections of skin burns has been targeted in recent research efforts. This includes the improvement of Scoring Atopic Dermatitis index scores, p = 0.02, with intact Lactobacillus rhamnosus Goldin and Gorbach (LGG) in comparison to heat inactivated LGG or placebo. Lactobacillus reuteri used prior to or concurrently with Staphylococcus aureus infection can increase epidermal keratinocyte survival, p < 0.01. Phenolics may not have been extensively studied for atopic dermatitis or skin burns. However, phenolics do have a role in photoprotection. The phenolic rutin increases ultraviolet B radiation filter reactive oxygen species scavenging at 75%, p < 0.002, and peak wavelength absorption, p < 0.001. While oral and topical probiotics have untapped potential for atopic dermatitis amelioration and skin infection prevention, phenolics will be increasingly used for photoprotection. With optimized bioavailability, dosage, and formulation, nutraceuticals will become crucial for healthy skin maintenance. View Full-Text
Keywords: atopic dermatitis; green tea; human skin; keratinocyte; moisturizer; nutraceuticals; photoprotection; polyphenols; probiotics; vitamin E atopic dermatitis; green tea; human skin; keratinocyte; moisturizer; nutraceuticals; photoprotection; polyphenols; probiotics; vitamin E
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Nwanodi, O. Skin Protective Nutraceuticals: The Current Evidence in Brief. Healthcare 2018, 6, 40.

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