Abstract
Background: Heat stress in agricultural work is a significant health risk, especially due to dehydration as a result of exposure to heat, physical exertion, and inadequate hydration practices. This problem becomes even more critical when working outdoors, where extreme conditions can intensify the effects. Objective: The main objective of the present study was to determine the existing interventions to prevent or mitigate dehydration among agricultural workers exposed to heat stress during their workday outdoors, in both real and simulated contexts. Methods: A systematic review was performed in accordance to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The search strategy combined MeSH terms and an open search in six scientific databases. Relevant studies were selected and data from the interventions were extracted, following the guidelines from the Joanna Briggs Institute (JBI) for systematic reviews. The studies were assessed with the Mixed Methods Appraisal Tool (MMAT) and the GRADE assessment framework. Results: Nine studies were included, which focused on interventions such as education programs, cooling devices, and hydration strategies. The results showed that adequate access to water, rest in the shade, the use of cooling bandanas, and hydration backpacks, were effective in reducing dehydration and heat stress among agricultural workers exposed to high temperatures. Conclusions: An integrated approach combining education, hydration, and workplace improvements is essential to prevent dehydration and heat stress among agricultural workers. While body cooling is promising, further research and investments in infrastructure are needed to ensure access to safe drinking water, shaded rest areas, cooling technologies, educational initiatives, and health monitoring systems.
1. Introduction
The concept of occupational heat stress usually refers to local workplace heat stress associated with environmental factors [1]. The most vulnerable population groups include workers who work outdoors in subtropical or tropical countries, low- or medium-income individuals, and employees in the production sector, such as agriculture, construction, and manufacturing [2]. Agricultural workers exposed to extreme heat face a heightened risk of heat stress, particularly due to prolonged exposure to temperatures often exceeding 30 °C (86 °F), limited mechanization, and, in some cases, the absence of occupational safety programs [2]. The environmental conditions of heat stress during the workday can lead to diverse health problems in agricultural workers, among which we find dehydration and renal failure, among other conditions. These health conditions have been documented in studies conducted across multiple continents [3,4,5,6,7,8], indicating that this is a global issue. Some contributing factors commonly identified include repeated volume depletion due to heat exposure and physical exertion, as well as inadequate hydration practices among agricultural workers [9]. These conditions can lead to kidney damage as a result of recurrent dehydration, reduced renal blood flow, increased tubular reabsorption demands, and elevated uric acid levels [10]. Therefore, thorough research is required to accurately assess the physiological impacts of these factors [11].
Exposure to extreme heat, a high physical workload, and inadequate hydration are key occupational risk factors contributing to dehydration among agricultural workers, alongside cultural or social aspects [12]. Addressing this issue requires not only the consideration of physical risks, but also psychological, social, and well-being dimensions [13]. Despite its relevance, dehydration remains underdocumented in the agricultural sector [8], even as studies highlight both sustained heat exposure and inconsistent regulatory compliance as aggravating factors [14]. In response, effective prevention and treatment strategies for heat-related dehydration must be context-specific and multidisciplinary [3,13]. OSHA emphasizes three core components in heat stress prevention: water access, rest breaks, and shaded areas [15], with water as the primary hydration fluid due to its fundamental role in physiological balance and disease prevention [16].
Scientific evidence shows that agricultural workers exposed to high temperatures during the workday are at considerable risk of dehydration, a risk that is often underestimated. This underscores the importance of implementing multidisciplinary prevention and treatment strategies tailored to environmental, occupational, and health-related factors. To date, no prior literature review has specifically focused on interventions targeting dehydration or heat stress among agricultural workers during their workday. In addition, it must be underlined that the incidence of heat stress will become an increasingly recurring event due to climate change and global warming, which underscores the importance of strengthening the protection of agricultural workers, in particular temporary migrant workers, an especially vulnerable group within the sector [8]. Addressing heat-related risks is essential for meeting some of the Sustainable Development Goals, such as SDG 3 (Good Health and Well-being) and SDG 8 (Decent Work and Economic Growth), and for ensuring the sustainability of the agricultural sector and the resilience of communities [2]. For this, the main objective of the present study was to determine the existing interventions to prevent or mitigate dehydration in agricultural workers exposed to heat stress during their workday outdoors, in both real and simulated contexts.
2. Materials and Methods
A systematic review of the literature was performed. Although reviews can address diverse objectives, most are oriented towards assessing an intervention or a treatment [2]; thus, experimental quantitative or quasi-experimental studies were selected. The process described in the Preferred Reporting Items for Systematic reviews and Meta-Analyses literature search extension (PRISMA) [17] was followed (Supplementary Material S1). The protocol was registered at Prospero with code CRD42024613308.
For the development of the study, the eight phases described by Aromataris et al., 2024 [18] were followed: (1) Determining the review question, (2) defining the inclusion and exclusion criteria, (3) finding studies through a search, (4) study selection for their inclusion, (5) evaluation of the study quality, (6) data extraction, (7) analysis and synthesis of the pertinent studies, and (8) presentation and interpretation of the results, potentially including a process for establishing the certainty of the set of evidence (through systems such as the Grading of Recommendations, Assessment, Development and Evaluations—GRADE). In particular, phase 8 is specifically developed in the results section.
2.1. PHASE 1: Determining the Review Question
A question was formulated based on the PICO (Population, Intervention, Comparison, Outcomes) method “What dehydration prevention and management measures have been applied to agricultural workers exposed to extreme heat conditions?”, and the FINER [19,20] (Feasible, Interesting, Novel, Ethical and Relevant) criteria (Supplementary Material S2).
