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A Model of Evolution of Development Based on Germline Penetration of New “No-Junk” DNA

Factors Behind Junk DNA in Bacteria

by 1,* and 1,2
Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, Apartado Postal 22085, 46071 València, Spain
Genómica y Salud, Centro Superior de Investigación en Salud Pública (CSISP), Avenida de Cataluña 21, 46020 Valencia, Spain
Author to whom correspondence should be addressed.
Genes 2012, 3(4), 634-650;
Received: 25 July 2012 / Revised: 11 September 2012 / Accepted: 25 September 2012 / Published: 12 October 2012
(This article belongs to the Special Issue Junk DNA' is not Junk)
Although bacterial genomes have been traditionally viewed as being very compact, with relatively low amounts of repetitive and non-coding DNA, this view has dramatically changed in recent years. The increase of available complete bacterial genomes has revealed that many species present abundant repetitive DNA (i.e., insertion sequences, prophages or paralogous genes) and that many of these sequences are not functional but can have evolutionary consequences as concerns the adaptation to specialized host-related ecological niches. Comparative genomics analyses with close relatives that live in non-specialized environments reveal the nature and fate of this bacterial junk DNA. In addition, the number of insertion sequences and pseudogenes, as well as the size of the intergenic regions, can be used as markers of the evolutionary stage of a genome. View Full-Text
Keywords: junk DNA; pseudogenes; intergenic regions (IGR); insertion sequences (IS); genome degradation junk DNA; pseudogenes; intergenic regions (IGR); insertion sequences (IS); genome degradation
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MDPI and ACS Style

Gil, R.; Latorre, A. Factors Behind Junk DNA in Bacteria. Genes 2012, 3, 634-650.

AMA Style

Gil R, Latorre A. Factors Behind Junk DNA in Bacteria. Genes. 2012; 3(4):634-650.

Chicago/Turabian Style

Gil, Rosario, and Amparo Latorre. 2012. "Factors Behind Junk DNA in Bacteria" Genes 3, no. 4: 634-650.

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