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Hematology Reviews
Volume 1
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10.4081/hr.2009.e8
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Hematology Reviews (renamed as Hematology Reports here since 2010) is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

MicroRNAs: Tiny Players with a Big Role in the Pathogenesis of Leukemias and Lymphomas

by
Francesca Fanini
1,
Ivan Vannini
1 and
Muller Fabbri
1,2,*
1
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, 47014 Meldola, Italy
2
Department of Molecular Virology, Immunology, and Medical Genetics and Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA
*
Author to whom correspondence should be addressed.
Hematol. Rev. 2009, 1(1), e8; https://doi.org/10.4081/hr.2009.e8 (registering DOI)
Submission received: 29 April 2009 / Revised: 1 May 2009 / Accepted: 5 May 2009 / Published: 14 May 2009

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) with important regulatory functions. After an initial phase, aimed at identifying whether a deregulation in miRNA expression occurred between hematologic malignancies and their normal counterparts, currently an increasing number of studies are focusing on the functional significance of these aberrancies. The identification of miRNA targeted genes has cast a new light on the role of these tiny ncRNAs in human cancerogenesis, providing a new rationale to the observed diagnostic, prognostic and therapeutic implications of miRNA aberrant expression in human hematologic malignancies.

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MDPI and ACS Style

Fanini, F.; Vannini, I.; Fabbri, M. MicroRNAs: Tiny Players with a Big Role in the Pathogenesis of Leukemias and Lymphomas. Hematol. Rev. 2009, 1, e8. https://doi.org/10.4081/hr.2009.e8

AMA Style

Fanini F, Vannini I, Fabbri M. MicroRNAs: Tiny Players with a Big Role in the Pathogenesis of Leukemias and Lymphomas. Hematology Reviews. 2009; 1(1):e8. https://doi.org/10.4081/hr.2009.e8

Chicago/Turabian Style

Fanini, Francesca, Ivan Vannini, and Muller Fabbri. 2009. "MicroRNAs: Tiny Players with a Big Role in the Pathogenesis of Leukemias and Lymphomas" Hematology Reviews 1, no. 1: e8. https://doi.org/10.4081/hr.2009.e8

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