A Preliminary Study of the Comfort in Patients with Leukemia Staying in a Positive Pressure Isolation Room
Abstract
:1. Introduction
1.1. Background Related to Leukemia
1.2. Discomfort of Leukemia Patients Undergoing Chemotherapy
1.3. Study Aim
2. Materials and Methods
2.1. Research Design and Participants
2.2. Data Collection and Ethics Approval and Consent to Participate
2.3. Measures
2.3.1. Demographic Inventory to Measure Personal Data
2.3.2. Shortened (28-Item) General Comfort Questionnaire to Measure Comfort
2.3.3. Mishel Uncertainty in Illness Scale to Measure Uncertainty
2.3.4. Chinese Mandarin State–Trait Anxiety Inventory Y to Measure Anxiety
2.3.5. Symptom Distress Scale to Measure Physical Symptom Distress
2.3.6. Functional Assessment of Cancer Therapy–Fatigue Subscale to Measure CRF
2.4. Statistical Analysis
3. Results
3.1. Demographic and Physical Assessments
3.2. Physical Condition Measures
3.3. Trajectory of Well-being and Comfort Status
3.4. Factors Affecting Comfort in Four Time Points of Chemotherapy
4. Discussions
4.1. Innovation of the Research
4.2. Limitation and Further Research
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Physical Assessment | T0/Mean (SD) | T1/Mean (SD) | T2/Mean (SD) | T3/Mean (SD) | F | p |
---|---|---|---|---|---|---|
Body Mass Index | 23.33 (4.56) | 22.18 (4.56) | 22.21 (4.97) | 21.99 (4.95) | 0.353 | 0.787 |
Systemic Blood Pressure | 121.67 (18.28) | 115.26 (14.89) | 116.68 (15.73) | 114.68 (30.44) | 0.575 | 0.630 |
Diastolic Blood Pressure | 68.48 (8.86) | 72.63 (10.57) | 70.32 (9.10) | 76.32 ** (9.20) | 2.717 | 0.058 |
White Blood Cell | 5594.74 (8722.22) | 2482 (4255) | 626 * (1220) | 4057 (4213) | 6.135 | 0.002 |
Hemoglobin | 10.18 (1.75) | 9.31 (1.80) | 8.38 ** (1.20) | 8.58 ** (0.75) | 6.156 | 0.002 |
Albumin | 3.84 (0.87) | 3.45 (0.54) | 3.26 * (0.38) | 3.77 (0.61) | 1.88 | 0.209 |
Variables | T0/Mean (SD) | T1/Mean (SD) | T2/Mean (SD) | T3/Mean (SD) | F | p |
---|---|---|---|---|---|---|
Comfort | 109.76 (18.54) | 109.58 (15.40) | 106.74 (19.54) | 109.69 (15.29) | 0.120 | 0.948 |
Uncertainty | 71.90 (12.36) | 67.84 (13.39) | 67.05 (14.44) | 61.42 * (12.08) | 2.478 | 0.076 |
Anxiety | 50.76 (11.08) | 49.79 (8.75) | 48.84 (10.62) | 45.84 (9.19) | 0.955 | 0.425 |
FACT-F a | 97.71 (17.32) | 92.79 (17.14) | 83.05 * (26.09) | 90.58 (19.29) | 1.529 | 0.221 |
PWB | 18.00 (4.66) | 15.21 (5.71) | 12.16 ** (7.31) | 16.00 (6.12) | 3.162 | 0.034 |
SWB | 18.90 (2.89) | 18.37 (4.19) | 18.21 (5.31) | 17.79 (4.95) | 0.291 | 0.832 |
EWB | 15.95 (4.72) | 16.89 (3.54) | 17.16 (5.38) | 18.05 (4.10) | 0.772 | 0.517 |
FWB | 11.57 (6.88) | 12.47 (5.43) | 10.95 (7.26) | 12.53 (5.20) | 0.272 | 0.845 |
CRF | 33.29 (8.98) | 29.84 (9.39) | 24.58 * (12.86) | 26.21 * (10.81) | 2.767 | 0.054 |
DS | 25.90 (8.04) | 27.53 (5.90) | 30.47 (8.23) | 27.84 (7.73) | 1.072 | 0.373 |
Stage | Variables | β | T | R | R2 | Adjusted R2 | F |
---|---|---|---|---|---|---|---|
1 | Intercept | 90.113 | 3.896 ** | 0.892 | 0.796 | 0.759 | 22.046 *** |
Anxiety | −0.527 | −2.234 * | |||||
Emotional Well-being | 1.608 | 2.863 * | |||||
Physical Well-being | 1.280 | 2.452 * | |||||
2 | Intercept | 82.290 | 4.236 ** | 0.944 | 0.892 | 0.861 | 28.875 *** |
FACT-F | 0.531 | 4.635 *** | |||||
Diagnosis-to-Treatment Duration | 14.557 | 5.771 *** | |||||
Diagnosis-to-Treatment Duration | −0.754 | −3.537 ** | |||||
Age | 0.224 | 2.256 * | |||||
3 | Intercept | 162.775 | 12.948 *** | 0.882 | 0.778 | 0.750 | 27.994 *** |
Uncertainty | −0.989 | −6.020 *** | |||||
Functional Well-Being | 0.938 | 2.870 * | |||||
4 | Intercept | 117.627 | 4.572 *** | 0.856 | 0.733 | 0.679 | 13.697 *** |
FACT-F | 0.600 | 5.489 *** | |||||
Diagnosis-to-Treatment Duration | 10.830 | 2.979 *** | |||||
Hemoglobin | −7.764 | −2.820 * |
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You, W.-Y.; Yeh, T.-P.; Lee, K.-C.; Ma, W.-F. A Preliminary Study of the Comfort in Patients with Leukemia Staying in a Positive Pressure Isolation Room. Int. J. Environ. Res. Public Health 2020, 17, 3655. https://doi.org/10.3390/ijerph17103655
You W-Y, Yeh T-P, Lee K-C, Ma W-F. A Preliminary Study of the Comfort in Patients with Leukemia Staying in a Positive Pressure Isolation Room. International Journal of Environmental Research and Public Health. 2020; 17(10):3655. https://doi.org/10.3390/ijerph17103655
Chicago/Turabian StyleYou, Wun-Yu, Tzu-Pei Yeh, Kwo-Chen Lee, and Wei-Fen Ma. 2020. "A Preliminary Study of the Comfort in Patients with Leukemia Staying in a Positive Pressure Isolation Room" International Journal of Environmental Research and Public Health 17, no. 10: 3655. https://doi.org/10.3390/ijerph17103655