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Myoclonic Disorders

Klinik für Neurologie, Klinikum Bogenhausen, Städt. Klinikum München GmbH, Englschalkinger Str. 77, 81925 München, Germany
Author to whom correspondence should be addressed.
Academic Editors: Steven Frucht and Pichet Termsarasab
Brain Sci. 2017, 7(8), 103;
Received: 30 May 2017 / Revised: 6 August 2017 / Accepted: 8 August 2017 / Published: 14 August 2017
(This article belongs to the Special Issue Pathophysiology and Genetics of Movement Disorders)
Few movement disorders seem to make a straightforward approach to diagnosis and treatment more difficult and frustrating than myoclonus, due to its plethora of causes and its variable classifications. Nevertheless, in recent years, exciting advances have been made in the elucidation of the pathophysiology and genetic basis of many disorders presenting with myoclonus. Here, we provide a review of all of the important types of myoclonus encountered in pediatric and adult neurology, with an emphasis on the recent developments that have led to a deeper understanding of this intriguing phenomenon. An up-to-date list of the genetic basis of all major myoclonic disorders is presented. Randomized studies are scarce in myoclonus therapy, but helpful pragmatic approaches at diagnosis as well as treatment have been recently suggested. View Full-Text
Keywords: movement disorders; myoclonus; epilepsy; neurogenetics; encephalopathies movement disorders; myoclonus; epilepsy; neurogenetics; encephalopathies
MDPI and ACS Style

Eberhardt, O.; Topka, H. Myoclonic Disorders. Brain Sci. 2017, 7, 103.

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