Next Article in Journal
Climate Change and Vector-borne Diseases: An Economic Impact Analysis of Malaria in Africa
Previous Article in Journal
Life-long Programming Implications of Exposure to Tobacco Smoking and Nicotine Before and Soon After Birth: Evidence for Altered Lung Development
Open AccessArticle

Clinical, Radiological, and Pathological Investigation of Asbestosis

1
Asbestos Research Center, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku Okayama City, 702-8055, Japan
2
Department of Radiology, Okayama University School of Medicine, 2-5-1,Shikata-cho, Kitaku, Okayama City, 702-8558, Japan
3
Department of Radiology, Dokkyo Medical University, 880, Kitakobayashi, Mibumati, Shimotuga-gun, Tochigi City, 321-0293, Japan
4
Department of Radiology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki City, 852-8501, Japan
5
Department of Pathology, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minamiku, Hiroshima City, 734-0037, Japan
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2011, 8(3), 899-912; https://doi.org/10.3390/ijerph8030899
Received: 24 February 2011 / Revised: 18 March 2011 / Accepted: 20 March 2011 / Published: 22 March 2011
By the radiological examination, differential diagnosis of asbestosis from chronic interstitial pneumonia such as IPF/UIP is difficult. The pathological features of asbestosis show the peribronchiolar fibrosis which suggest that asbestos fibers cause the inflammation of bronchioli. Therefore, the criteria for pathological diagnosis of asbestosis in 2010, contain the finding of peribronchiolar fibrosis again. Chest CT scanning including HRCT for total of 38 cases clinically diagnosed asbestosis were reviewed by 3 radiologists and one pulmonologist. On the other hand, the histology of lung tissues obtained by surgery or autopsy were examined by 4 pulmonological pathologists. Furthermore, the content of asbestos bodies in the lung was counted by phase-contrast microscopy. Thirteen cases were definitely diagnosed of asbestosis in the image including HRCT and 17 cases were diagnosed by the histopathological examination showing lung fibrosis with peribronchiolar fibrosis. Only 10 cases were indicated asbestosis by both the radiological and histopathological examinations. The mean value of asbestos bodies for these cases, was 2,133,255 per gram of dry lung tissue. View Full-Text
Keywords: asbestosis; peribronchiolar fibrosis; IPF/UIF; asbestos body asbestosis; peribronchiolar fibrosis; IPF/UIF; asbestos body
MDPI and ACS Style

Kishimoto, T.; Kato, K.; Arakawa, H.; Ashizawa, K.; Inai, K.; Takeshima, Y. Clinical, Radiological, and Pathological Investigation of Asbestosis. Int. J. Environ. Res. Public Health 2011, 8, 899-912.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop