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Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

1
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, India
2
Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Abo Akademi University, 20520 Turku, Finland
*
Author to whom correspondence should be addressed.
Pharmaceutics 2018, 10(4), 191; https://doi.org/10.3390/pharmaceutics10040191
Received: 14 July 2018 / Revised: 23 September 2018 / Accepted: 26 September 2018 / Published: 18 October 2018
(This article belongs to the Special Issue Functional Nanohybrids for Drug Delivery)
Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications. View Full-Text
Keywords: solid lipid nanoparticles; cytotoxicity; targeted drug delivery; colloidal nanocarriers solid lipid nanoparticles; cytotoxicity; targeted drug delivery; colloidal nanocarriers
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MDPI and ACS Style

Mishra, V.; Bansal, K.K.; Verma, A.; Yadav, N.; Thakur, S.; Sudhakar, K.; Rosenholm, J.M. Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems. Pharmaceutics 2018, 10, 191.

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