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Article

Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS

by
Indah Yulia NINGSIH
1,
Diah Intan PURWANTI
2,
Suwidji WONGSO
2,
Bambang E. W. PRAJOGO
3 and
Gunawan INDRAYANTO
3,*
1
Faculty of Pharmacy, Jember University, Jl. Kalimantan I, 68121, Jember, Indonesia
2
PT. Angler BioChemLab, Plaza Graha Family C-25, 60226, Surabaya, Indonesia
3
Faculty of Pharmacy, Airlangga University, Jl. Dharmawangsa Dalam, 60286, Surabaya, Indonesia
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2015, 83(3), 489-500; https://doi.org/10.3797/scipharm.1411-08
Submission received: 16 November 2014 / Accepted: 14 April 2015 / Published: 14 April 2015

Abstract

An ultra-performance liquid chromatography ultra-high-resolution quadrupole-time-of-flight-mass spectrometry (UPLC-UHR-QTOF-MS) metabolite profiling of Justicia gendarussa Burm. f. leaves was performed. PCA and HCA analyses were applied to observe the clustering patterns and inter-sample relationships. It seemed that the concentrations of Ca, P, and Cu in the soil could affect the metabolite profiles of Justicia gendarussa. Six significant metabolites were proposed.
Keywords: Justicia gendarussa; UPLC-UHR-QTOF-MS; PCA; HCA; Sites of cultivation; Significant metabolites Justicia gendarussa; UPLC-UHR-QTOF-MS; PCA; HCA; Sites of cultivation; Significant metabolites

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MDPI and ACS Style

NINGSIH, I.Y.; PURWANTI, D.I.; WONGSO, S.; PRAJOGO, B.E.W.; INDRAYANTO, G. Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS. Sci. Pharm. 2015, 83, 489-500. https://doi.org/10.3797/scipharm.1411-08

AMA Style

NINGSIH IY, PURWANTI DI, WONGSO S, PRAJOGO BEW, INDRAYANTO G. Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS. Scientia Pharmaceutica. 2015; 83(3):489-500. https://doi.org/10.3797/scipharm.1411-08

Chicago/Turabian Style

NINGSIH, Indah Yulia, Diah Intan PURWANTI, Suwidji WONGSO, Bambang E. W. PRAJOGO, and Gunawan INDRAYANTO. 2015. "Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS" Scientia Pharmaceutica 83, no. 3: 489-500. https://doi.org/10.3797/scipharm.1411-08

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