Next Article in Journal
Supramolecular Functionalities Influence the Thermal Properties, Interactions and Conductivity Behavior of Poly(ethylene glycol)/LiAsF6 Blends
Previous Article in Journal
Extensional Flow Properties of Externally Plasticized Cellulose Acetate: Influence of Plasticizer Content
Previous Article in Special Issue
Challenges in Multiscale Modeling of Polymer Dynamics
Article

Coarse-Grained Models for Protein-Cell Membrane Interactions

1
Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia,PA 19104, USA
2
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA
*
Author to whom correspondence should be addressed.
Polymers 2013, 5(3), 890-936; https://doi.org/10.3390/polym5030890
Received: 26 April 2013 / Revised: 20 June 2013 / Accepted: 20 June 2013 / Published: 2 July 2013
(This article belongs to the Special Issue Multiscale Simulations in Soft Matter)
The physiological properties of biological soft matter are the product of collective interactions, which span many time and length scales. Recent computational modeling efforts have helped illuminate experiments that characterize the ways in which proteins modulate membrane physics. Linking these models across time and length scales in a multiscale model explains how atomistic information propagates to larger scales. This paper reviews continuum modeling and coarse-grained molecular dynamics methods, which connect atomistic simulations and single-molecule experiments with the observed microscopic or mesoscale properties of soft-matter systems essential to our understanding of cells, particularly those involved in sculpting and remodeling cell membranes. View Full-Text
Keywords: molecular dynamics; coarse-grained model; membrane proteins molecular dynamics; coarse-grained model; membrane proteins
Show Figures

Figure 1

MDPI and ACS Style

Bradley, R.; Radhakrishnan, R. Coarse-Grained Models for Protein-Cell Membrane Interactions. Polymers 2013, 5, 890-936. https://doi.org/10.3390/polym5030890

AMA Style

Bradley R, Radhakrishnan R. Coarse-Grained Models for Protein-Cell Membrane Interactions. Polymers. 2013; 5(3):890-936. https://doi.org/10.3390/polym5030890

Chicago/Turabian Style

Bradley, Ryan, and Ravi Radhakrishnan. 2013. "Coarse-Grained Models for Protein-Cell Membrane Interactions" Polymers 5, no. 3: 890-936. https://doi.org/10.3390/polym5030890

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop