Performance Evaluation of the VIDAS® Measles IgG Assay and Its Diagnostic Value for Measuring IgG Antibody Avidity in Measles Virus Infection
Abstract
:1. Introduction
2. Material and Methods
2.1. Presentation of the Kits Used in This Study
2.2. Selection of the Sera
2.3. International Standard
2.4. Statistical Analysis
3. Results
3.1. Population Characteristics
3.2. Relative Performance of the VIDAS® Assay
3.3. Detection Threshold
3.4. Avidity Index for Anti-Measles Virus IgG
4. Discussion
5. Conclusion
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Enzygnost® Measles IgG | Total | ||||
---|---|---|---|---|---|
Negatives | Equivocal | Positives | |||
VIDAS® Measles IgG | Negatives | 5 | 2 | 0 | 7 |
Equivocal | 2 | 3 | 0 | 5 | |
Positives | 0 | 5 | 304 | 309 | |
Total | 7 | 10 | 304 | 321 |
Measles IgG Capture EIA® Microimmune | Total | ||||
---|---|---|---|---|---|
Negatives | Equivocal | Positives | |||
VIDAS® Measles IgG | Negatives | 6 | 0 | 1 | 7 |
Equivocal | 1 | 2 | 2 | 5 | |
Positives | 0 | 1 | 308 | 309 | |
Total | 7 | 3 | 311 | 321 |
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Dina, J.; Creveuil, C.; Gouarin, S.; Viron, F.; Hebert, A.; Freymuth, F.; Vabret, A. Performance Evaluation of the VIDAS® Measles IgG Assay and Its Diagnostic Value for Measuring IgG Antibody Avidity in Measles Virus Infection. Viruses 2016, 8, 234. https://doi.org/10.3390/v8080234
Dina J, Creveuil C, Gouarin S, Viron F, Hebert A, Freymuth F, Vabret A. Performance Evaluation of the VIDAS® Measles IgG Assay and Its Diagnostic Value for Measuring IgG Antibody Avidity in Measles Virus Infection. Viruses. 2016; 8(8):234. https://doi.org/10.3390/v8080234
Chicago/Turabian StyleDina, Julia, Christian Creveuil, Stephanie Gouarin, Florent Viron, Amelie Hebert, Francois Freymuth, and Astrid Vabret. 2016. "Performance Evaluation of the VIDAS® Measles IgG Assay and Its Diagnostic Value for Measuring IgG Antibody Avidity in Measles Virus Infection" Viruses 8, no. 8: 234. https://doi.org/10.3390/v8080234
APA StyleDina, J., Creveuil, C., Gouarin, S., Viron, F., Hebert, A., Freymuth, F., & Vabret, A. (2016). Performance Evaluation of the VIDAS® Measles IgG Assay and Its Diagnostic Value for Measuring IgG Antibody Avidity in Measles Virus Infection. Viruses, 8(8), 234. https://doi.org/10.3390/v8080234