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Vaccines against Genital Herpes: Where Are We?

1
Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea
2
The Center for Epidemic Preparedness, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea
*
Author to whom correspondence should be addressed.
Vaccines 2020, 8(3), 420; https://doi.org/10.3390/vaccines8030420
Received: 30 June 2020 / Revised: 23 July 2020 / Accepted: 25 July 2020 / Published: 27 July 2020
(This article belongs to the Section Vaccines against Infectious Diseases)
Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development. View Full-Text
Keywords: genital herpes; vaccine; herpes simplex virus; HSV genital herpes; vaccine; herpes simplex virus; HSV
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MDPI and ACS Style

Kim, H.C.; Lee, H.K. Vaccines against Genital Herpes: Where Are We? Vaccines 2020, 8, 420. https://doi.org/10.3390/vaccines8030420

AMA Style

Kim HC, Lee HK. Vaccines against Genital Herpes: Where Are We? Vaccines. 2020; 8(3):420. https://doi.org/10.3390/vaccines8030420

Chicago/Turabian Style

Kim, Hyeon C.; Lee, Heung K. 2020. "Vaccines against Genital Herpes: Where Are We?" Vaccines 8, no. 3: 420. https://doi.org/10.3390/vaccines8030420

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