Next Article in Journal / Special Issue
Interaction between Calcium and Actin in Guard Cell and Pollen Signaling Networks
Previous Article in Journal / Special Issue
Towards the Physics of Calcium Signalling in Plants
Article Menu

Export Article

Open AccessReview
Plants 2013, 2(4), 589-614;

Calcium Signals from the Vacuole

Department of Botany, Oklahoma State University, Stillwater, OK 74078, USA
Received: 19 August 2013 / Revised: 21 September 2013 / Accepted: 26 September 2013 / Published: 14 October 2013
(This article belongs to the Special Issue Calcium Signaling in Plants)
Full-Text   |   PDF [551 KB, uploaded 14 October 2013]


The vacuole is by far the largest intracellular Ca2+ store in most plant cells. Here, the current knowledge about the molecular mechanisms of vacuolar Ca2+ release and Ca2+ uptake is summarized, and how different vacuolar Ca2+ channels and Ca2+ pumps may contribute to Ca2+ signaling in plant cells is discussed. To provide a phylogenetic perspective, the distribution of potential vacuolar Ca2+ transporters is compared for different clades of photosynthetic eukaryotes. There are several candidates for vacuolar Ca2+ channels that could elicit cytosolic [Ca2+] transients. Typical second messengers, such as InsP3 and cADPR, seem to trigger vacuolar Ca2+ release, but the molecular mechanism of this Ca2+ release still awaits elucidation. Some vacuolar Ca2+ channels have been identified on a molecular level, the voltage-dependent SV/TPC1 channel, and recently two cyclic-nucleotide-gated cation channels. However, their function in Ca2+ signaling still has to be demonstrated. Ca2+ pumps in addition to establishing long-term Ca2+ homeostasis can shape cytosolic [Ca2+] transients by limiting their amplitude and duration, and may thus affect Ca2+ signaling. View Full-Text
Keywords: vacuole; ligand-gated Ca2+ channel; SV channel; cyclic nucleotide-gated channel; Ca2+:H+ exchanger; P-type Ca2+-ATPase vacuole; ligand-gated Ca2+ channel; SV channel; cyclic nucleotide-gated channel; Ca2+:H+ exchanger; P-type Ca2+-ATPase
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Schönknecht, G. Calcium Signals from the Vacuole. Plants 2013, 2, 589-614.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Plants EISSN 2223-7747 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top