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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2015, 83(3), 489-500; https://doi.org/10.3797/scipharm.1411-08 (registering DOI)

Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS

1
Faculty of Pharmacy, Jember University, Jl. Kalimantan I, 68121, Jember, Indonesia
2
PT. Angler BioChemLab, Plaza Graha Family C-25, 60226, Surabaya, Indonesia
3
Faculty of Pharmacy, Airlangga University, Jl. Dharmawangsa Dalam, 60286, Surabaya, Indonesia
*
Author to whom correspondence should be addressed.
Received: 16 November 2014 / Accepted: 14 April 2015 / Published: 14 April 2015
PDF [403 KB, uploaded 8 September 2016]

Abstract

An ultra-performance liquid chromatography ultra-high-resolution quadrupole-time-of-flight-mass spectrometry (UPLC-UHR-QTOF-MS) metabolite profiling of Justicia gendarussa Burm. f. leaves was performed. PCA and HCA analyses were applied to observe the clustering patterns and inter-sample relationships. It seemed that the concentrations of Ca, P, and Cu in the soil could affect the metabolite profiles of Justicia gendarussa. Six significant metabolites were proposed.
Keywords: Justicia gendarussa; UPLC-UHR-QTOF-MS; PCA; HCA; Sites of cultivation; Significant metabolites Justicia gendarussa; UPLC-UHR-QTOF-MS; PCA; HCA; Sites of cultivation; Significant metabolites
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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MDPI and ACS Style

NINGSIH, I.Y.; PURWANTI, D.I.; WONGSO, S.; PRAJOGO, B.E.W.; INDRAYANTO, G. Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS. Sci. Pharm. 2015, 83, 489-500.

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