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Article

Impact of Depression and Anxiety on Dimensions of Health-Related Quality of Life in Subjects with Parkinson’s Disease Enrolled in an Association of Patients

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Community and Family Medicine, Health Area VII—Asturias, Plaza de los Sindicatos Mineros 3, 33600 Mieres, Spain
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Health Science Research, Doctoral School, University of Valladolid, Calle Real de Burgos s/n, 47011 Valladolid, Spain
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Department of Psychology, Universidad de Oviedo, Plaza Feijoo s/n, 33003 Oviedo, Spain
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Department of Neurology, Hospital Universitario Central de Asturias (HUCA), Avenida Roma s/n, 33011 Oviedo, Spain
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Instituto de Salud del Principado de Asturias (ISPA), Avenida del Hospital Universitario s/n, 33011 Oviedo, Spain
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Department of Medicine, Universidad de Oviedo, Calle Julián Clavería 6, 33006 Oviedo, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Pablo José Olivares-Olivares
Brain Sci. 2021, 11(6), 771; https://doi.org/10.3390/brainsci11060771
Received: 3 May 2021 / Revised: 5 June 2021 / Accepted: 8 June 2021 / Published: 10 June 2021
Parkinson’s disease (PD) is a complex disorder characterized by a wide spectrum of symptoms. Depression and anxiety are common manifestations in PD and may be determinants of health-related quality of life (HRQoL). The objective of this study is to determine the association of depression and anxiety with the dimensions of HRQoL in subjects with PD enrolled in an association of patients. Ninety-five community-based patients with PD diagnosis at different disease stages were studied. HRQoL was assessed using the Parkinson’s Disease Questionnaire (PDQ-39); depression and anxiety were assessed using the Beck Depression Inventory (BDI-II) and the State-Trait Anxiety Inventory (STAI), respectively. Our results showed that depression and anxiety were negatively associated with HRQoL measured by PDSI. Higher motor dysfunction measured by Hoehn and Yahr (H&Y) staging was also associated with worse HRQoL. Depression was the most influential variable in the model. All PDQ-39 dimensions except social support and bodily discomfort were associated with depression. Anxiety was associated with the emotional well-being and bodily discomfort dimensions. These results suggest that physicians should pay attention to the presence of psychiatric symptoms and treat them appropriately. View Full-Text
Keywords: Parkinson’s disease; depression; anxiety; quality of life; nonmotor symptoms Parkinson’s disease; depression; anxiety; quality of life; nonmotor symptoms
MDPI and ACS Style

Chuquilín-Arista, F.; Álvarez-Avellón, T.; Menéndez-González, M. Impact of Depression and Anxiety on Dimensions of Health-Related Quality of Life in Subjects with Parkinson’s Disease Enrolled in an Association of Patients. Brain Sci. 2021, 11, 771. https://doi.org/10.3390/brainsci11060771

AMA Style

Chuquilín-Arista F, Álvarez-Avellón T, Menéndez-González M. Impact of Depression and Anxiety on Dimensions of Health-Related Quality of Life in Subjects with Parkinson’s Disease Enrolled in an Association of Patients. Brain Sciences. 2021; 11(6):771. https://doi.org/10.3390/brainsci11060771

Chicago/Turabian Style

Chuquilín-Arista, Fany, Tania Álvarez-Avellón, and Manuel Menéndez-González. 2021. "Impact of Depression and Anxiety on Dimensions of Health-Related Quality of Life in Subjects with Parkinson’s Disease Enrolled in an Association of Patients" Brain Sciences 11, no. 6: 771. https://doi.org/10.3390/brainsci11060771

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