Next Article in Journal
Children and Nature: Linking Accessibility of Natural Environments and Children’s Health-Related Quality of Life
Next Article in Special Issue
A Comprehensive Review of Arsenic Exposure and Risk from Rice and a Risk Assessment among a Cohort of Adolescents in Kunming, China
Previous Article in Journal
Parental Migration and Left-Behind Children’s Depressive Symptoms: Estimation Based on a Nationally-Representative Panel Dataset
Previous Article in Special Issue
PCBs and PCDD/Fs in Bluefin Tuna: Occurrence and Dietary Intake
Article Menu
Issue 6 (June) cover image

Export Article

Open AccessArticle

Association between Dietary Mineral Intake and Chronic Kidney Disease: The Health Examinees (HEXA) Study

1
Department of Medicine, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea
2
Department of Preventive Medicine, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea
3
Department of Biomedical Sciences, College of Medicine, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea
4
Cancer Research Institute, Seoul National University, 103 Daehakro, Jongnogu, Seoul 03080, Korea
5
Division of Public Health and Preventive Medicine, Seoul National University Hospital, 101 Daehakro, Jongnogu, Seoul 03080, Korea
6
Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, 101 Daehakro, Jongnogu, Seoul 03080, Korea
7
JW Lee Center for Global Medicine, College of Medicine, Seoul National University, IhwaJang-gil 71 Jongnogu, Seoul 03087, Korea
8
Department of Family Medicine, Seoul National University Hospital, 101 Daehakro, Jongnogu, Seoul 03080, Korea
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2018, 15(6), 1070; https://doi.org/10.3390/ijerph15061070
Received: 26 April 2018 / Revised: 11 May 2018 / Accepted: 11 May 2018 / Published: 24 May 2018
(This article belongs to the Special Issue Dietary Exposures)
  |  
PDF [1478 KB, uploaded 24 May 2018]
  |  

Abstract

Few studies have explored the association between mineral intake and chronic kidney disease (CKD). A cross-sectional analysis investigated the association between mineral intake (calcium, phosphorus, sodium, potassium, iron, and zinc) and CKD using the Health Examinee (HEXA) cohort of the Korean Genome and Epidemiologic Study (KoGES). For 159,711 participants, mineral intake was assessed by a food frequency questionnaire. CKD was defined as an estimated glomerular filtration rate (eGFR) of less than 60 mL/min/1.73 m2. Dietary intake of each mineral was divided into quartiles and the quartile including recommended dietary allowance (RDA) or adequate intake (AI) of each mineral was used as a reference. We assessed the association between the quartile of mineral intakes and CKD using polytomous logistic regression models. The lowest quartiles of phosphorus (≤663.68 mg/day, odds ratio [OR] = 1.64, 95% confidence interval [CI]: 1.25–2.15), potassium (≤1567.53 mg/day, OR = 1.87, 95% CI: 1.27–2.75), iron (≤6.93 mg/day, OR = 1.53, 95% CI: 1.17–2.01), and zinc (≤5.86 mg/day, OR = 1.52, 95% CI: 1.02–2.26) were associated with higher odds for advanced CKD compared with the references. The present study suggests that an inadequate intake of some minerals may be associated with CKD occurrence in the general population. Due to the reverse causation issue in this cross-sectional study design, further longitudinal prospective studies are needed in order to prove the results. View Full-Text
Keywords: chronic kidney disease; dietary mineral intake; Korean Genome and Epidemiologic Study chronic kidney disease; dietary mineral intake; Korean Genome and Epidemiologic Study
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Kim, J.; Lee, J.; Kim, K.-N.; Oh, K.-H.; Ahn, C.; Lee, J.; Kang, D.; Park, S.K. Association between Dietary Mineral Intake and Chronic Kidney Disease: The Health Examinees (HEXA) Study. Int. J. Environ. Res. Public Health 2018, 15, 1070.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top