Next Article in Journal
Encouraging Physical Activity during and after Pregnancy in the COVID-19 Era, and beyond
Previous Article in Journal
Back Pain Related with Age, Anthropometric Variables, Sagittal Spinal Curvatures, Hamstring Extensibility, Physical Activity and Health Related Quality of Life in Male and Female High School Students
Article

Health Risk, Functional Markers and Cognitive Status in Institutionalized Older Adults: A Longitudinal Study

1
ImFINE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Sciences-INEF, Universidad Politécnica de Madrid, 28040 Madrid, Spain
2
Exercise and Health in Special Population Spanish Research Net (EXERNET), 50009 Zaragoza, Spain
3
CIBEROBN (Physiopathology of Obesity and Nutrition CB12/03/30038), 28029 Madrid, Spain
4
Department of Nutrition and Food Science, Rheinische Friedrich-Wilhelms University, 53115 Bonn, Germany
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(19), 7303; https://doi.org/10.3390/ijerph17197303
Received: 22 September 2020 / Accepted: 1 October 2020 / Published: 7 October 2020
(This article belongs to the Section Exercise and Health)
A Follow-up of vitamin B12 and lipids status is essential in older people, being closely related to non-communicable diseases. Their relationships with cognitive and physical status are not clear. The aim was to analyze the evolution of vitamin B12 and related parameters, lipid and hematological profiles, and their relationships with cognitive and physical status among institutionalized elderly. Sixty residents, ranged from 62 to 99, were evaluated. Biomarkers (vitamin B12 and related parameters, lipid and hematological profiles), functional capacity (handgrip, arm and leg strength), and cognitive status (Mini-Mental State Examination) were evaluated four times at 4-month intervals. At the beginning of the study, 63% and 70% of the sample showed abnormal homocysteine and folate values, respectively. At the end of the year, abnormal homocysteine increased to 68%, abnormal folate values decreased to 50%. Throughout the year, serum folate showed a significant increase (14.9 vs. 16.3 nmol/L), (p < 0.05). Serum cobalamin (299 vs. 273 pmol/L). HDL-cholesterol (49.9 vs. 47.0 mg/dL) and triglyceride levels (102.4 vs. 123.2 mg/dL) showed a significant decrease and increase respectively in mean values (all p < 0.05). Serum cobalamin and HDL-cholesterol were the most important biomarkers associated with cognitive function (both p < 0.05). The most relevant biomarkers associated with poor physical strength depending on the body part analyzed were low concentrations of HDL-cholesterol, LDL-cholesterol, apolipoprotein A1, and albumin (all p < 0.05). The evolution of lipid biomarkers, their significance with cognitive values, and association with handgrip, point to the importance of the handgrip measurement, a very simple test, as an important health marker. Both serum albumin and physical strength are important health markers in older people. View Full-Text
Keywords: cardiovascular biomarkers; cognitive function; functional capacity; muscle strength; older adults; geriatrics cardiovascular biomarkers; cognitive function; functional capacity; muscle strength; older adults; geriatrics
Show Figures

Figure 1

MDPI and ACS Style

Pedrero-Chamizo, R.; Albers, U.; Palacios, G.; Pietrzik, K.; Meléndez, A.; González-Gross, M. Health Risk, Functional Markers and Cognitive Status in Institutionalized Older Adults: A Longitudinal Study. Int. J. Environ. Res. Public Health 2020, 17, 7303. https://doi.org/10.3390/ijerph17197303

AMA Style

Pedrero-Chamizo R, Albers U, Palacios G, Pietrzik K, Meléndez A, González-Gross M. Health Risk, Functional Markers and Cognitive Status in Institutionalized Older Adults: A Longitudinal Study. International Journal of Environmental Research and Public Health. 2020; 17(19):7303. https://doi.org/10.3390/ijerph17197303

Chicago/Turabian Style

Pedrero-Chamizo, Raquel, Ulrike Albers, Gonzalo Palacios, Klaus Pietrzik, Agustín Meléndez, and Marcela González-Gross. 2020. "Health Risk, Functional Markers and Cognitive Status in Institutionalized Older Adults: A Longitudinal Study" International Journal of Environmental Research and Public Health 17, no. 19: 7303. https://doi.org/10.3390/ijerph17197303

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop