Trends and Geographic Variabilities in Benzodiazepines Prescription in Primary Care to Older Adults: A 3-Year Population-Based Ecological Study in Portugal
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Study Population
2.2. Benzodiazepines Studied
2.3. Data Source
2.4. Statistical Analysis
3. Results
3.1. Study Population
3.2. Total Benzodiazepine Prescription Share (%)
3.2.1. Benzodiazepine Prescription by Gender
3.2.2. Analysis of Most Prescribed Benzodiazepines Drugs
3.3. Trends and Change in the Prescription Rate of Benzodiazepines
3.4. Geographic Variation in DID Benzodiazepine Prescription to Older Adults
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Alentejo | Algarve | Norte | Centro | LVT | National | |
---|---|---|---|---|---|---|
F/M | 3.0 | 2.6 | 2.4 | 2.7 | 2.8 | 2.7 |
Benzodiazepine | 2019 (DID) | 2020 (DID) | 2021 (DID) | ∆ 2021–2019 (DID) | ∆ 2021–2019 (%) |
---|---|---|---|---|---|
ARSN | |||||
Alprazolam (N05BA12) | 63.1 | 72.0 | 71.9 | 8.9 | 14.1% |
Lorazepam (N05BA06) | 71.6 | 80.9 | 80.8 | 9.2 | 12.8% |
Diazepam (N05BA01) | 18.1 | 20.2 | 19.4 | 1.3 | 7.2% |
Ethyl loflazepate (N05BA18) | 16.9 | 13.4 | 18.2 | 1.3 | 7.4% |
Bromazepam (N05BA08) | 11.6 | 12.8 | 12.4 | 0.8 | 6.8% |
ARSC | |||||
Alprazolam (N05BA12) | 78.8 | 79.5 | 75.4 | −3.4 | −4.4% |
Lorazepam (N05BA06) | 65.1 | 65.9 | 63.6 | −1.5 | −2.2% |
Diazepam (N05BA01) | 24.6 | 24.2 | 21.7 | −2.9 | −11.6% |
Ethyl loflazepate (N05BA18) | 12.9 | 8.8 | 12.0 | −0.9 | 7.0% |
Bromazepam (N05BA08) | 9.3 | 9.2 | 8.6 | −0.7 | −7.2% |
ARSALE | |||||
Alprazolam (N05BA12) | 52.9 | 55.8 | 54.7 | 1.7 | 3.3% |
Lorazepam (N05BA06) | 34.2 | 36.9 | 36.2 | 2.1 | 6.0% |
Diazepam (N05BA01) | 20.4 | 20.8 | 18.5 | −1.9 | −9.3% |
Ethyl loflazepate (N05BA18) | 10.7 | 7.3 | 11.4 | 0.7 | 6.6% |
Bromazepam (N05BA08) | 11.0 | 11.5 | 10.9 | −0.1 | −1.2% |
ARSALG | |||||
Alprazolam (N05BA12) | 37.5 | 40.3 | 36.8 | −0.7 | −1.8% |
Lorazepam (N05BA06) | 25.6 | 26.5 | 1.5 | −0.3 | −1.0% |
Diazepam (N05BA01) | 11.4 | 11.4 | 10.1 | −1.2 | −10.9% |
Ethyl loflazepate (N05BA18) | 9.9 | 7.0 | 9.8 | −0.1 | −0.8% |
Bromazepam (N05BA08) | 10.7 | 11.4 | 10.3 | −0.4 | −4.0% |
ARSLVT | |||||
Alprazolam (N05BA12) | 50.4 | 53.1 | 56.3 | 6.0 | 11.9% |
Lorazepam (N05BA06) | 36.1 | 37.6 | 39.4 | 3.2 | 8.9% |
Diazepam (N05BA01) | 19.6 | 19.6 | 19.4 | −0.2 | −0.8% |
Ethyl loflazepate (N05BA18) | 13.9 | 10.2 | 15.9 | 2.0 | 14.2% |
Bromazepam (N05BA08) | 11.9 | 12.2 | 12.7 | 0.8 | 6.8% |
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Tavares, A.B.; Placido, A.I.; Rodrigues, D.A.; Morgado, M.; Figueiras, A.; Herdeiro, M.T.; Roque, F. Trends and Geographic Variabilities in Benzodiazepines Prescription in Primary Care to Older Adults: A 3-Year Population-Based Ecological Study in Portugal. Healthcare 2022, 10, 1342. https://doi.org/10.3390/healthcare10071342
Tavares AB, Placido AI, Rodrigues DA, Morgado M, Figueiras A, Herdeiro MT, Roque F. Trends and Geographic Variabilities in Benzodiazepines Prescription in Primary Care to Older Adults: A 3-Year Population-Based Ecological Study in Portugal. Healthcare. 2022; 10(7):1342. https://doi.org/10.3390/healthcare10071342
Chicago/Turabian StyleTavares, Ana Bárbara, Ana Isabel Placido, Daniela Almeida Rodrigues, Manuel Morgado, Adolfo Figueiras, Maria Teresa Herdeiro, and Fátima Roque. 2022. "Trends and Geographic Variabilities in Benzodiazepines Prescription in Primary Care to Older Adults: A 3-Year Population-Based Ecological Study in Portugal" Healthcare 10, no. 7: 1342. https://doi.org/10.3390/healthcare10071342