Effects of Augmented Reality Game-Based Cognitive–Motor Training on Restricted and Repetitive Behaviors and Executive Function in Patients with Autism Spectrum Disorder
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Ethics Statement and Trial Registration
2.3. Study Participants
2.4. Randomization and Blinding
2.5. Experiment Procedures
2.5.1. Study Group
2.5.2. Control Group
2.6. Outcome Measurements
2.6.1. RRBs
2.6.2. EF and Reaction Time
2.7. Data Analysis
3. Results
3.1. RRBs
3.2. EF and Reaction Time
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variables | Study Group (n = 12) | Control Group (n = 12) | p |
---|---|---|---|
Male/Female (%) | 10/2 (83/17) | 12/0 (100/0) | - |
Age (years) | 14.42 ± 5.14 | 14.17 ± 5.09 | 0.977 |
Height (cm) | 155.42 ± 11.64 | 153.42 ± 11.75 | 0.525 |
Weight (kg) | 53.42 ± 9.52 | 53.33 ± 11.33 | 0.840 |
AMSE (points) | 3.33 ± 1.30 | 3.58 ± 1.31 | 0.651 |
Variables | Study Group (n = 12) | Control Group (n = 12) | Mixed 2 × 2 ANOVA | ||||
---|---|---|---|---|---|---|---|
Pre-Test | Post-Test | Pre-Test | Post-Test | p | Time F-Value | Time × Group F-Value | |
Stereotypic behavior (points) | 5.50 ± 1.00 | 4.75 ± 1.05 * | 5.92 ± 1.24 | 5.50 ± 1.67 | 0.215 | 11.846 ** | 0.967 |
Self-injury behavior (points) | 1.75 ± 0.75 | 1.25 ± 0.86 | 1.83 ± 0.83 | 1.33 ± 1.07 | 0.778 | 7.333 * | 0.000 *** |
Compulsive behavior (points) | 3.50 ± 1.00 | 2.83 ± 1.33 * | 4.00 ± 1.34 | 3.42 ± 1.50 * | 0.749 | 15.184 ** | 0.067 |
Ritualistic behavior (points) | 7.00 ± 1.12 | 6.33 ± 1.72 | 6.83 ± 1.11 | 6.25 ± 1.48 | 0.833 | 8.756 ** | 0.039 * |
Sameness behavior (points) | 8.50 ± 0.90 | 7.67 ± 1.15 * | 8.92 ± 1.37 | 8.58 ± 1.73 | 0.289 | 8.045 * | 1.478 |
Restricted behavior (points) | 3.50 ± 0.90 | 2.50 ± 1.44 * | 3.75 ± 1.21 | 3.08 ± 1.50 * | 0.426 | 13.750 ** | 0.550 |
Variables | Study Group (n = 12) | Control Group (n = 12) | Mixed 2 × 2 ANOVA | |||||
---|---|---|---|---|---|---|---|---|
Pre-Test | Post-Test | Pre-Test | Post-Test | p | Time F-Value | Time × Group F-Value | ||
Working memory (points) | 13.92 ± 1.50 | 13.92 ± 1.50 * | 14.08 ± 1.83 | 15.17 ± 1.19* | 0.977 | 11.407 ** | 0.016 | |
Cognitive Flexibility | RT (milliseconds) | 1102.08 ± 5.46 | 1092.25 ± 5.15 ** | 1102.00 ± 5.20 | 1098.58 ± 5.12* | 0.016 | 30.630 *** | 7.184 * |
AR (points) | 79.08 ± 3.02 | 84.83 ± 2.40 ** | 79.25 ± 4.11 | 81.92 ± 2.42 * | 0.043 | 12.950 ** | 6.349 * | |
Cognitive Inhibition | RT (milliseconds) | 1104.92 ± 8.17 | 1102.17 ± 7.34 * | 1104.83 ± 5.13 | 1104.25 ± 5.17 | 0.045 | 12.308 ** | 5.200 * |
AR (points) | 76.08 ± 2.06 | 84.33 ± 2.10 ** | 76.33 ± 3.79 | 81.08 ± 2.42 * | 0.042 | 14.503 ** | 4.351 * |
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Nekar, D.M.; Lee, D.-Y.; Hong, J.-H.; Kim, J.-S.; Kim, S.-G.; Seo, Y.-G.; Yu, J.-H. Effects of Augmented Reality Game-Based Cognitive–Motor Training on Restricted and Repetitive Behaviors and Executive Function in Patients with Autism Spectrum Disorder. Healthcare 2022, 10, 1981. https://doi.org/10.3390/healthcare10101981
Nekar DM, Lee D-Y, Hong J-H, Kim J-S, Kim S-G, Seo Y-G, Yu J-H. Effects of Augmented Reality Game-Based Cognitive–Motor Training on Restricted and Repetitive Behaviors and Executive Function in Patients with Autism Spectrum Disorder. Healthcare. 2022; 10(10):1981. https://doi.org/10.3390/healthcare10101981
Chicago/Turabian StyleNekar, Daekook M., Dong-Yeop Lee, Ji-Heon Hong, Jin-Seop Kim, Seong-Gil Kim, Yong-Gon Seo, and Jae-Ho Yu. 2022. "Effects of Augmented Reality Game-Based Cognitive–Motor Training on Restricted and Repetitive Behaviors and Executive Function in Patients with Autism Spectrum Disorder" Healthcare 10, no. 10: 1981. https://doi.org/10.3390/healthcare10101981