Association between Periodontitis and Chronic Rhinosinusitis Involving Maxillary Sinus Measured by Lund Mackay Staging System
Abstract
:1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Hamilos, D.L. Chronic rhinosinusitis: Epidemiology and medical management. J. Allergy Clin. Immunol. 2011, 128, 693–707. [Google Scholar] [CrossRef]
- Kim, S.M. Definition and management of odontogenic maxillary sinusitis. Maxillofac. Plast. Reconstr. Surg. 2019, 41, 13. [Google Scholar] [CrossRef] [Green Version]
- Bernardi, S.; Scarsella, S.; Di Fabio, D.; Oliva, A.; Di Girolamo, M.; Continenza, M.A.; Cutilli, T. Giant follicular cysts extended in pterygo-maxillary fossa, antro-naso-ethmoidal and orbital space associated to exophtalmos and diplopia in young patients. Oral Maxillofac. Surg. Case 2018, 4, 17–22. [Google Scholar] [CrossRef]
- Trimarchi, M.; Vinciguerra, A.; Galli, A.; CapparÃ, P.; Vinci, R.; Bussi, M. Management of upper odontogenic infections and the role of multidisciplinary treatment. J. Osseointegration 2019, 11, 548–552. [Google Scholar]
- Tanasiewicz, M.; Bubilek-Bogacz, A.; Twardawa, H.; Skucha-Nowak, M.; Szklarski, T. Foreign body of endodontic origin in the maxillary sinus. J. Dent. Sci. 2017, 12, 296–300. [Google Scholar] [CrossRef] [Green Version]
- Tanna, N.; Awal, D.; Eyeson, J. An unusual case of Sinusitis–foreign body in the maxillary antrum. Oral Surg. 2019, 12, 118–122. [Google Scholar] [CrossRef]
- Küçükkurt, S.; Tükel, H.C.; Murat, Ö. Removal of displaced metallic foreign bodies from maxillary sinus: Two cases. J. Dent. Fac. Ataturk Univ. 2018, 28, 396–399. [Google Scholar] [CrossRef]
- Stevens, W.W.; Lee, R.J.; Schleimer, R.P.; Cohen, N.A. Chronic rhinosinusitis pathogenesis. J. Allergy Clin. Immunol. 2015, 136, 1442–1453. [Google Scholar] [CrossRef] [Green Version]
- Kwon, T.; Lamster, I.B.; Levin, L. Current concepts in the management of periodontitis. Int. Dent. J. 2021, 71, 462–476. [Google Scholar] [CrossRef]
- Flemmig, T.F. Periodontitis. Ann. Periodontol. 1999, 4, 32–37. [Google Scholar] [CrossRef] [PubMed]
- Albandar, J.; Brunelle, J.; Kingman, A. Destructive periodontal disease in adults 30 years of age and older in the United States, 1988–1994. J. Periodontol. 1999, 70, 13–29. [Google Scholar] [CrossRef] [PubMed]
- Lechien, J.R.; Filleul, O.; Costa de Araujo, P.; Hsieh, J.W.; Chantrain, G.; Saussez, S. Chronic maxillary rhinosinusitis of dental origin: A systematic review of 674 patient cases. Int. J. Otolaryngol. 2014, 2014, 465173. [Google Scholar] [CrossRef] [Green Version]
- Keller, J.J.; Wu, C.S.; Lin, H.C. Chronic rhinosinusitis increased the risk of chronic periodontitis: A population-based matched-cohort study. Laryngoscope 2013, 123, 1323–1327. [Google Scholar] [CrossRef]
- Fokkens, W.J.; Lund, V.J.; Hopkins, C.; Hellings, P.W.; Kern, R.; Reitsma, S.; Toppila-Salmi, S.; Bernal-Sprekelsen, M.; Mullol, J.; Alobid, I. European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 2020, 58, 1–464. [Google Scholar] [CrossRef]
- Holbrook, E.H.; Brown, C.L.; Lyden, E.R.; Leopold, D.A. Lack of significant correlation between rhinosinusitis symptoms and specific regions of sinus computer tomography scans. Am. J. Rhinol. 2005, 19, 382–387. [Google Scholar] [CrossRef]
- Fokkens, W.J.; Lund, V.J.; Mullol, J.; Bachert, C.; Alobid, I.; Baroody, F.; Cohen, N.; Cervin, A.; Douglas, R.; Gevaert, P. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 2012, 50, 1–12. [Google Scholar] [CrossRef]
- Feres, M.; Teles, F.; Teles, R.; Figueiredo, L.C.; Faveri, M. The subgingival periodontal microbiota of the aging mouth. Periodontology 2000 2016, 72, 30–53. [Google Scholar] [CrossRef] [Green Version]
- Wahlin, Å.; Papias, A.; Jansson, H.; Norderyd, O. Secular trends over 40 years of periodontal health and disease in individuals aged 20–80 years in Jönköping, Sweden: Repeated cross-sectional studies. J. Clin. Periodontol. 2018, 45, 1016–1024. [Google Scholar] [CrossRef]
- Kassebaum, N.; Bernabé, E.; Dahiya, M.; Bhandari, B.; Murray, C.; Marcenes, W. Global burden of severe periodontitis in 1990–2010: A systematic review and meta-regression. J. Dent. Res. 2014, 93, 1045–1053. [Google Scholar] [CrossRef]
- Raitapuro-Murray, T.; Molleson, T.; Hughes, F. The prevalence of periodontal disease in a Romano-British population c. 200–400 AD. Br. Dent. J. 2014, 217, 459–466. [Google Scholar] [CrossRef]
- Sheiham, A. Oral health, general health and quality of life. Bull. World Health Organ. 2005, 83, 644. [Google Scholar] [PubMed]
- Brüllmann, D.D.; Schmidtmann, I.; Hornstein, S.; Schulze, R.K. Correlation of cone beam computed tomography (CBCT) findings in the maxillary sinus with dental diagnoses: A retrospective cross-sectional study. Clin. Oral Investig. 2012, 16, 1023–1029. [Google Scholar] [CrossRef] [PubMed]
- Shanbhag, S.; Karnik, P.; Shirke, P.; Shanbhag, V. Association between periapical lesions and maxillary sinus mucosal thickening: A retrospective cone-beam computed tomographic study. J Endod 2013, 39, 853–857. [Google Scholar] [CrossRef] [PubMed]
- Mathew, A.L.; Pai, K.M.; Sholapurkar, A.A. Maxillary sinus findings in the elderly: A panoramic radiographic study. J. Contemp. Dent. Pract. 2009, 10, 41–48. [Google Scholar]
- Kahveci, O.; Demirdal, U.; Yücedag, F.; Cerci, U. Patients with osteoporosis have higher incidence of sensorineural hearing loss. Clin. Otolaryngol. 2014, 39, 145–149. [Google Scholar] [CrossRef] [PubMed]
- Wuokko-Landén, A.; Blomgren, K.; Suomalainen, A.; Välimaa, H. Odontogenic causes complicating the chronic rhinosinusitis diagnosis. Clin. Oral Investig. 2021, 25, 947–955. [Google Scholar] [CrossRef]
- Wagaiyu, E.; Ashley, F. Mouthbreathing, lip seal and upper lip coverage and their relationship with gingival inflammation in 11–14 year-old schoolchildren. J. Clin. Periodontol. 1991, 18, 698–702. [Google Scholar] [CrossRef]
- Jacobson, L.; Linder-Aronson, S. Crowding and gingivitis: A comparison between mouthbreathers and nosebreathers. Eur. J. Oral Sci. 1972, 80, 500–504. [Google Scholar] [CrossRef]
- Kaur, M.; Sharma, R.K.; Tewari, S.; Narula, S.C. Influence of mouth breathing on outcome of scaling and root planing in chronic periodontitis. BDJ Open 2018, 4, 17039. [Google Scholar] [CrossRef] [Green Version]
- Preus, H.R.; Khanifam, P.; Kolltveit, K.; Mørk, C.; Gjermo, P. Periodontitis in psoriasis patients. A blinded, case-controlled study. Acta Odontol. Scand. 2010, 68, 165–170. [Google Scholar] [CrossRef]
- Kern, R.C.; Conley, D.B.; Walsh, W.; Chandra, R.; Kato, A.; Tripathi-Peters, A.; Grammer, L.C.; Schleimer, R.P. Perspectives on the etiology of chronic rhinosinusitis: An immune barrier hypothesis. Am. J. Rhinol. 2008, 22, 549–559. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Byun, S.H.; Min, C.; Park, I.S.; Kim, H.; Kim, S.K.; Park, B.J.; Choi, H.G.; Hong, S.J. Increased risk of chronic periodontitis in chronic rhinosinusitis patients: A longitudinal follow-up study using a national health-screening cohort. J. Clin. Med. 2020, 9, 1170. [Google Scholar] [CrossRef] [PubMed]
- Rajasekaran, K.; Seth, R.; Abelson, A.; Batra, P.S. Prevalence of metabolic bone disease among chronic rhinosinusitis patients treated with oral glucocorticoids. Am. J. Rhinol. Allergy 2010, 24, 215–219. [Google Scholar] [CrossRef]
- Bolger, W.E.; Leonard, D.; Dick, E.J., Jr.; Stierna, P. Gram negative sinusitis: A bacteriologic and histologic study in rabbits. Am. J. Rhinol. 1997, 11, 15–26. [Google Scholar] [CrossRef]
- Kocak, M.; Smith, T.L.; Smith, M.M. Bone involvement in chronic rhinosinusitis. Curr. Opin. Otolaryngol. Head Neck Surg. 2002, 10, 49–52. [Google Scholar] [CrossRef]
- Khalid, A.N.; Hunt, J.; Perloff, J.R.; Kennedy, D.W. The role of bone in chronic rhinosinusitis. Laryngoscope 2002, 112, 1951–1957. [Google Scholar] [CrossRef]
- Sanz, M.; Del Castillo, A.M.; Jepsen, S.; Gonzalez-Juanatey, J.R.; D’Aiuto, F.; Bouchard, P.; Chapple, I.; Dietrich, T.; Gotsman, I.; Graziani, F. Periodontitis and cardiovascular diseases: Consensus report. J. Clin. Periodontol. 2020, 47, 268–288. [Google Scholar] [CrossRef]
- de Sire, A.; Invernizzi, M.; Ferrillo, M.; Gimigliano, F.; Baricich, A.; Cisari, C.; De Marchi, F.; Foglio Bonda, P.L.; Mazzini, L.; Migliario, M. Functional status and oral health in patients with amyotrophic lateral sclerosis: A cross-sectional study. NeuroRehabilitation 2021, 48, 49–57. [Google Scholar] [CrossRef]
- Nwizu, N.; Wactawski-Wende, J.; Genco, R.J. Periodontal disease and cancer: Epidemiologic studies and possible mechanisms. Periodontology 2000 2020, 83, 213–233. [Google Scholar] [CrossRef]
- Ferrillo, M.; Migliario, M.; Roccuzzo, A.; Molinero-Mourelle, P.; Falcicchio, G.; Umano, G.R.; Pezzotti, F.; Foglio Bonda, P.L.; Calafiore, D.; de Sire, A. Periodontal disease and vitamin D deficiency in pregnant women: Which correlation with preterm and low-weight birth? J. Clin. Med. 2021, 10, 4578. [Google Scholar] [CrossRef]
Variables | Frequency | Percentage | |
---|---|---|---|
Gender | |||
Male | 163 | 40.9 | |
Female | 236 | 59.1 | |
Bone loss > 50% | |||
Present | 160 | 40.1 | |
Absent | 239 | 59.9 | |
Sinusitis | |||
Present | 280 | 70.2 | |
Absent | 119 | 29.8 | |
Sinusitis (right side) | |||
Normal | 172 | 43.1 | |
Partial opacity | 222 | 55.6 | |
Complete opacity | 5 | 1.3 | |
Sinusitis (left side) | |||
Normal | 176 | 44.1 | |
Partial opacity | 216 | 54.1 | |
Complete opacity | 7 | 1.8 | |
Periodontitis | |||
Present | 155 | 38.8 | |
Absent | 244 | 61.2 | |
Medical history | |||
Cancer | 1 | 0.3 | |
DM | 14 | 3.5 | |
HTN | 15 | 3.8 | |
Asthma | 8 | 2.0 | |
Hypothyroidism | 1 | 0.3 | |
kidney problem | 1 | 0.3 | |
Allergy | 1 | 0.3 | |
Hepatitis | 1 | 0.3 | |
DM+ HTN | 11 | 2.8 | |
DM+ Rheumatic fever | 1 | 0.3 | |
DM+ HTN+ thyroid+ Cholesterol | 1 | 0.3 | |
NAD | 343 | 86.0 |
Variables | CRS Present (n = 280) | CRS Absent (n = 119) | p | OR | CI | |
---|---|---|---|---|---|---|
Lower | Upper | |||||
Mean age (SD) | 48.89 (11.44) | 44.43 (11.39) | 0.096 | 0.980 | 0.957 | 1.004 |
Gender | 0.0001 * | 0.380 | 0.233 | 0.619 | ||
Male (%) | 133 (47.50) | 30 (25.20) | ||||
Female (%) | 147 (52.50) | 89 (74.80) | ||||
Bone loss > 50% | 0.143 | 0.451 | 0.156 | 1.308 | ||
Present (%) | 130 (46.40) | 30 (25.20) | ||||
Absent (%) | 150 (53.60) | 89 (74.80) | ||||
Medical history | 0.531 | 0.795 | 0.388 | 1.628 | ||
Present (%) | 44 (15.70) | 12 (10.10) | ||||
Absent (%) | 236 (84.30) | 107 (89.90) | ||||
Periodontitis | ||||||
Present (%) | 125 (44.60) | 30 (25.20) | 0.886 | 1.081 | 0.374 | 3.125 |
Absent (%) | 155 (55.40) | 89 (74.80) |
Variables | CRS Present (n = 280) | CRS Absent (n = 119) | p | OR | CI | |
---|---|---|---|---|---|---|
Lower | Upper | |||||
Gender | 0.0001 * | 0.371 | 0.229 | 0.603 | ||
Male (%) | 133 (47.50) | 30 (25.20) | ||||
Female (%) | 147 (52.50) | 89 (74.80) | ||||
Bone loss > 50% | 0.0001 * | 0.388 | 0.239 | 0.630 | ||
Present (%) | 130 (46.40) | 30 (25.20) | ||||
Absent (%) | 150 (53.60) | 89 (74.80) |
Variables | Bilateral CRS vs. Unilateral CRS | Bilateral CRS vs. No CRS | Unilateral CRS vs. No CRS | |||
---|---|---|---|---|---|---|
p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | |
Gender | 0.096 | 0.658 (0.402, 1.077) | 0.0001 * | 0.314 (0.186, 0.530) | 0.011 * | 0.476 (0.269, 0.843) |
Bone loss > 50% | 0.619 | 1.308 (0.455, 3.762) | 0.152 | 0.430 (0.136, 1.366) | 0.079 | 0.329 (0.095, 1.139) |
Medical status | 0.988 | 0.995 (0.505, 1.962) | 0.379 | 0.712 (0.334, 1.516) | 0.421 | 0.716 (0.317, 1.616) |
Periodontitis | 0.146 | 0.453 (0.156, 1.316) | 0.599 | 0.733 (0.231, 2.331) | 0.453 | 1.617 (0.461, 5.677) |
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Gufran, K.; Alsakr, A.M.; Alqahtani, A.S.; Alqhtani, N.R.; Alasmari, D.; Alzamil, F.F.; Alotaibi, N.M.; Alhamid, H.M.; Aldafiri, A.S. Association between Periodontitis and Chronic Rhinosinusitis Involving Maxillary Sinus Measured by Lund Mackay Staging System. Healthcare 2022, 10, 1961. https://doi.org/10.3390/healthcare10101961
Gufran K, Alsakr AM, Alqahtani AS, Alqhtani NR, Alasmari D, Alzamil FF, Alotaibi NM, Alhamid HM, Aldafiri AS. Association between Periodontitis and Chronic Rhinosinusitis Involving Maxillary Sinus Measured by Lund Mackay Staging System. Healthcare. 2022; 10(10):1961. https://doi.org/10.3390/healthcare10101961
Chicago/Turabian StyleGufran, Khalid, Abdulaziz Mohammad Alsakr, Abdullah Saad Alqahtani, Nasser Raqe Alqhtani, Dhafer Alasmari, Faisal Fahad Alzamil, Nawaf Munawir Alotaibi, Hamid Mohammed Alhamid, and Ashwag Saleem Aldafiri. 2022. "Association between Periodontitis and Chronic Rhinosinusitis Involving Maxillary Sinus Measured by Lund Mackay Staging System" Healthcare 10, no. 10: 1961. https://doi.org/10.3390/healthcare10101961