Diseases 2017, 5(3), 19; https://doi.org/10.3390/diseases5030019
Flavonoids and Their Metabolites: Prevention in Cardiovascular Diseases and Diabetes
Keti Zeka 1,†,*
, Ketan Ruparelia 1,†, Randolph R. J. Arroo 1
, Roberta Budriesi 2 and Matteo Micucci 2
, Roberta Budriesi 2 and Matteo Micucci 21
Leicester School of Pharmacy, Faculty of Health and Life Sciences, De Montfort University, The Gateway, Leicester LE1 9BH, UK
2
Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy
â€
These authors contributed equally to the present work.
*
Author to whom correspondence should be addressed.
Received: 2 August 2017 / Revised: 1 September 2017 / Accepted: 3 September 2017 / Published: 5 September 2017
(This article belongs to the Collection Effects of Food Antioxidants on Cardiovascular Diseases and Human Cancers)
Abstract
The occurrence of atherosclerosis and diabetes is expanding rapidly worldwide. These two metabolic disorders often co-occur, and are part of what is often referred to as the metabolic syndrome. In order to determine future therapies, we propose that molecular mechanisms should be investigated. Once the aetiology of the metabolic syndrome is clear, a nutritional intervention should be assessed. Here we focus on the protective effects of some dietary flavonoids, and their metabolites. Further studies may also pave the way for development of novel drug candidates. View Full-TextKeywords:
antioxidants; atherosclerosis; diabetes; flavonoids; metabolites
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Zeka, K.; Ruparelia, K.; Arroo, R.R.J.; Budriesi, R.; Micucci, M. Flavonoids and Their Metabolites: Prevention in Cardiovascular Diseases and Diabetes. Diseases 2017, 5, 19.
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