2.2. PHASE 2: Definition of the Inclusion and Exclusion Criteria
The inclusion criteria were: (1) Quantitative studies, both experimental and quasi-experimental (pre and post, post-intervention) and mixed (with a quantitative phase), that describe an intervention; (2) Adult participants in an agricultural work situation, exposed to high temperature conditions outdoors or in an simulated environment; and (3) Articles published until November, 2024, without any limits placed on the start date. The exclusion criteria were: (1) Non-primary studies, literature reviews, editorials, or experts opinions; (2) Studies with animals or plants; (3) Studies that do not specifically address dehydration; (4) Studies in which the workday takes place indoors (farms, factories, etc.); (5) Articles that were not in English, Spanish, French, or Italian, and (6) Interventions based on pharmacological treatments.
2.3. PHASE 3: Finding Studies Through a Search
To find the studies, the Medical Subject Headings (MeSH) such as dehydration, water–electrolyte balance, agricultural workers’ diseases, hot temperature, and climate change were detailed, as well as open terms such as intervention, fluid intake, outdoor worker, and heat wave, among others.
Then, a search strategy was articulated into two elements: (1) databases, and (2) creation of search formulas. The databases used were: PubMed, Cinahl, Cuiden, US Department of Agriculture, National Agricultural Library, Scopus, WOS, Dialnet, Recercat, Recolecta, TDX, Dart Europe, and Open Access Theses and Dissertations, and the search formulas can be found in Supplementary Material S3. This strategy was led by an expert documentarian, a member of the research team (C.Ca).
2.4. PHASE 4: Study Selection for Their Inclusion
The articles obtained in the different databases were exported to Rayyan, through the WEB application. This platform accelerates the selection process and is highly usable [21]. A two-stage process was followed: (1) Selection by title and abstract, and (2) selection by complete text. This process was performed by two researchers (T.C., C.C.), and a third one (J.R.) intervened in case of discrepancies. This phase took place in January 2025.
2.5. PHASE 5: Evaluation of the Study Quality
The evaluation of the studies was performed by two researchers (C.C., T.C.) following the Mixed Methods Appraisal Tool (MMAT) [22] evaluation criteria for quantitative studies. This decision was made based on the possibility of the different nature of the quantitative studies included, which could be purely quantitative or mixed with quantitative data. The research team defined scores depending on the answer: Yes (25 points), Partial (10 points), and No (0 points); and four qualitative items of categorization were detailed: (a) High: 100 points, (b) moderate: 85 points, (c) low: 70 points, and (d) very low: less than 70 points. With a maximum score of 100 and a minimum of 0. Thus, the higher the score, the higher the methodological quality.
The GRADE system was also used to classify the evidence into four levels: high, moderate, low, or very low, and considering factors such as the study design, the consistency of the results, and risk of bias (Supplementary Material S4). Whether or not the items with answers Yes, Partial, or No met the quality criteria was assessed. One point was awarded for a Yes answer and 0 points for a Partial answer, while 1 point was subtracted for a No answer. Four qualitative items of categorization were also detailed: (a) High: 5 points, (b) moderate: more than 3 points, (c) low: 2 points, and (d) very low: less than 2 points [23].
2.6. PHASE 6: Data Extraction
The data were extracted from the following dimensions:
- Basic: author, year, country.
- Methodological: general objective, study design (experimental and quasi-experimental), participants and context (age, sex, work-related aspects, environmental and housing conditions), and evaluation intervention (variable assessment method).
- Substantive: interventions (specific actions of the intervention), results (effect measurements), conclusions (narrative synthesis), GRADE.
This process was conducted by three researchers (T.C., C.C., J.R.) and subsequently reviewed by the entire research team (Supplementary Material S5).
2.7. PHASE 7: Analysis and Synthesis of the Pertinent Studies
The analysis was performed at four levels: (1) Identification of the studies, (2) main characteristics of the articles included, (3) article quality, and (4) interventions to prevent and mitigate dehydration. To provide recommendations based on published interventions for preventing and mitigating dehydration, a descriptive synthesis of the results was chosen. This approach was selected due to the high heterogeneity observed among the included studies, both in the context of intervention development and in the analyzed variables and applied protocols, which precluded a comparative statistical analysis of effectiveness. The synthesis was organized into three types of interventions (educational and behavioral interventions, cooling and prevention of heat stress interventions, and hydration interventions), as the method of result synthesis. Therefore, the findings are initially presented in tabular form, including the internal statistical results of each study (percentages, group comparison tests, among others) and their main conclusions. Subsequently, a detailed narrative presentation of each type of intervention was developed.
3. Results
3.1. Identification of the Studies
The search in the selected databases provided a result of 558 articles, of which 284 were duplicates. In the first phase, after reviewing the titles and abstracts, 243 articles were excluded, leaving 31 for their complete reading in the second phase. Ultimately, nine articles were found to meet the inclusion criteria for this analysis. The articles excluded did not meet the established criteria, due to aspects such as the lack of participating agricultural workers, work contexts in farms or other buildings, a lack of an intervention, or their classification as projects or editorials (Figure 1).
Figure 1.
Flowchart of the study selection process according to the PRISMA guidelines.
3.2. Characteristics of the Included Studies
The studies were performed in different countries in two continents (America and Asia): two in El Salvador, one in Guatemala, one in Nicaragua, three in the USA, one in Japan, and one in South Korea (Figure 2). The total number of participants was 2046 agricultural workers. One study [24] did not provide the demographic characteristics of the sample, another [25] did not provide specific information (young adults), and the remaining ones provided the mean age (25.4, 28.6, 38, 42, 30, 30.6, 33–35) [24,26,27,28,29,30,31]. Two studies specified sex [27,28], and were the only ones with a higher number of women (90% and 60%), as compared to others, which showed values of 40% [29], 16% [32] or inland 2% and coastland 23% [26].
Figure 2.
Geographical distribution of study sites [24,25,26,27,28,29,30,31,32].
Two studies conducted in the USA [29,30] detailed that the workers were immigrant Hispanics. It must be detailed that in one of these studies [29] only 8% of the workers spoke English aside from Spanish. Other authors [31] identified the workers as being native to the area.
The work took place outside in agriculture-related areas (fernery, nursery, field crop landscape, sugar mill, sugarcane harvest), and only two studies [28,33] simulated work situations in a laboratory (red pepper harvest, apple orchard). Only two studies identified the length of the workday, one with a mean of 49 h per week (SD 8.5) [30] and the other with a mean workday of 7:40 h [27].
As for the environmental conditions, the articles specified high temperatures. These indicated mean temperatures of 29.3 °C around 1 p.m. [26], from 29.5 to 32.9 °C (maximum of 31.7 and 36.4 °C) [24,31], and a higher mean temperature of 33.5 °C, ranging from 26.7 °C to 36.4 °C [29].
The housing conditions varied according to the studies. In two studies [24,26], the participants were transported in buses or trucks from their homes to the workplace, while in another [30], the workers lived close to the workplace, had previous experience in agriculture, and knew farmers and workers in the area. One study was mixed [31], with production workers from around the area and displaced sugarcane cutters who lived in dormitories in the mill itself. Lastly, some authors [29] detailed that 70% of the participants lived in shack-type dwellings, in a house (13%), or a trailer (18%).
Lastly, it must be detailed that all the included studies, with respect to their design, included one intervention: six experimental (two randomized and four non-randomized), and three quasi-experimental (two post-intervention and one pre-post intervention). Despite the type of design, this last cross-cutting study was included, as it described a specific intervention. Table 1 shows a summary of the data presented in the study according to the following characteristics: (a) basic, (b) methodological, and (c) substantive. In addition, considering the requirements by Aromataris et al. [18] with respect to Phase 8 (presentation and interpretation of the results), the level of evidence according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) [23] was included.
Table 1.
Summary of the characteristics of the studies.
3.3. Article Quality
The nine articles were analyzed according to the MMAT instrument, and the results found in Table 2 and Table 3 were included according to the type of design. At the global level, it must be noted that 55.56% (five out of nine) obtained a score of 100% (high quality) and 44.44% (four out of nine) obtained a score of 85% (moderate quality), with none of them obtaining a lower score.
Table 2.
Quantitative randomized controlled trials.
Table 3.
Quantitative non-randomized controlled, quasi-experimental.
3.4. Interventions for the Prevention and Mitigation of Dehydration
To enhance the synthesis of the gathered evidence, we have summarized the main findings from the studies included in Table 4, following the structure according to the GRADE approach. The table includes the number of studies, total sample size, observed effects, and a qualitative confidence assessment—based on the CERQual principles—for each of the three intervention categories: Educational, Cooling/Thermal Stress Prevention, and Hydration.
Table 4.
Summary of Findings (SoF)—Interventions to prevent dehydration and heat stress among agricultural workers.
3.4.1. Educational Interventions
One study [29] provided training to six crew leaders on heat-related illnesses (HRI) and heat safety based on the OSHA guidelines. In addition, these crew leaders were equipped with a mobile application to monitor weather conditions and the heat index, enabling them to issue alerts and implement specific protective measures. The adaptive strategies introduced included adjusting work schedules and tasks, taking frequent breaks, wearing hats and light-colored clothing, increasing water intake, resting in shaded areas, and accessing air-conditioned environments during or after the workday to support recovery from heat exposure. However, the study did not establish a direct link between the training received by the crew leaders and the knowledge or behavior of the workers under their supervision. Along this line, the ADELANTE initiative [24] was developed in a platform to promote safe and productive work practices in the sugarcane industry and other sectors. The importance of comprehensive interventions to prevent chronic kidney disease of non-traditional origin (CKDnt) was highlighted.
Another study [31] evaluated the impact of an educational and behavioral intervention with sugarcane workers, both in production and in felling, based on an improved WERS (water, electrolytes, rest, and shade) program. For this, educational resources were used, such as in-person sessions, information posters, and urine color tables for the self-assessment of the degree of hydration. These tools, translated to Spanish and adapted to individuals with a low level of literacy, facilitated the early detection of dehydration signs and promoted preventive actions for avoiding the progression towards kidney failure.
Likewise, the impact of a two-component intervention program was explored [32]: (1) the implementation of a water, rest, and shade (WRS) program, and (2) the advice from consultants specialized in the sugarcane industry. The results underlined the importance of combining education with improvements in workplace conditions, such as the introduction of new cutting protocols and the use of an optimized machete with a more ergonomic and curved handle, which contributed to the reduction in fatigue and the improvement of the worker’s performance.
In addition, an intervention based on the WRS program was applied [26], which included individual backpacks with a capacity of 3 L, mobile rest areas, and programmed rest periods of 10–15 min every 1.5–2 h, along with an additional 45 min period of rest for lunch, representing 25% of the workday. This strategy led to a 25% increase in the consumption of water and a decrease in the symptoms related with heat stress and dehydration, underlining the effectiveness of educational and behavioral interventions, such as, for example, observing the color of urine as an indicator of dehydration, and the need to drink more water. The participants also indicated, in a qualitative manner, that their mood improved with the intervention. Nevertheless, the research assistants during the field work, and also in a qualitative manner, determined the need for more communication to overcome resistance to the WRS intervention.
3.4.2. Cooling and Prevention of Thermal Stress Interventions
One study [27] evaluated the effectiveness of different cooling devices to prevent agricultural workers from exceeding the threshold of a core body temperature of 38.0 °C. The results suggested that cooling bandanas could be a viable option for reducing the risk of hyperthermia as compared to cooling arm sleeves. The bandanas, fabricated with polyvinyl acetate materials and weighing less than a pound (~500 grs), are activated when they are submerged in water for one minute, and maintain their cooling effect for up to four hours. In addition, they can be placed on the head or neck, providing a light and easy-to-use option. On the contrary, although the cooling arm sleeves are also designed to reduce body temperature, they did not show the same efficacy. They tended to be made with heavier and bulkier materials, which can affect the mobility and comfort of the workers, limiting their adoption in agricultural environments.
Along this line, other studies [25,28] have indicated that the combination of multiple cooling devices, such as vests, scarves, and cooling systems integrated into clothing, can be an effective strategy for maintaining body temperature within safe ranges. In particular, the combination of a vest, scarf, and hat was shown to be the most efficient in maintaining body temperature below 38 °C and to reduce heart rate [25]. However, certain limitations were identified, such as the difficulty in maintaining the clothing items and skin dry, as well as the limited duration of the cooling effect of these systems [25]. In another study [28], clothing with integrated cooling technology was used, which helped mitigate heat stress and improve the comfort of the workers under extreme heat conditions.
3.4.3. Hydration Interventions
A recent study [30] showed a high acceptance of hydration backpacks among agricultural workers, which suggests that this intervention could be an efficient tool for promoting adequate hydration. The results indicated that the backpacks, commonly known as camelbacks, were well-received, with frequent use and an improvement in the intake of water reported by the workers. This continuous hydration strategy was also implemented in previous studies. In one of them [26], 3 L devices were used that were originally designed for the USA Special Forces for desert operations, while another study [32] used 3 L backpacks with accessible refills of up to 40 L. These antimicrobial devices only require hand cleaning and allow for a constant supply of water without restricting the worker’s movements. The results indicated that after the intervention, the group of workers who worked inside increased their intake of water from 5.1 L to 6.3 L, which was correlated with a reduction in dehydration symptoms, such as mouth dryness, and a reduction in urine volume. In addition, the workers reported better availability of fresh and clean water, while the researchers observed a higher clarity of the urine samples.
Another study [24] implemented a hydration strategy based on personal thermoses with 5 L of water per worker, access to refrigerators with fresh water, and the administration of envelopes with an electrolyte solution of 300 mL during the rest periods. Each portion contained 7 g of sugar, 50 mg of sodium chloride, and 20 mg of monopotassium phosphate per 100 mL. Additionally, other measures were optimized to improve adaptation to heat, such as an increase in the number of rest periods and the substitution of black tents for green ones, placed in shady areas. On its part, another study [31] evaluated a hydration program for sugarcane cutters that provided 16 L of water and 2.5 L of electrolyte solution per shift, ensuring an adequate provision of liquids to prevent dehydration and to mitigate the impact of heat stress on agricultural workers.
4. Discussion
The present systematic review provides an analysis of the interventions implemented to prevent dehydration or its risk in agricultural workers exposed to extreme heat and the risk of heat stress. Of the 558 articles that were initially considered, only nine were selected, as most of the studies were observational without an intervention, were centered on different populations, or did not address other health problems related to agricultural workers. No studies were selected that were published in Europe or Africa. In general terms, the available evidence presents a notable heterogeneity in the study designs, the populations studied, and the specific interventions evaluated.
The working conditions varied according to the geographical context, as shown by studies from the USA [27,29,30] and other regions. In the USA, the OSHA regulates occupational exposure to heat at the state level, establishing reductions during the workday when the temperatures are above 30 °C, as well as other safety measures [30,31]. The regional temperature variability has a direct impact on occupational health, as evidenced by findings from this study, in line with others [13]. This underlines the vulnerability of agricultural workers in tropical and sub-tropical areas, where heat stress and dehydration are significant risks. In addition, the relationship between global warming and the increase in occupational heat stress has been documented, highlighting the need for adapted regulations [13].
The evidence [24,29,31,32] suggests that the educational interventions on heat-related risks and safe practices significantly improve knowledge and work behaviors. Likewise, the importance of continuous training on high outdoor temperature safety is highlighted, especially for less experienced workers, in agreement with other studies [35,36]. Education and awareness programs, along with specific initiatives such as WERS and WER, have demonstrated, through the monitoring of diverse biomarkers (serum creatinine, urine osmolality, serum albumin, eGFR, WBST, and other measurements of temperature) to reduce the impact of heat in vulnerable populations, mitigating the adverse effects on health, especially dehydration and kidney problems [24,31,32]. The high prevalence of kidney problems and dehydration is a recurring finding in the literature [3,4,5,6,7,8]. However, the sustainability of these interventions and their ability to generate lasting changes require more research. For these strategies to be effective, it is fundamental for individuals to perceive their benefits, which can be promoted through public regulations and policies [37]. In addition, promoting health literacy must consider educational and cultural factors, especially in migrant populations with a low level of education [38].
On the one hand, the need to establish CKDu screening protocols and the monitoring of biomarkers is underlined, aside from the evaluation of other health conditions in agricultural workers [24]. On the other hand, monitoring biomarkers and health controls may be challenging due to cultural and social barriers, and difficult access to the health system. A study conducted in 2021 [39] on migrant agricultural workers pointed out that the lack of support staff or independent translators forces workers to depend on their employers to communicate with the doctors, which compromises their privacy and quality of care. This can lead to delays in the treatments, workplace retaliation, and a growing lack of trust in the health system. In addition, many workers perceive that health professionals are not aware of their precarious work conditions, which aggravates their vulnerability and makes access to adequate care more difficult.
The literature reviewed [25,27,28] shows the importance of body cooling to mitigate heat stress in agricultural workers, although there are discrepancies on the efficiency of different devices and their physiological mechanisms. The combination of cooling strategies has been demonstrated to be key in maintaining body temperature and reducing the cardiovascular load [25,28]. In particular, cooling bandanas could be promising, although their long-term effectiveness requires more research [27]. However, the implementation of these devices in rural and jungle areas has some limitations, such as the availability of electricity, logistic difficulties for their distribution, and acceptance by the workers due to factors such as the weight or interference in work tasks. In a qualitative study in 2021 [34], agricultural workers in Florida used cooling devices during their workday outdoors. The cooling bandanas were valued positively, while the arm sleeves were uncomfortable and heavy when they melted.
