Next Article in Journal
The Impact of the 2002 Delaware Smoking Ordinance on Heart Attack and Asthma
Next Article in Special Issue
The Impact of Nutritional Status and Longitudinal Recovery of Motor and Cognitive Milestones in Internationally Adopted Children
Previous Article in Journal
Pathophysiological Impact of Cigarette Smoke Exposure on the Cerebrovascular System with a Focus on the Blood-brain Barrier: Expanding the Awareness of Smoking Toxicity in an Underappreciated Area
Open AccessArticle

Dyslipidaemia and Undernutrition in Children from Impoverished Areas of Maceió, State of Alagoas, Brazil

1
Faculdade de Nutrição, Universidade Federal de Alagoas, Av. Lorival Melo Mota, Tabuleiro do Martins, 57072-970, Maceió, AL, Brazil
2
Departamento de Fisiologia da Nutrição, Universidade Federal de São Paulo, Rua Botucatu 862, Vila Clementino, 04023-060, São Paulo, SP, Brazil
3
Faculdade de Medicina, Universidade Federal de Alagoas, Campus A.C. Simoes, Tabuleiro do Martins, 57072-970, Maceió, AL, Brazil
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2010, 7(12), 4139-4151; https://doi.org/10.3390/ijerph7124139
Received: 11 October 2010 / Revised: 23 November 2010 / Accepted: 24 November 2010 / Published: 30 November 2010
(This article belongs to the Special Issue Malnutrition and Public Health)
Chronic undernutrition causes reduced growth and endocrine adaptations in order to maintain basic life processes. In the present study, the biochemical profiles of chronically undernourished children were determined in order to test the hypothesis that chronic undernutrition also causes changes in lipid profile in pre-school children. The study population comprised 80 children aged between 12 and 71 months, including 60 with moderate undernutrition [height-for-age Z (HAZ) scores ≤ −2 and > −3] and 20 with severe undernutrition (HAZ scores ≤ −3). Socioeconomic, demographic and environmental data were obtained by application of a questionnaire, and anthropometric measurements and information relating to sex, age and feeding habits were collected by a trained nutritionist. Blood samples were analysed for haemoglobin, vitamin A, insulin-like growth factor 1 (IGF-1) and serum lipids, while cortisol was assayed in the saliva. Faecal samples were submitted to parasitological investigation. Analysis of variance and χ2 methods were employed in order to select the variables that participated in the multivariate logistic regression analysis. The study population was socioeconomically homogeneous, while the lack of a treated water supply was clearly associated with the degree of malnutrition. Most children were parasitised and anaemia was significantly more prevalent among the severely undernourished. Levels of IGF-1 decreased significantly with increasing severity of undernutrition. Lipid analysis revealed that almost all of the children had dyslipidemia, while low levels of high-density lipoprotein were associated with the degree of undernutrition. It is concluded that chronic malnutrition causes endocrine changes that give rise to alterations in the metabolic profile of pre-school children. View Full-Text
Keywords: childhood undernutrition; metabolic disorders; dyslipidemia; anaemia; parasitosis; insulin-like growth factor 1; cortisol; multivariate logistic regression analysis childhood undernutrition; metabolic disorders; dyslipidemia; anaemia; parasitosis; insulin-like growth factor 1; cortisol; multivariate logistic regression analysis
MDPI and ACS Style

Veiga, G.R.S.; Ferreira, H.S.; Sawaya, A.L.; Calado, J.; Florêncio, T.M.M.T. Dyslipidaemia and Undernutrition in Children from Impoverished Areas of Maceió, State of Alagoas, Brazil. Int. J. Environ. Res. Public Health 2010, 7, 4139-4151.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop