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Article

Thalamus Atrophy in the Peri-Pregnancy Period in Clinically Stable Multiple Sclerosis Patients: Preliminary Results

1
Neurology Outpatient Clinic, The Holy Family Specialist Hospital, Rudna Mala, 36-060 Rzeszow, Poland
2
Medical College, University of Rzeszow, 35-310 Rzeszow, Poland
3
Pixel Technology LLC, 93-558 Lodz, Poland
4
Department of Neurology, Medical University of Lodz, 22 Kopcinskiego Str, 90-153 Lodz, Poland
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Moussa Antoine Chalah
Brain Sci. 2021, 11(10), 1270; https://doi.org/10.3390/brainsci11101270
Received: 20 June 2021 / Revised: 14 September 2021 / Accepted: 23 September 2021 / Published: 26 September 2021
(This article belongs to the Section Neurotechnology and Neuroimaging)
Radiological activity in the post-partum period in MS patients is a well-known phenomenon, but there is no data concerning the influence of pregnancy on regional brain atrophy. The aim of this article was to investigate local brain atrophy in the peri-pregnancy period (PPP) in patients with MS. Thalamic volume (TV); corpus callosum volume (CCV) and classical MRI activity (new gadolinium enhancing lesions (Gd+), new T2 lesions, T1 lesions volume (T1LV) and T2 lesions volume (T2LV)) were analyzed in 12 clinically stable women with relapsing–remitting MS and with MRI performed in the PPP. We showed that there was a significant decrease in TV (p = 0.021) in the PPP. We also observed a significant increase in the T1 lesion volume (p = 0.028), new gadolinium-enhanced and new T2 lesions (in 46% and 77% of the scans, respectively) in the post-partum period. Our results suggest that the PPP in MS may be associated not only with classical MRI activity but, also, with regional brain atrophy. View Full-Text
Keywords: pregnancy; magnetic resonance imaging; multiple sclerosis; local brain atrophy; magnetic resonance imaging activity; peri-pregnancy period pregnancy; magnetic resonance imaging; multiple sclerosis; local brain atrophy; magnetic resonance imaging activity; peri-pregnancy period
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MDPI and ACS Style

Rościszewska-Żukowska, I.; Podyma, M.; Stasiołek, M.; Siger, M. Thalamus Atrophy in the Peri-Pregnancy Period in Clinically Stable Multiple Sclerosis Patients: Preliminary Results. Brain Sci. 2021, 11, 1270. https://doi.org/10.3390/brainsci11101270

AMA Style

Rościszewska-Żukowska I, Podyma M, Stasiołek M, Siger M. Thalamus Atrophy in the Peri-Pregnancy Period in Clinically Stable Multiple Sclerosis Patients: Preliminary Results. Brain Sciences. 2021; 11(10):1270. https://doi.org/10.3390/brainsci11101270

Chicago/Turabian Style

Rościszewska-Żukowska, Iwona, Marek Podyma, Mariusz Stasiołek, and Małgorzata Siger. 2021. "Thalamus Atrophy in the Peri-Pregnancy Period in Clinically Stable Multiple Sclerosis Patients: Preliminary Results" Brain Sciences 11, no. 10: 1270. https://doi.org/10.3390/brainsci11101270

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