Hydration through oral intake is fundamental for maintaining body temperature, especially in hot climates and during physical activity. Sweating acts as a key cooling mechanism, but if the water lost is not adequately replenished, it can lead to dehydration, which increases the internal body temperature [40]. Thus, the evidence highlights the importance of guaranteeing water as the main liquid and electrolytes as part of comprehensive strategies, which may include rest in shady areas and education on heat-related risks [10,26,27,31,32]. These interventions have been shown to improve hydration and kidney function, and to reduce heat stress.
The optimum intake of water as the main liquid for hydration varies among studies [10,15], with a recommended amount ranging from 0.8 L/h to 250–300 mL/h, accompanied by rest in shaded areas. In addition, a warning is given about the consumption of drinks with a high content of fructose, due to its relationship with a risk of acute kidney injury [41].
Hydration systems, such as hydration backpacks, have been shown to be effective for maintaining adequate levels of hydration, with a mean consumption of 4.8 L/day in agricultural workers [30] and an increase in hydration of 25% [26]. Nevertheless, their weight can affect performance and the user’s comfort [42]. Alternatively, electrolyte-containing pens can prevent hyponatremia and improve hydration [24]. However, more research is needed on exposure to heat and dehydration, and the possible protective effect of the consumption of electrolyte solutions [4,43].
These interventions, such as access to water and accessible hydration systems at the workplace, are not only effective, but are also easy to implement in diverse agricultural contexts. Their simplicity and viability make them key strategies for mitigating the risks associated to heat stress and dehydration for agricultural workers, especially in environments with high temperatures and vulnerable populations. These hydration guidelines must be planned considering accessibility to water and its quality, as well as the influence of social factors and related power structures [14].
To optimize protection against heat, the combination of hydration with acclimation, adequate clothing, and structured pauses is recommended [13,41]. Some studies [26,29,31,32] suggest implementing three 20-min breaks and a longer break of 60 min for eating in shaded areas. It must be detailed that the studies included in the present review did not address the most adequate type of clothing for agricultural workers. Nevertheless, clothing has an influence on thermal regulation when modifying heat exchange. To minimize heat stress, it must be breathable, with a low capacity to isolate and absorb sweat. In addition, the reflective properties of the material are key aspects in sunny environments, and the ventilation between the skin and the item of clothing favors the dissipation of heat [44].
Lastly, it is essential to highlight that heat stress and dehydration are complex problems that require a comprehensive and coordinated approach to prevent them. The combination of educational strategies, hydration, cooling, and improvement in workplace conditions, such as adequate rest, access to potable water, and shaded areas, is fundamental to safeguard the health of agricultural workers. These interventions must be multidisciplinary and include the active participation of the workers, promoting collaboration between agencies, agricultural communities, and local authorities, with the potential for influencing public policies [38]. The interaction between workplace and environmental conditions must be a key factor in the formulation of stricter policies that not only regulate access to preventive measures, but also guarantee safe and healthy work environments to mitigate the risks of heat stress and dehydration. In addition, it is crucial to conduct additional studies to assess the sustainability and impact of these strategies in different agricultural and environmental contexts, guaranteeing their long-term effectiveness.
Limitations
The limited number of available articles and their heterogeneity made it impossible to perform an effectiveness analysis such as a meta-analysis. The studies themselves suggest conducting additional research to assess their effectiveness. The certainty of the evidence regarding the effectiveness of interventions to prevent dehydration was moderate, primarily due to imprecision in some small studies and inconsistency in the results across different climatic contexts. The geographical and cultural contexts of the studies varied significantly, which may influence the applicability of the findings to other regions. The differences in environmental conditions, cultural practices, and socioeconomic factors should be considered when interpreting the results. The bias associated with the languages selected as an inclusion criterion must also be detailed, as studies from other geographical areas could have been excluded. In fact, studies were identified that were written in Korean and other languages that were not considered in the analysis. This language bias may have excluded relevant studies that could have provided additional insights into the interventions for preventing dehydration and heat stress.
In addition, the lack of studies with a larger sample and more robust designs restricts the ability to generalize the findings. Some studies included small sample sizes and did not provide detailed demographic information about the participants. The lack of comprehensive data on age, sex, and other relevant characteristics may affect the interpretation of the results and the understanding of how different interventions impact various subgroups of agricultural workers. Other limitations of the analysis include factors such as a gender perspective, cultural influences, and the level of education of the participants, which could have had an influence on the results. The educational background and cultural practices of the participants can affect their perception and adoption of the interventions. Likewise, elements related to the medical history, such as existing chronic or acute conditions, must also be considered. Pre-existing health conditions, such as chronic kidney disease or other comorbidities, can influence the outcomes of the interventions and should be accounted for in future research.
5. Conclusions
The current evidence supports a multifaceted strategy that integrates educational efforts on hydration with improvements in workplace conditions to prevent dehydration and heat stress among agricultural workers. These interventions are significantly more effective when actively supported and facilitated by employers.
Behavioral strategies—such as scheduled rest breaks and access to shaded areas—require structural changes in the work environment. While worker education remains essential, it is insufficient without the provision of practical tools and resources by employers. The combination of education and tangible workplace modifications, including access to potable water and cooling equipment, is critical for protecting workers’ health.
Equipment-based interventions, such as cooling bandanas and hydration backpacks, have demonstrated particular effectiveness; for example, cooling bandanas were shown to significantly reduce the risk of hyperthermia. Although personal cooling systems are promising, further research is needed to determine the most suitable devices, particularly considering contextual limitations such as infrastructure. Employer engagement in providing resources and ensuring a safe work environment is vital. Ultimately, reducing heat-related risks in agriculture requires coordinated, sustained efforts from all stakeholders.
