Serum Ghrelin Levels in Saudi Obese Asthmatic School-Children—Correlation with Interleukin-4, Interleukin-5, and Interleukin-21
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Setting
2.2. Biochemical Evaluation
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Variable | Number | Median | Mean | SD |
---|---|---|---|---|
Non-obese non-asthmatic | 101 | 166 | 174.02 | 31.23 |
Non-obese asthmatic | 100 | 212 | 199.25 | 27.13 |
Obese non-asthmatic | 100 | 190 | 186.21 | 30.99 |
Obese asthmatic | 100 | 210 | 197.43 | 27.09 |
Parameter (Median, Mean ± SD) | Asthmatics: N (200) | Non-Asthmatics: N (201) | p Value |
---|---|---|---|
Ghrelin, ng/mL | 210, 198.40 ± 27.06 | 178, 180.10 ± 31.63 | 0.001 * |
IL-4, pg/mL | 172.5, 191.02 ± 45.98 | 163, 175.51 ± 38.52 | 0.001 * |
IL-5, pg/mL | 35, 36.51 ± 6.14 | 34, 35.08 ± 3.58 | 0.124 |
IL-21, µg/mL | 880, 896.20 ± 157.66 | 824, 843.45 ± 119.16 | 0.003 * |
Parameter (Mean ±SD) | Controlled: N (120) | Uncontrolled: N (80) | p Value |
---|---|---|---|
Ghrelin, ng/mL | 193.81 ± 27.51 | 204.95 ± 25.12 | 0.002 * |
IL-4, pg/mL | 190.00 ± 48.45 | 191.10 ± 44.46 | 0.214 |
IL-5, pg/mL | 35.51 ± 5.47 | 38.02 ± 6.77 | 0.001 * |
IL-21, µg/mL | 857.51 ± 133.10 | 954.25 ± 173.70 | 0.001 * |
Variables | aOR | 95% CI | p Value |
---|---|---|---|
Sex: males vs. females | 0.449 | 0.179–1.129 | 0.089 |
Obesity: obese vs. non-obese | 1.057 | 0.669–1.669 | 0.812 |
Asthmatic: Asthmatics vs. non-asthmatics * | 2.191 | 1.344–3.571 | 0.002 |
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Al-Ayed, M.S.; Al-Shaibari, K.S.; Alshehri, D.; Alzahrani, M.J.; Nasser, I.; Alaamri, H.S.; Alaseeri, W.A.; Mahfouz, A.A.; Alsareii, S.A.; Asaad, A.M.; et al. Serum Ghrelin Levels in Saudi Obese Asthmatic School-Children—Correlation with Interleukin-4, Interleukin-5, and Interleukin-21. Int. J. Environ. Res. Public Health 2020, 17, 1656. https://doi.org/10.3390/ijerph17051656
Al-Ayed MS, Al-Shaibari KS, Alshehri D, Alzahrani MJ, Nasser I, Alaamri HS, Alaseeri WA, Mahfouz AA, Alsareii SA, Asaad AM, et al. Serum Ghrelin Levels in Saudi Obese Asthmatic School-Children—Correlation with Interleukin-4, Interleukin-5, and Interleukin-21. International Journal of Environmental Research and Public Health. 2020; 17(5):1656. https://doi.org/10.3390/ijerph17051656
Chicago/Turabian StyleAl-Ayed, Mohammed Saeed, Khaled Sadeq Al-Shaibari, Dhafer Alshehri, Mohammed Jamaan Alzahrani, Iman Nasser, Hamdan Saad Alaamri, Wed Ahmad Alaseeri, Ahmed A. Mahfouz, Saeed Ali Alsareii, Ahmed Morad Asaad, and et al. 2020. "Serum Ghrelin Levels in Saudi Obese Asthmatic School-Children—Correlation with Interleukin-4, Interleukin-5, and Interleukin-21" International Journal of Environmental Research and Public Health 17, no. 5: 1656. https://doi.org/10.3390/ijerph17051656