Clinical Evaluation of Xpert Xpress CoV-2/Flu/RSV plus and Alinity m Resp-4-Plex Assay
, Chin-Pang Leung, Candy Ling-Na Wang, Chun-Hang Au, Thomas Shek-Kong Wan, Edmond Shiu-Kwan Ma and Bone Siu-Fai Tang *
Round 1
Reviewer 1 Report
Comments and Suggestions for AuthorsI am pleasured to be invited to review the manuscript, which entitled “Clinical evaluation of Xpert Xpress CoV-2/Flu/RSV plus and 2 Alinity m Resp-4-Plex Assay”. The paper is clearly focused, well-structured, easy to read and understand, and the content and results are relevant to the topic. The development of rapid diagnostic tools indeed provides significant benefits to clinical care for patients.
Comments on the Quality of English LanguageN/A.
Reviewer 2 Report
Comments and Suggestions for AuthorsThe study aimed to evaluate the performance of Xpert Xpress CoV-2/Flu/RSV plus and Alinity m Resp-4-Plex Assay, two commercial in vitro diagnostic NAATs for the qualitative detection of SARS-CoV-2, influenza A and B viruses, and respiratory syncytial virus (RSV). The respiratory specimens included were from upper and lower respiratory tract, which are routinely tested with any of or combination of SOC methods. The performance of both assays was comparable to the SOC methods. Two versions of the paper are available. The second one has a lot of improvement, specially in the introduction and discussion. The manuscript is clear, relevant for the field and presented in a well-structured manner, therefore I highly recommend its publication.