Supplementary Materials
The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/healthcare13111232/s1, Supplementary Material S1: PRISMA checklist; Supplementary Material S2: FINER criteria adapted to the study; Supplementary Material S3: Searching strategy; Supplementary Material S4: GRADE Assessment; Supplementary Material S5: Handling missing data.
Author Contributions
J.R.: conceptualization, data review, data analyses, writing—reviewing and editing, writing—original draft, and reviewing and editing; supervision. T.C.: conceptualization, methodology, data review and data analyses, writing—original draft, writing—reviewing and editing; C.C.: methodology, writing—original draft, writing—reviewing; M.S.-O., A.E. and A.L.S.: data analyses, and writing—reviewing and editing; C.C.-P. and G.T.-N.: conceptualization, methodology, and data review. All authors have read and agreed to the published version of the manuscript.
Funding
This research was supported by the Department of Research and Universities, the Department of Climate Action, Food and Rural Agenda, and the Climate Fund of the Generalitat de Catalunya (Project Code: 2023 CLIMA 00047).
Institutional Review Board Statement
This study is part of the WP Temporers (agricultural workers) of Project Code: 2023 CLIMA 00047, approved by the Ethics Committee for Research Involving Medicinal Products (CEIm, by its initials in Spanish) of the Arnau de Vilanova University Hospital (Lleida, Spain) (CEIC-3095, approved on 17 June 2024).
Informed Consent Statement
Not applicable.
Data Availability Statement
The data analyzed during the current study are not publicly available due to privacy restrictions, but are available from the corresponding authors on reasonable request.
Acknowledgments
We would like to thank Mario Font for the translation of the article.
Use of Artificial Intelligence
During the preparation of this manuscript, the authors used [https://copilot.microsoft.com/] (URL accessed on 6 May 2025) as a source of inspiration for generating graphic ideas. However, the final creation of the graphics was carried out directly by the authors themselves, who have reviewed and edited the content and take full responsibility for this publication.
Conflicts of Interest
The authors declare no conflicts of interest.
Abbreviations
The following abbreviations are used in this manuscript:
| CKDnt | Chronic kidney disease of non-traditional origin |
| CKDu | Chronic kidney disease of unknown origin |
| eGFR | Estimated glomerular filtration rate |
| FINER | Feasible, Interesting, Novel, Ethical, and Relevant |
| GRADE | Grading of Recommendations, Assessment, Development and Evaluation |
| HRI | Heat-related illnesses |
| IKI | Incident kidney injury |
| JBI | Joanna Briggs Institute |
| MeSH | Medical Subject Headings |
| MMAT | Mixed Methods Appraisal Tool |
| OSHA | Occupational Safety and Health Administration |
| PICO | Population, Intervention, Comparison, Outcomes |
| PRISMA | Preferred Reporting Items for Systematic Reviews and Meta-Analyses |
| SDG | Sustainable Development Goals |
| WBGT | Wet bulb globe temperature |
| WERS | Water, electrolytes, rest, shade |
| WRS | Water, rest, shade |
References
- Gao, C.; Kuklane, K.; Östergren, P.-O.; Kjellstrom, T. Occupational heat stress assessment and protective strategies in the context of climate change. Int. J. Biometeorol. 2018, 62, 359–371. [Google Scholar] [CrossRef] [PubMed]
- Moreno Martín, G.; Inglés Torruella, J. Occupational health impact of exposure to extreme heat: A systematic review. Rev. Habanera Cienc. Médicas 2023, 22, e5328. [Google Scholar]
- Boonruksa, P.; Maturachon, T.; Kongtip, P.; Woskie, S. Heat Stress, Physiological Response, and Heat-Related Symptoms among Thai Sugarcane Workers. Int. J. Environ. Res. Public Health 2020, 17, 6363. [Google Scholar] [CrossRef] [PubMed]
- Laws, R.L.; Brooks, D.R.; Amador, J.J.; Weiner, D.E.; Kaufman, J.S.; Ramírez-Rubio, O.; Riefkohl, A.; Scammell, M.K.; López-Pilarte, D.; Marcel Sánchez, J.; et al. Changes in kidney function among Nicaraguan sugarcane workers. Int. J. Occup. Environ. Health 2015, 21, 241–250. [Google Scholar] [CrossRef]
- Petropoulos, Z.E.; Keogh, S.A.; Jarquín, E.; López-Pilarte, D.; Velázquez, J.J.A.; García-Trabanino, R.; Sánchez, M.R.A.; Guevara, R.; Gruener, A.; Allen, D.R.; et al. Heat stress and heat strain among outdoor workers in El Salvador and Nicaragua. J. Expo. Sci. Environ. Epidemiol. 2023, 33, 622–630. [Google Scholar] [CrossRef]
- Pogačar, T.; Črepinšek, Z.; Bogataj, L.K.; Nybo, L. Comprehension of climatic and occupational heat stress amongst agricultural advisers and workers in Slovenia. Acta Agric. Slov. 2017, 109, 545–554. [Google Scholar] [CrossRef]
- Torres, C.; Aragón, A.; González, M.; López, I.; Jakobsson, K.; Elinder, C.-G.; Lundberg, I.; Wesseling, C. Decreased Kidney Function of Unknown Cause in Nicaragua: A Community-Based Survey. Am. J. Kidney Dis. 2010, 55, 485–496. [Google Scholar] [CrossRef]
- Wagoner, R.S.; López-Gálvez, N.I.; de Zapien, J.G.; Griffin, S.C.; Canales, R.A.; Beamer, P.I. An Occupational Heat Stress and Hydration Assessment of Agricultural Workers in North Mexico. Int. J. Environ. Res. Public Health 2020, 17, 2102. [Google Scholar] [CrossRef]
- Peraza, S.; Wesseling, C.; Aragon, A.; Leiva, R.; García-Trabanino, R.A.; Torres, C.; Jakobsson, K.; Elinder, C.G.; Hogstedt, C. Decreased Kidney Function Among Agricultural Workers in El Salvador. Am. J. Kidney Dis. 2012, 59, 531–540. [Google Scholar] [CrossRef]
- Morris, N.B.; Ravanelli, N.; Chaseling, G.K. Correction: The effect of alcohol consumption on human physiological and perceptual responses to heat stress: A systematic scoping review. Environ. Health 2024, 23, 73. [Google Scholar] [CrossRef]
- Garcia-Trabanino, R.; Jarquin, E.; Wesseling, C.; Johnson, R.J.; Gonzalez-Quiroz, M.; Weiss, I.; Glaser, J.; Vindell, J.J.; Stockfelt, L.; Roncal, C.; et al. Heat stress, dehydration, and kidney function in sugarcane cutters in EI Salvador—A cross-shift study of workers at risk of Mesoamerican nephropathy. Environ. Res. 2015, 142, 746–755. [Google Scholar] [CrossRef]
- Ramirez-Rubio, O.; Brooks, D.R.; Amador, J.J.; Kaufman, J.S.; E Weiner, D.; Scammell, M.K. Chronic kidney disease in Nicaragua: A qualitative analysis of semi-structured interviews with physicians and pharmacists. BMC Public Health 2013, 13, 350. [Google Scholar] [CrossRef]
- Habibi, P.; Razmjouei, J.; Moradi, A.; Mahdavi, F.; Fallah-Aliabadi, S.; Heydari, A. Climate change and heat stress resilient outdoor workers: Findings from systematic literature review. BMC Public Health 2024, 24, 1711. [Google Scholar] [CrossRef]
- Mizelle, E.; Larson, K.L.; Bolin, L.P.; Kearney, G.D. Fluid Intake and Hydration Status Among North Carolina Farmworkers: A Mixed Methods Study. Work. Health Saf. 2022, 70, 532–541. [Google Scholar] [CrossRef]
- Sankar, S.K.; Vijayalakshmi, P.; Krishnan, S.; Shanmugam, R.; Kamalakkanan, L.P.; Venugopal, V. Effectiveness of heat stress interventions among outdoor workers: A protocol paper. Front. Public Health 2024, 12, 1477186. [Google Scholar] [CrossRef]
- Ferreira-Pêgo, C.; Nissensohn, M.; Kavouras, S.A.; Babio, N.; Serra-Majem, L.; Águila, A.M.; Mauromoustakos, A.; Pérez, J.Á.; Salas-Salvadó, J. Beverage Intake Assessment Questionnaire: Relative Validity and Repeatability in a Spanish Population with Metabolic Syndrome from the PREDIMED-PLUS Study. Nutrients 2016, 8, 475. [Google Scholar] [CrossRef]
- Page, M.J.; McKenzie, J.E.; Bossuyt, P.M.; Boutron, I.; Hoffmann, T.C.; Mulrow, C.D.; Shamseer, L.; Tetzlaff, J.M.; Akl, E.A.; Brennan, S.E.; et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ 2021, 372, n71. [Google Scholar] [CrossRef]
- Aromataris, E.; Lockwood, C.; Porritt, K.; Pilla, B.; Jordan, Z. (Eds.) JBI Manual for Evidence Synthesis [Internet]. JBI. 2024. Available online: https://jbi-global-wiki.refined.site/space/MANUAL (accessed on 21 January 2025).
- Fandino, W. Formulating a good research question: Pearls and pitfalls. Indian J. Anaesth. 2019, 63, 611–616. [Google Scholar] [CrossRef] [PubMed]
- Sánchez-Martín, M.; Plana, M.P.; Gea, A.I.P.; Navarro-Mateu, F. And, at first, it was the research question… The PICO, PECO, SPIDER and FINER formats. ESPIRAL Cuad. Profr. 2023, 16, 126–136. [Google Scholar]
- Ouzzani, M.; Hammady, H.; Fedorowicz, Z.; Elmagarmid, A. Rayyan—A web and mobile app for systematic reviews. Syst. Rev. 2016, 5, 210. [Google Scholar] [CrossRef]
- Hong, Q.N.; Gonzalez-Reyes, A.; Pluye, P. Improving the usefulness of a tool for appraising the quality of qualitative, quantitative and mixed methods studies, the Mixed Methods Appraisal Tool (MMAT). J. Eval. Clin. Pr. 2018, 24, 459–467. [Google Scholar] [CrossRef] [PubMed]
- Aguayo-Albasini, J.L.; Flores-Pastor, B.; Soria-Aledo, V. Sistema GRADE: Clasificación de la calidad de la evidencia y graduación de la fuerza de la recomendación. Cir. Esp. 2014, 92, 82–88. [Google Scholar] [CrossRef] [PubMed]
- Glaser, J.; Hansson, E.; Weiss, I.; Wesseling, C.; Jakobsson, K.; Ekström, U.; Apelqvist, J.; Lucas, R.; Monge, E.A.; Peraza, S.; et al. Preventing kidney injury among sugarcane workers: Promising evidence from enhanced workplace interventions. Occup. Environ. Med. 2020, 77, 527–534. [Google Scholar] [CrossRef] [PubMed]
- Choi, J.-W.; Kim, M.-J.; Lee, J.-Y. Alleviation of Heat Strain by Cooling Different Body Areas During Red Pepper Harvest Work at WBGT 33 °C. Ind. Health 2008, 46, 620–628. [Google Scholar] [CrossRef]
