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Cardiovascular Disease and the Female Disadvantage

by 1,2,3
The George Institute for Global Health, University of Oxford, Oxford OX1 2BQ, UK
The George Institute for Global Health, University of New South Wales, Sydney, NSW 2050, Australia
Department of Epidemiology, Johns Hopkins University, Baltimore, MD 21287, USA
Int. J. Environ. Res. Public Health 2019, 16(7), 1165;
Received: 20 February 2019 / Revised: 17 March 2019 / Accepted: 26 March 2019 / Published: 1 April 2019
(This article belongs to the Special Issue Global Public Health and Epidemiology)
Age-standardised rates of cardiovascular disease (CVD) are substantially higher in men than women. This explains why CVD has traditionally been seen as a “man’s problem”. However, CVD is the leading cause of death in women, worldwide, and is one of the most common causes of disability-adjusted life-years lost. In general, this is under-recognised and, in several ways, women are disadvantaged in terms of CVD. Both in primary and secondary prevention, there is evidence that women are undertreated, compared to men. Women often experience heart disease in a different way compared to men, and lack of recognition of this has been shown to have adverse consequences. Female patients of male cardiac physicians have been found to have worse outcomes than their male counterparts, with no such gender differential for female cardiologists. Clinical trials in CVD primarily recruit male patients, yet, it is well recognised that some drugs act differently in women and men. Diabetes and smoking, and perhaps other risk factors, confer a greater proportional excess cardiovascular risk to women than to men, whilst adverse pregnancies and factors concerned with the female reproductive cycle give women added vulnerability to CVD. However, women’s health research is skewed towards mother and child health, an area where, arguably, the greatest public health gains have already been made, and breast cancer. Hence there is a need to redefine what is meant by “women’s health” to encompass the whole lifecycle, with a stronger emphasis on CVD and other non-communicable diseases. Sex-specific analyses of research data should be the norm, whenever feasible. View Full-Text
Keywords: women; cardiovascular disease; sex differences women; cardiovascular disease; sex differences
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MDPI and ACS Style

Woodward, M. Cardiovascular Disease and the Female Disadvantage. Int. J. Environ. Res. Public Health 2019, 16, 1165.

AMA Style

Woodward M. Cardiovascular Disease and the Female Disadvantage. International Journal of Environmental Research and Public Health. 2019; 16(7):1165.

Chicago/Turabian Style

Woodward, Mark. 2019. "Cardiovascular Disease and the Female Disadvantage" Int. J. Environ. Res. Public Health 16, no. 7: 1165.

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