The Effects of Milk and Dairy Products on Sleep: A Systematic Review
Abstract
:1. Introduction
2. Materials and Methods
2.1. Protocol
2.2. Literature Search
2.3. Article Selection Process
2.4. Data Extraction
2.5. Risk of Bias: Assessment of Study Quality
2.6. Data Analyses
3. Results
3.1. Study Selection
3.2. Description of Included Studies
3.3. Main Results of the Studies
3.4. Study Quality
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
Appendix A
Study (Year) | Enrolled Subjects | Study Design | Country | Independent Variable | Dependent Variable | Results |
---|---|---|---|---|---|---|
Valtonen et al. (2005) [12] | Study 1: 59 females and 11 males (mean age = 81 ± 9 years, range = unclear); Study 2: 64 females and 17 males (mean age = 82.8 ± 8.1 years, range = unclear) | Study 1: Randomized controlled trial (RCT) (2-arms); Study 2: RCT (3-arms) | Finland | “Study 1: Group I: night milk (experimental) for 8 weeks and normal commercial milk (placebo) for 8 weeks, with a washout period of 1 week; Group II: normal daytime milk for 8 weeks, then switched to night milk after the washout period; Study 2: Group III: night milk for 8 weeks and normal daytime milk for another 8 weeks, with a washout period of 1 week; Group IV: normal milk for 8 weeks and night milk for another 8 weeks, with a washout period of 1 week. Group V: normal daytime milk throughout the experiment (control)” | Study 1: sleep quality, number of restless nights reported by nurses, Mini-Mental State Exam (MMSE) score; Study 2: sleep quality, daytime activity reported by caregivers | Study 1: decreased number of restless nights in Group I in Period 2 (normal milk), decreased sleep quality and number of restless nights in Group II in Period 2 (night milk); Study 2: increased sleep quality in Group III in Period 2 (normal milk). No effect of night milk. Increased sleep quality, morning activity and evening activity in Group IV in Period 2 (night milk). Slight increase in sleep quality In Group V in Period 2 (control). |
Steinberg et al. (1992) [13] | 57 infants | RCT (4-arms) | USA | Experimental formulae (EF): +0 (892 μmol/L tryptophan), +1 (1192 μmol/L tryptophan), +2 (1513 μmol/L tryptophan), +3 (1808 μmol/L tryptophan) | Sleep latency, quiet sleep, active rapid eye movement (REM) sleep (observation) | Shorter sleep latency in those fed with the higher tryptophan-containing formula. |
Brezinova et al. (1972) [14] | Younger group: six males and four females (mean age = 22 years, range = 20–30); older group: three males and five females (mean age = 55 years, range = 42–66) | RCT (2-arms) | Edinburgh | 32 g Horlicks solution with 250 mL of hot milk or control (inert yellow capsule) | Electroencephalography (EEG) | Younger group: diminished restlessness during sleep in Horlicks-administered group; older group: longer total sleep duration and fewer instances of awakening in the Horlicks group. |
Southwell et al. (1972) [15] | Four male students (age: unclear) | RCT (2-arms) | London | No drink (control), 350 mL of warm water, or 350 mL of warm milk plus Horlicks | Movements during sleep | Horlicks consumption reduced the number of small movements during sleep |
Jalilolghadr et al. (2011) [16] | Children (8–12 yrs; n = 8) | Experimental study | Sydney | High glycemic index (GI) drink (200 mg low fat cow’s milk with 50 g Glucodin powder) vs. low GI drink (200 mg full cream cow’s milk with 50 g honey) each for one day | PSG | The mean total arousal index in the first half of the night after the consumption of the high GI drink was greater than that of the low GI drink. (12.9 ± 4.6 vs. 9.9 ± 2.2, p = 0.03). Non-rapid eye movement (NREM) arousal index in the first half of night after the consuming the high GI drink was also higher than that of the low GI drink (12.7 ± 4.8 vs. 9.6 ± 2.3, p = 0.04). |
Tatone-Tokuda F et al. (2012) [17] | Children (6 years old: n = 1106; 7 years old: n = 1015) | Quebec Longitudinal Study of Child Development (QLSCD) (longitudinal study: 1998–2010) | Canada | Proportion who had consumed a dairy product | Categorical sleep pattern characteristics (“short-persistent⁄increasing” sleep pattern, “10-h persistent,” “11-h persistent” patterns. | Girls who had a “short-persistent⁄increasing” sleep pattern consumed milk products significantly less often (≤once per day) and soft drinks significantly more often (≥once per day) than girls with “10-h persistent” or “11-h persistent” patterns. In boys or girls; milk products or soft drinks (in boys) at the 0.05 level (data not shown). |
Aparicio S et al. (2007) [18] | Healthy infants (12–20 weeks of age; n-18) consuming artificial milk before the study | Experimental study (double-blind) | Spain (Balearic Island) | 1. Control week: each infant received commercial infant milk throughout the 24 h of the day (1.5 g tryptophan/100 g protein). 2. Other control week (inverse): control milk from 18.00 to 06.00 h, and tryptophan-enriched milk (3.4 g tryptophan/100 g protein) from 06.00 to 18.00 h. 3. The experimental week the infants received control milk during light time (from 06.00 to 18.00 h) and tryptophan enriched milk during dark time (from 18.00 to 06.00 h)” | Sleep time; sleep efficacy; sleep bouts; immobility on activity recording | Slept longer, better sleep efficiency, more immobility during the experimental week. |
Yamamura et al. (2009) [19] | 29 healthy elderly subjects (aged 60–81 years) | RCT with double-blind, cross-over design | Japan | Fermented milk vs. artificial milk (placebo) | Sleep efficacy; sleep latency; waking episodes; waking after sleep onset (WASO) based on actigraphy | There was no significant difference between the groups. Sleep efficiency had improved significantly from the baseline period in those receiving the fermented milk (p = 0.03). The number of awakening episodes decreased significantly from the baseline period in the fermented milk group (p = 0.007). |
Misra et al. (2015) [20] | 56 toddlers (Age: 14–24 months) | A double-blind RCT (between subjects) design | Malaysia | Low GI (23) milk or high GI (65) milk for a period of 3.5 days | Sleep-onset latency (SOL), total sleep time (TST), WASO, sleep efficiency (SE). | “There were no significant differences between the two GI groups for SOL, TST, WASO, and SE. There was no need for any added sugars to improve the sleep patterns of this age group. The LGI formulations are preferable, as these tend to be higher in dietary fiber and lower in refined sugars and starches.” |
Markus et al. (2005) [21] | Healthy college students with (n = 14) or without (n = 14) mild sleep complaints | A double-blind, placebo-controlled study | Netherlands | Tryptophan-rich alpha-lactalbumin (A-LAC) tryptophan-low placebo protein | The Stanford Sleepiness Scale, The Psychmotor Vigilance task, electroencephalographic recordings, concentrations of plasma tryptophan to other large neutral amino acids (Trp:LNAA) | The mean plasma Trp:LNAA was higher after the A-LAC diet condition than after the placebo diet condition (but not significantly). All subjects were less sleepy in the morning after evening intake of A-LAC than after placebo intake (but not significantly). Evening consumption of tryptophan-rich A-LAC may improve early morning performance indirectly through enhanced available brain tryptophan levels and subsequent sleep improvement. |
Sato-Mito et al. (2011) [22] | 3304 female dietetics students (Age: 18–20 years) | Cross-sectional survey | Japan | Midpoint of sleep | A validated 16-page self-administered diet history questionnaire (DHQ). | The late midpoint of sleep was significantly negatively associated with the percentage of energy derived from proteins and carbohydrates, and the energy-adjusted intake of cholesterol, potassium, calcium, magnesium, iron, zinc, vitamin A, vitamin D, thiamin, riboflavin, vitamin B6, folate, rice, vegetables, pulses, eggs, and milk and milk products. |
Grandner et al. (2014) [23] | The 2007–2008 National Health and Nutrition Examination Survey (NHANES) (n = 4552) | Cross-sectional survey | USA | The 2007–2008 National Health and Nutrition Examination Survey (NHANES)” | “Sleep symptoms (difficulty falling asleep, difficulty maintaining sleep, non-restorative sleep, and daytime sleepiness)” | Low calcium intake was associated with difficulty falling asleep and a greater duration of non-restorative sleep. |
Takada et al. (2017) [24] | 94 medical students | Double-blind, placebo-controlled trial | Japan | Lactobacillus casei strain Shirota (LcS) or non-fermented placebo milk (a daily dose of 100 mL) for 8 weeks prior to and 3 weeks after the examination (under psychological stress) | Overnight single-channel electroencephalography (EEG) recordings, subjective sleep and anxiety reporting. | There was a significant positive effect of LcS treatment on subjective assessment of sleepiness on waking and sleep duration. Sleep latency measured by EEG increased as the exam approached in the placebo group but was significantly suppressed in the LcS group. The percentage of stage 3 non-REM (N3) sleep decreased in the placebo group as the exam approached, whereas it was maintained in the LcS group throughout the trial. |
Kitano et al. (2014) [25] | 421 community-dwelling older people aged ≥65 years (mean age: 74.9 ± 5.5 years; male: 43.7%) | Cross-sectional survey | Japan | The Pittsburgh Sleep Quality Index | Dairy consumption of habitual intake of milk, yogurt, and cheese; the Physical Activity Scale for the Elderly | The combination of engaging in leisure-time physical activity (LTPA) and consuming milk or cheese is necessary as a prescription to improve latency to sleep onset for older adults suffering from DIS. |
References
- Zeng, Y.; Yang, J.; Du, J.; Pu, X.; Yang, X.; Yang, S.; Yang, T. Strategies of Functional Foods Promote Sleep in Human Being. Curr. Signal. Transduct. Ther. 2014, 9, 148–155. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Bosscher, D.; Breynaert, A.; Pieters, L.; Hermans, N. Food-based strategies to modulate the composition of the intestinal microbiota and their associated health effects. J. Physiol. Pharmacol. 2009, 60 (Suppl. 6), 5–11. [Google Scholar]
- Markus, C.R.; Olivier, B.; Panhuysen, G.E.; Van Der Gugten, J.; Alles, M.S.; Tuiten, A.; Westenberg, H.G.; Fekkes, D.; Koppeschaar, H.F.; de Haan, E.E. The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress. Am. J. Clin. Nutr. 2000, 71, 1536–1544. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Nongonierma, A.B.; FitzGerald, R.J. Bioactive properties of milk proteins in humans: A review. Peptides 2015, 73, 20–34. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Galland, L. The gut microbiome and the brain. J. Med. Food 2014, 17, 1261–1272. [Google Scholar] [CrossRef] [PubMed]
- Tillakaratne, N.J.; Medina-Kauwe, L.; Gibson, K.M. gamma-Aminobutyric acid (GABA) metabolism in mammalian neural and nonneural tissues. Comp. Biochem. Physiol. A Physiol. 1995, 112, 247–263. [Google Scholar] [CrossRef]
- Cui, R.; Li, B.; Suemaru, K.; Araki, H. Psychological stress-induced changes in sleep patterns and their generation mechanism. Yakugaku Zasshi 2008, 128, 405–411. [Google Scholar] [CrossRef]
- Cui, Y.; Miao, K.; Niyaphorn, S.; Qu, X. Production of Gamma-Aminobutyric Acid from Lactic Acid Bacteria: A Systematic Review. Int. J. Mol. Sci. 2020, 21, 995. [Google Scholar] [CrossRef] [Green Version]
- Moher, D.; Liberati, A.; Tetzlaff, J.; Altman, D.G.; Group, P. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement. Open Med. 2009, 3, e123–e130. [Google Scholar]
- Jadad, A.R.; Moore, R.A.; Carroll, D.; Jenkinson, C.; Reynolds, D.J.; Gavaghan, D.J.; McQuay, H.J. Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Control. Clin. Trials 1996, 17, 1–12. [Google Scholar] [CrossRef]
- Wells, G.A.; Shea, B.; Connell, D.O.; Peterson, J.; Welch, V.; Losos, M.; Tugwell, P. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta- Analyses. Available online: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp (accessed on 10 August 2020).
- Valtonen, M.; Niskanen, L.; Kangas, A.P.; Koskinen, T. Effect of melatonin-rich night-time milk on sleep and activity in elderly institutionalized subjects. Nord. J. Psychiatry 2005, 59, 217–221. [Google Scholar] [CrossRef] [PubMed]
- Steinberg, L.A.; O’Connell, N.C.; Hatch, T.F.; Picciano, M.F.; Birch, L.L. Tryptophan intake influences infants’ sleep latency. J. Nutr. 1992, 122, 1781–1791. [Google Scholar] [CrossRef]
- Brezinova, V.; Oswald, I. Sleep after a bedtime beverage. Br. Med. J. 1972, 2, 431–433. [Google Scholar] [CrossRef] [Green Version]
- Southwell, P.R.; Evans, C.R.; Hunt, J.N. Effect of a hot milk drink on movements during sleep. Br. Med. J. 1972, 2, 429–431. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Jalilolghadr, S.; Afaghi, A.; O’Connor, H.; Chow, C.M. Effect of low and high glycaemic index drink on sleep pattern in children. J. Pak. Med. Assoc. 2011, 61, 533–536. [Google Scholar] [PubMed]
- Tatone-Tokuda, F.; Dubois, L.; Ramsay, T.; Girard, M.; Touchette, E.; Petit, D.; Montplaisir, J.Y. Sex differences in the association between sleep duration, diet and body mass index: A birth cohort study. J. Sleep Res. 2012, 21, 448–460. [Google Scholar] [CrossRef]
- Aparicio, S.; Garau, C.; Esteban, S.; Nicolau, M.C.; Rivero, M.; Rial, R.V. Chrononutrition: Use of dissociated day/night infant milk formulas to improve the development of the wake-sleep rhythms. Effects of tryptophan. Nutr. Neurosci. 2007, 10, 137–143. [Google Scholar] [CrossRef]
- Yamamura, S.; Morishima, H.; Kumano-go, T.; Suganuma, N.; Matsumoto, H.; Adachi, H.; Sigedo, Y.; Mikami, A.; Kai, T.; Masuyama, A.; et al. The effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly subjects. Eur. J. Clin. Nutr. 2009, 63, 100–105. [Google Scholar] [CrossRef]
- Misra, S.; Khor, G.L.; Mitchell, P.; Haque, S.; Benton, D. A pilot study to determine the short-term effects of milk with differing glycaemic properties on sleep among toddlers: A randomised controlled trial. BMC Pediatr. 2015, 15, 79. [Google Scholar] [CrossRef] [Green Version]
- Markus, C.R.; Jonkman, L.M.; Lammers, J.H.; Deutz, N.E.; Messer, M.H.; Rigtering, N. Evening intake of alpha-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention. Am. J. Clin. Nutr. 2005, 81, 1026–1033. [Google Scholar] [CrossRef]
- Sato-Mito, N.; Sasaki, S.; Murakami, K.; Okubo, H.; Takahashi, Y.; Shibata, S.; Yamada, K.; Sato, K.; the Freshmen in Dietetic Courses Study II group. The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women. Sleep Med. 2011, 12, 289–294. [Google Scholar] [CrossRef] [PubMed]
- Grandner, M.A.; Jackson, N.; Gerstner, J.R.; Knutson, K.L. Sleep symptoms associated with intake of specific dietary nutrients. J. Sleep Res. 2014, 23, 22–34. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Takada, M.; Nishida, K.; Gondo, Y.; Kikuchi-Hayakawa, H.; Ishikawa, H.; Suda, K.; Kawai, M.; Hoshi, R.; Kuwano, Y.; Miyazaki, K.; et al. Beneficial effects of Lactobacillus casei strain Shirota on academic stress-induced sleep disturbance in healthy adults: A double-blind, randomised, placebo-controlled trial. Benef. Microbes. 2017, 8, 153–162. [Google Scholar] [CrossRef] [PubMed]
- Kitano, N.; Tsunoda, K.; Tsuji, T.; Osuka, Y.; Jindo, T.; Tanaka, K.; Okura, T. Association between difficulty initiating sleep in older adults and the combination of leisure-time physical activity and consumption of milk and milk products: A cross-sectional study. BMC Geriatr. 2014, 14, 118. [Google Scholar] [CrossRef] [Green Version]
- Fukushige, H.; Fukuda, Y.; Tanaka, M.; Inami, K.; Wada, K.; Tsumura, Y.; Kondo, M.; Harada, T.; Wakamura, T.; Morita, T. Effects of tryptophan-rich breakfast and light exposure during the daytime on melatonin secretion at night. J. Physiol. Anthropol. 2014, 33, 33. [Google Scholar] [CrossRef] [Green Version]
- Sanlier, N.; Sabuncular, G. Relationship between nutrition and sleep quality, focusing on the melatonin biosynthesis. Sleep Biol. Rhythms. 2020, 18, 89–99. [Google Scholar] [CrossRef]
- Misselwitz, B.; Butter, M.; Verbeke, K.; Fox, M.R. Update on lactose malabsorption and intolerance: Pathogenesis, diagnosis and clinical management. Gut 2019, 68, 2080–2091. [Google Scholar] [CrossRef] [Green Version]
- Mamalaki, E.; Anastasiou, C.A.; Ntanasi, E.; Tsapanou, A.; Kosmidis, M.H.; Dardiotis, E.; Hadjigeorgiou, G.M.; Sakka, P.; Scarmeas, N.; Yannakoulia, M. Associations between the mediterranean diet and sleep in older adults: Results from the hellenic longitudinal investigation of aging and diet study. Geriatr. Gerontol. Int. 2018, 18, 1543–1548. [Google Scholar] [CrossRef] [Green Version]
- Muscogiuri, G.; Barrea, L.; Aprano, S.; Framondi, L.; Di Matteo, R.; Laudisio, D.; Pugliese, G.; Savastano, S.; Colao, A.; on behalf of the OPERA PREVENTION Project. Sleep Quality in Obesity: Does Adherence to the Mediterranean Diet Matter? Nutrients 2020, 12, 1364. [Google Scholar] [CrossRef]
- Ozawa, M.; Ohara, T.; Ninomiya, T.; Hata, J.; Yoshida, D.; Mukai, N.; Nagata, M.; Uchida, K.; Shirota, T.; Kitazono, T.; et al. Milk and dairy consumption and risk of dementia in an elderly Japanese population: The Hisayama Study. J. Am. Geriatr. Soc. 2014, 62, 1224–1230. [Google Scholar] [CrossRef] [PubMed]
- Cuesta-Triana, F.; Verdejo-Bravo, C.; Fernandez-Perez, C.; Martin-Sanchez, F.J. Effect of Milk and Other Dairy Products on the Risk of Frailty, Sarcopenia, and Cognitive Performance Decline in the Elderly: A Systematic Review. Adv. Nutr. 2019, 10, S105–S119. [Google Scholar] [CrossRef] [PubMed]
- Almoosawi, S.; Palla, L.; Walshe, I.; Vingeliene, S.; Ellis, J.G. Long Sleep Duration and Social Jetlag Are Associated Inversely with a Healthy Dietary Pattern in Adults: Results from the UK National Diet and Nutrition Survey Rolling Programme Y1(-)4. Nutrients 2018, 10, 1131. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Raniti, M.B.; Allen, N.B.; Schwartz, O.; Waloszek, J.M.; Byrne, M.L.; Woods, M.J.; Bei, B.; Nicholas, C.L.; Trinder, J. Sleep Duration and Sleep Quality: Associations With Depressive Symptoms Across Adolescence. Behav. Sleep Med. 2017, 15, 198–215. [Google Scholar] [CrossRef] [PubMed]
Parameter | Inclusion Criteria |
---|---|
Participants | Human |
Intervention or exposure | Consumption of milk, yogurt, cheese, or other dairy products |
Comparator(s) | – |
Outcome | Sleep |
Study type | Observational study, intervention study |
#1. milk [title/abstract] | #6. sleep [title/abstract] |
#2. yogurt [title/abstract] | #7. human [text word] |
#3. “dairy product” [title/abstract] | #8. “observational study” [text word] |
#4. cheese [title/abstract] | #9. #5 and #6 and #7 and #8 |
#5. #1 or #2 or #3 or #4 |
Study (Year) | Newcastle-Ottawa Scale (NOS) Scoring | Jadad Scale Scoring | ||||||
---|---|---|---|---|---|---|---|---|
Selection | Comparability | Outcome | Total Score | Randomization | Double-Blinding | Withdrawals and Dropouts | Total Score | |
Valtonen et al. (2005) | no | yes | yes | 2 | ||||
Steinberg et al. (1992) | yes | yes | no | 2 | ||||
Brezinova et al. (1972) | no | no | no | 0 | ||||
Southwell et al. (1972) | no | no | no | 0 | ||||
Jalilolghadr et al. (2011) | yes | no | no | 1 | ||||
Aparicio S et al. (2007) | no | yes | no | 1 | ||||
Yamamura et al. (2009) | yes | yes | yes | 3 | ||||
Misra et al. (2015) | yes (extra point added) | yes (extra point added) | no | 4 | ||||
Markus et al. (2005) | no | yes (extra point added) | no | 2 | ||||
Takada et al. (2017) | yes (extra point added) | yes (extra point added) | yes | 5 | ||||
Tatone-Tokuda F et al. (2012) | ★★★ | ★ | ★★★ | 7 | ||||
Sato-Mito et al. (2011) | ★★ | ★ | 3 | |||||
Grandner et al. (2014) | ★★★ | ★ | 4 | |||||
Kitano et al. (2014) | ★★ | ★ | 3 |
Intervention | Category | Participant Age Group | Main Results | Implications |
---|---|---|---|---|
Night milk | Dairy product intake, RCT [12] | Older people | Positive and negative effects on sleep from subjective measurement | Effectiveness is inconsistent for older people with and without underlying diseases |
Fermented milk | Dairy product intake, RCT and non-RCT [19,24] | Older people | Positive effects on sleep (sleep efficacy, wake episodes on actigraphy) from objective measurement | Certain effects on sleep have been reported |
University students | Positive effects on sleep (sleep latency and stage 3 non-REM sleep measured by EEG, subjective sleep length) from objective measurement | |||
Milk plus Horlicks | Nutrients, RCT [14,15] | Adults | Positive effects on sleep (restlessness during sleep, total sleep duration and wake episode measured by EEG) from objective measurement | Certain effects on sleep have been reported |
Older people | Positive effects on sleep (small movements during sleep) from objective measurement | |||
Tryptophan | Nutritive component of dairy products, RCT and non-RCT [13,18,21] | Infants | Positive effects on sleep (observational sleep latency, quiet sleep, active REM sleep) from subjective measurement | Certain effects on sleep among infants, but no positive effects on sleep among university students have been reported |
Infants | Positive effects on sleep (sleep length, sleep efficacy on actigraphy) from objective measurement | |||
University students | No positive effects on sleep. Evening consumption improved early morning performance from subjective and objective measurement | |||
High glycemic index milk | Nutrients, RCT and non-RCT [16,20] | Toddlers | No positive effects on sleep (sleep-onset latency, total sleep time, wake after sleep onset, sleep efficiency on actigraphy) from objective measurement | High GI milk has negative effects or no positive effects on sleep compared to low GI milk |
Children | Negative effects on sleep (arousal during sleep measured by polysomnography) from objective measurement | |||
Proportion of milk consumption | Dietary habit, observational study [17,22,23,25] | Children | Significant association between milk consumption and sleep (subjective sleep length) among girls | Cross-sectional and longitudinal studies suggested the relationship between proportion of milk and dairy products consumption and sleep |
University students | Significant association between less intake of milk and milk products and late midpoint of sleep | |||
Adults | Significant association between low calcium intake and sleep (difficulty falling asleep and non-restorative sleep) | |||
Older people | Significant association between dairy products consumption plus physical activity and sleep (subjective sleep latency) |
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Komada, Y.; Okajima, I.; Kuwata, T. The Effects of Milk and Dairy Products on Sleep: A Systematic Review. Int. J. Environ. Res. Public Health 2020, 17, 9440. https://doi.org/10.3390/ijerph17249440
Komada Y, Okajima I, Kuwata T. The Effects of Milk and Dairy Products on Sleep: A Systematic Review. International Journal of Environmental Research and Public Health. 2020; 17(24):9440. https://doi.org/10.3390/ijerph17249440
Chicago/Turabian StyleKomada, Yoko, Isa Okajima, and Tamotsu Kuwata. 2020. "The Effects of Milk and Dairy Products on Sleep: A Systematic Review" International Journal of Environmental Research and Public Health 17, no. 24: 9440. https://doi.org/10.3390/ijerph17249440
APA StyleKomada, Y., Okajima, I., & Kuwata, T. (2020). The Effects of Milk and Dairy Products on Sleep: A Systematic Review. International Journal of Environmental Research and Public Health, 17(24), 9440. https://doi.org/10.3390/ijerph17249440