Next Article in Journal
pH-Induced Association and Dissociation of Intermolecular Complexes Formed by Hydrogen Bonding between Diblock Copolymers
Next Article in Special Issue
Recent Advances in Antimicrobial Hydrogels Containing Metal Ions and Metals/Metal Oxide Nanoparticles
Previous Article in Journal
Aromatic Modification of Low Molecular Weight PEI for Enhanced Gene Delivery
Previous Article in Special Issue
Fabrication of Highly Crosslinked Gelatin Hydrogel and Its Influence on Chondrocyte Proliferation and Phenotype
Open AccessFeature PaperReview

Hydrogel Based Sensors for Biomedical Applications: An Updated Review

by 1,* and 2,*
1
Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide 5042, SA, Australia
2
Institute for Nano Scale Science & Technology, College of Science and Engineering, Flinders University, Adelaide 5042, SA, Australia
*
Authors to whom correspondence should be addressed.
Polymers 2017, 9(8), 364; https://doi.org/10.3390/polym9080364
Received: 20 July 2017 / Revised: 10 August 2017 / Accepted: 12 August 2017 / Published: 16 August 2017
(This article belongs to the Special Issue Hydrogels in Tissue Engineering and Regenerative Medicine)
Biosensors that detect and convert biological reactions to a measurable signal have gained much attention in recent years. Between 1950 and 2017, more than 150,000 papers have been published addressing the applications of biosensors in different industries, but to the best of our knowledge and through careful screening, critical reviews that describe hydrogel based biosensors for biomedical applications are rare. This review discusses the biomedical application of hydrogel based biosensors, based on a search performed through Web of Science Core, PubMed (NLM), and Science Direct online databases for the years 2000–2017. In this review, we consider bioreceptors to be immobilized on hydrogel based biosensors, their advantages and disadvantages, and immobilization techniques. We identify the hydrogels that are most favored for this type of biosensor, as well as the predominant transduction strategies. We explain biomedical applications of hydrogel based biosensors including cell metabolite and pathogen detection, tissue engineering, wound healing, and cancer monitoring, and strategies for small biomolecules such as glucose, lactate, urea, and cholesterol detection are identified. View Full-Text
Keywords: hydrogel based biosensor; hydrogel; bioreceptors; immobilization; biomedical application; transduction strategies hydrogel based biosensor; hydrogel; bioreceptors; immobilization; biomedical application; transduction strategies
Show Figures

Graphical abstract

MDPI and ACS Style

Tavakoli, J.; Tang, Y. Hydrogel Based Sensors for Biomedical Applications: An Updated Review. Polymers 2017, 9, 364. https://doi.org/10.3390/polym9080364

AMA Style

Tavakoli J, Tang Y. Hydrogel Based Sensors for Biomedical Applications: An Updated Review. Polymers. 2017; 9(8):364. https://doi.org/10.3390/polym9080364

Chicago/Turabian Style

Tavakoli, Javad; Tang, Youhong. 2017. "Hydrogel Based Sensors for Biomedical Applications: An Updated Review" Polymers 9, no. 8: 364. https://doi.org/10.3390/polym9080364

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop