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Modulation of Apoptotic Pathways by Human Papillomaviruses (HPV): Mechanisms and Implications for Therapy
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The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature

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University of California, 653 E. Peltason Road Suite 2024, Irvine 92697, CA, USA
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Epicentro, Jr. Jaén 250 A, 4, Lima, Peru
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Universidad Nacional Mayor de San Marcos Instituto de Medicina Tropical, Av. Germán Amézaga s/n. Ciudad Universitaria, 1, Lima, Peru
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UCLA Program in Global Health, 9911 West Pico Blvd., Suite 955, Los Angeles 90035, CA, USA
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Author to whom correspondence should be addressed.
Viruses 2012, 4(12), 3851-3858; https://doi.org/10.3390/v4123851
Received: 22 November 2012 / Revised: 14 December 2012 / Accepted: 17 December 2012 / Published: 18 December 2012
Human Papillomavirus (HPV) infection is the most common sexually transmitted infection (STI) worldwide. Incidence rates of HPV infection among human immunodeficiency virus (HIV)-infected individuals are well documented and are several-fold higher than among HIV-uninfected individuals. Few studies have demonstrated an increased risk for acquiring HIV infection in those with HPV infection, and this risk seems to be higher when HPV strains are of high-risk oncogenic potential. The estimated prevalence of high-risk oncogenic HPV infection is highest in men who have sex with men (MSM), a particularly vulnerable group with high prevalence rates of HIV infection and other STIs. In this paper, we provide a comprehensive review of the available literature on the role of HPV infection in HIV acquisition. Our review includes data from cross-sectional and longitudinal studies. View Full-Text
Keywords: human papillomavirus; human immunodeficiency virus; men who have sex with men; HIV incidence; review; HPV testing human papillomavirus; human immunodeficiency virus; men who have sex with men; HIV incidence; review; HPV testing
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Brown, B.; Davtyan, M.; Galea, J.; Chow, E.; Leon, S.; Klausner, J.D. The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature. Viruses 2012, 4, 3851-3858.

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