- Bodin, T.; García-Trabanino, R.; Weiss, I.; Jarquín, E.; Glaser, J.; Jakobsson, K.; Lucas, R.A.I.; Wesseling, C.; Hogstedt, C.; Wegman, D.H. Intervention to reduce heat stress and improve efficiency among sugarcane workers in El Salvador: Phase 1. Occup. Environ. Med. 2016, 73, 409–416. [Google Scholar] [CrossRef]
- Chicas, R.; Xiuhtecutli, N.; Elon, L.; Scammell, M.K.; Steenland, K.; Hertzberg, V.; McCauley, L. Cooling Interventions Among Agricultural Workers: A Pilot Study. Work. Health Saf. 2020, 69, 315–322. [Google Scholar] [CrossRef]
- Hayashi, C.; Tokura, H. Improvement of thermophysiological stress in participants wearing protective clothing for spraying pesticide, and its application in the field. Int. Arch. Occup. Environ. Health 2000, 73, 187–194. [Google Scholar] [CrossRef]
- Luque, J.S.; Becker, A.; Bossak, B.H.; Grzywacz, J.G.; Tovar-Aguilar, J.A.; Guo, Y. Knowledge and Practices to Avoid Heat-Related Illness among Hispanic Farmworkers along the Florida-Georgia Line. J. Agromed. 2020, 25, 190–200. [Google Scholar] [CrossRef]
- Mizelle, E.; Modly, L.A.; Smith, D.J. Farmworker Acceptability of Backpack Hydration Systems. J. Agromed. 2024, 29, 477–485. [Google Scholar] [CrossRef]
- Sorensen, C.J.; Krisher, L.; Butler-Dawson, J.; Dally, M.; Dexter, L.; Asensio, C.; Cruz, A.; Newman, L.S. Workplace Screening Identifies Clinically Significant and Potentially Reversible Kidney Injury in Heat-Exposed Sugarcane Workers. Int. J. Environ. Res. Public Health 2020, 17, 8552. [Google Scholar] [CrossRef]
- Wegman, D.H.; Apelqvist, J.; Bottai, M.; Ekström, U.; García-Trabanino, R.; Glaser, J.; Hogstedt, C.; Jakobsson, K.; Jarquín, E.; Lucas, R.A.I.; et al. Intervention to diminish dehydration and kidney damage among sugarcane workers. Scand. J. Work. Environ. Health 2017, 44, 16–24. [Google Scholar] [CrossRef] [PubMed]
- Choi, J.S. Analysis of Toxicity in Endometrial Cells Exposed Phthalate. Korean J. Clin. Lab. Sci. 2019, 51, 86–92. [Google Scholar] [CrossRef]
- Chicas, R.; Xiuhtecutli, N.; Dickman, N.E.; Flocks, J.; Scammell, M.K.; Steenland, K.; Hertzberg, V.; McCauley, L. Cooling Interventions Among Agricultural Workers: Qualitative Field-Based Study. Hisp. Health Care Int. 2021, 19, 174–181. [Google Scholar] [CrossRef]
- Razzak, J.A.; Agrawal, P.; Chand, Z.; Quraishy, S.; Ghaffar, A.; A Hyder, A. Impact of community education on heat-related health outcomes and heat literacy among low-income communities in Karachi, Pakistan: A randomised controlled trial. BMJ Glob. Health 2022, 7, e006845. [Google Scholar] [CrossRef]
- Reismann, L.; Weber, A.; Leitzmann, M.; Jochem, C. Climate-specific health literacy and medical advice: The potential for health co-benefits and climate change mitigation. An exploratory study. J. Clim. Change Health 2021, 4, 100072. [Google Scholar] [CrossRef]
- Semenza, J.C.; Hall, D.E.; Wilson, D.J.; Bontempo, B.D.; Sailor, D.J.; George, L.A. Public Perception of Climate Change: Voluntary Mitigation and Barriers to Behavior Change. Am. J. Prev. Med. 2008, 35, 479–487. [Google Scholar] [CrossRef]
- Coman, M.A.; Marcu, A.; Chereches, R.M.; Leppälä, J.; Broucke, S.V.D. Educational Interventions to Improve Safety and Health Literacy Among Agricultural Workers: A Systematic Review. Int. J. Environ. Res. Public Health 2020, 17, 1114. [Google Scholar] [CrossRef]
- Colindres, C.; Cohen, A.; Caxaj, C.S. Migrant Agricultural Workers’ Health, Safety and Access to Protections: A Descriptive Survey Identifying Structural Gaps and Vulnerabilities in the Interior of British Columbia, Canada. Int. J. Environ. Res. Public Health 2021, 18, 3696. [Google Scholar] [CrossRef]
- Popkin, B.M.; D’Anci, K.E.; Rosenberg, I.H. Water, hydration, and health. Nutr. Rev. 2010, 68, 439–458. [Google Scholar] [CrossRef]
- Masoud, A.; McKenna, Z.J.; Li, Z.; Deyhle, M.R.; Mermier, C.M.; Schlader, Z.J.; Amorim, F.T. Strategies to mitigate acute kidney injury risk during physical work in the heat. Am. J. Physiol. Physiol. 2024, 326, F499–F510. [Google Scholar] [CrossRef] [PubMed]
- Waddington, G.S.; Dickson, T.J.; Trathen, S.D.; Adams, R.D.; Johnson, R.J.; Shealy, J.; Senner, V.; Dean, S.W. Hydration Packs Modify Professional Skiers Hydration Levels in All Day Skiing: A Randomized Controlled Trial. J. ASTM Int. 2010, 7, 225. [Google Scholar] [CrossRef]
- Klemens, C.A.; Brands, M.W.; Staruschenko, A. Postprandial effects on electrolyte homeostasis in the kidney. Am. J. Physiol.-Ren. Physiol. 2019, 317, F1405–F1408. [Google Scholar] [CrossRef] [PubMed]
- Périard, J.D.; Eijsvogels, T.M.H.; Daanen, H.A.M. Exercise under heat stress: Thermoregulation, hydration, performance implications, and mitigation strategies. Physiol. Rev. 2021, 101, 1873–1979. [Google Scholar] [CrossRef] [PubMed]
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