Next Article in Journal
A VSV-G Pseudotyped Last Generation Lentiviral Vector Mediates High Level and Persistent Gene Transfer in Models of Airway Epithelium In Vitro and In Vivo
Previous Article in Journal
Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
Article Menu

Export Article

Open AccessCommentary

Multitasking: Making the Most out of the Retroviral Envelope

Department of Veterinary Medicine, University of Cambridge, Madingley Road, CB3 0ES, Cambridge, England, UK
Medical Research Council - University of Glasgow Centre for Virus Research, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Scotland, UK
Author to whom correspondence should be addressed.
Viruses 2010, 2(8), 1571-1576;
Received: 16 June 2010 / Revised: 26 July 2010 / Accepted: 26 July 2010 / Published: 2 August 2010
(This article belongs to the Section Editorial)
PDF [80 KB, uploaded 12 May 2015]


Evasion of the host’s immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain "encrypted" within their envelope glycoprotein that is required to establish a successful infection in immunocompetent hosts [1]. View Full-Text
Keywords: retroviruses; immune suppression; envelope retroviruses; immune suppression; envelope

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Varela, M.; Palmarini, M. Multitasking: Making the Most out of the Retroviral Envelope. Viruses 2010, 2, 1571-1576.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top