Morphological Change in Optical Coherence Tomography and Functional Outcomes in Epiretinal Membrane Peeling with or without SF6 Tamponade
Abstract
:1. Introduction
2. Materials and Methods
2.1. Surgical Techniques
2.2. Outcome Measurements
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Total (N = 89) | BSS (N = 34) | SF6 (N = 55) | p Value | |
---|---|---|---|---|
Age (years) | 65.79 ± 7.47 | 64.44 ± 9.11 | 66.62 ± 6.09 | 0.209 a |
Gender | 0.176 b | |||
Male | 34 (38%) | 16 (47%) | 18 (33%) | |
Female | 55 (62%) | 18 (53%) | 37 (67%) | |
Comorbidities | ||||
Hypertension | 42 (47%) | 19 (56%) | 23 (42%) | |
Diabetes mellitus | 15 (17%) | 8 (24%) | 7 (13%) | |
Hyperlipidemia | 15 (17%) | 3 (9%) | 12 (22%) | |
Thyroid disease | 7 (8%) | 3 (9%) | 4 (7%) | |
Status post retinal laser | 6 (7%) | 4 (12%) | 1 (2%) | |
ESRD on hemodialysis | 4 (4%) | 3 (9%) | 1 (2%) | |
Laterality | 0.676 b | |||
OD | 47 (53%) | 17 (50%) | 30 (55%) | |
OS | 42 (47%) | 17 (50%) | 25 (45%) | |
Lens status | 0.072 c | |||
Phakic | 76 (85%) | 26 (76%) | 50 (91%) | |
Pseudophakic | 13 (25%) | 8 (24%) | 5 (9%) | |
Axial length (mm) | 24.68 ± 1.95 | 24.83 ± 1.80 | 24.59 ± 2.03 | 0.219 a |
Follow-up duration (months) | 18.20 ± 8.57 | 17.62 ± 8.59 | 18.56 ± 8.54 | 0.603 a |
Baseline IOP (mmHg) | 15.25 ± 3.29 | 14.92 ± 3.12 | 15.45 ± 3.37 | 0.438 a |
Baseline BCVA (logMAR) | 0.68 ± 0.36 | 0.53 ± 0.28 | 0.78 ± 0.37 | 0.004 a* |
Baseline CMT (µm) | 465.46 ± 103.10 | 460 ± 100.55 | 468.65 ± 104.53 | 0.497 a |
CMT (µm) | BCVA (logMAR) | |||||
---|---|---|---|---|---|---|
BSS (N = 34) | SF6 (N = 55) | p Value | BSS (N = 34) | SF6 (N = 55) | p Value | |
Baseline | 460 ± 100.55 | 468.65 ± 104.53 | 0.497 a | 0.53 ± 0.28 | 0.78 ± 0.37 | 0.004 a* |
Postoperative 1 month | 400.82 ± 69.72 | 407.91 ± 66.57 | 0.639 a | 0.43 ± 0.26 | 0.71 ± 0.49 | 0.012 a* |
Postoperative 3 months | 376.94 ± 61.91 | 390.40 ± 54.58 | 0.328 a | 0.43 ± 0.35 | 0.61 ± 0.41 | 0.055 a |
Postoperative 6 months | 367.18 ± 59.61 | 375.63 ± 52.07 | 0.461 a | 0.48 ± 0.47 | 0.51 ± 0.42 | 0.511 a |
Last follow-up | 365.73 ± 57.17 | 373.51 ± 63.13 | 0.924 a | 0.21 ± 0.26 | 0.46 ± 0.47 | 0.003 a* |
p value | <0.001 b* | <0.001 b* | <0.001 b* | <0.001 b* |
IOP | Baseline | Postoperative 1 Week | Postoperative 1 Month |
---|---|---|---|
BSS (N = 34) | 14.92 ± 3.12 | 13.90 ± 4.17 | 15.28 ± 4.96 |
SF6 (N = 55) | 15.45 ± 3.37 | 15.64 ± 5.55 | 14.36 ± 3.94 |
p value | 0.438 a | 0.196 a | 0.387 a |
Univariate Analyses | Multivariate Analyses | |||
---|---|---|---|---|
Odds Ratio (95% CI) | p Value | Odds Ratio (95% CI) | p Value | |
Age | 1.143 (1.062–1.231) | <0.001 * | 1.187 (0.991–1.422) | 0.063 |
Gender (Reference: female) | 1.085 (0.461–2.554) | 0.852 | 0.593 (0.066–5.293) | 0.640 |
PPVT alone or combined cataract surgery (Reference: PPVT alone) | 0.452 (0.175–1.165) | 0.100 | 7.829 (0.423–144.795) | 0.167 |
Axial length | 0.619 (0.434–0.883) | 0.008 * | 0.152 (0.039–0.600) | 0.007 * |
BSS or SF6 (Reference: SF6) | 0.176 (0.067–0.461) | <0.001 * | 0.139 (0.017–1.145) | 0.067 |
Preoperative BCVA (logMAR) | 15.625 (3.387–72.086) | <0.001 * | 192.342 (2.316–15,971.393) | 0.020 * |
Preoperative CMT | 1.001 (0.997–1.005) | 0.619 | 1.006 (0.989–1.022) | 0.498 |
Last CMT | 1.002 (0.995–1.010) | 0.513 | 0.990 (0.964–1.017) | 0.450 |
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Chi, Y.-C.; Chu, W.-L.; Chen, K.-J.; Cheng, K.-C. Morphological Change in Optical Coherence Tomography and Functional Outcomes in Epiretinal Membrane Peeling with or without SF6 Tamponade. Diagnostics 2024, 14, 1483. https://doi.org/10.3390/diagnostics14141483
Chi Y-C, Chu W-L, Chen K-J, Cheng K-C. Morphological Change in Optical Coherence Tomography and Functional Outcomes in Epiretinal Membrane Peeling with or without SF6 Tamponade. Diagnostics. 2024; 14(14):1483. https://doi.org/10.3390/diagnostics14141483
Chicago/Turabian StyleChi, Yi-Chun, Wei-Lun Chu, Kuo-Jen Chen, and Kai-Chun Cheng. 2024. "Morphological Change in Optical Coherence Tomography and Functional Outcomes in Epiretinal Membrane Peeling with or without SF6 Tamponade" Diagnostics 14, no. 14: 1483. https://doi.org/10.3390/diagnostics14141483
APA StyleChi, Y.-C., Chu, W.-L., Chen, K.-J., & Cheng, K.-C. (2024). Morphological Change in Optical Coherence Tomography and Functional Outcomes in Epiretinal Membrane Peeling with or without SF6 Tamponade. Diagnostics, 14(14), 1483. https://doi.org/10.3390/diagnostics14141483